Entity Details

Name TNKS
ID O95271
Role substrate
Enzymatic Domains
SAM 1030-1089
PROSITE-ProRule
PARP catalytic 1112-1317
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PLK1TNKSThr1128VEEEMQStIREHRDGphosphorylation
up-regulates quantity by stabilization		21818122SIGNOR-276244
PLK1TNKSSer978VVSASLIsPASTPSCphosphorylation
up-regulates quantity by stabilization		21818122SIGNOR-276242
PLK1TNKSThr930LAHGADPtMKNQEGQphosphorylation
up-regulates quantity by stabilization		21818122SIGNOR-276243
PLK1TNKSThr982SLISPAStPSCLSAAphosphorylation
up-regulates quantity by stabilization		21818122SIGNOR-276241
PLK1TNKSThr839DTQGRNStPLHLAAGphosphorylation
up-regulates quantity by stabilization		21818122SIGNOR-276245
PLK1TNKS–phosphorylation
up-regulates quantity by stabilization		21818122SIGNOR-279752
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PLK1phosphorylation
up-regulates
→
TNKS
PThr1128		phosphorylation
up-regulates
→		TNKS21818122SIGNOR-276244
PLK1phosphorylation
up-regulates
→
TNKS
PSer978		phosphorylation
up-regulates
→		TNKS21818122SIGNOR-276242
PLK1phosphorylation
up-regulates
→
TNKS
PThr930		phosphorylation
up-regulates
→		TNKS21818122SIGNOR-276243
PLK1phosphorylation
up-regulates
→
TNKS
PThr982		phosphorylation
up-regulates
→		TNKS21818122SIGNOR-276241
PLK1phosphorylation
up-regulates
→
TNKS
PThr839		phosphorylation
up-regulates
→		TNKS21818122SIGNOR-276245
Regulator Mechanism/Effect Target SIGNOR-ID
PLK1phosphorylation
→
up-regulates quantity by stabilization 		TNKSSIGNOR-276244
PLK1phosphorylation
→
up-regulates quantity by stabilization 		TNKSSIGNOR-276242
PLK1phosphorylation
→
up-regulates quantity by stabilization 		TNKSSIGNOR-276243
PLK1phosphorylation
→
up-regulates quantity by stabilization 		TNKSSIGNOR-276241
PLK1phosphorylation
→
up-regulates quantity by stabilization 		TNKSSIGNOR-276245
PLK1phosphorylation
→
up-regulates quantity by stabilization 		TNKSSIGNOR-279752