Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
PTPN11	MPZL1	Tyr263 View in OncoXplorer	NKSESVVyADIRKN	dephosphorylation down-regulates	10681522	SIGNOR-75220
SRC	MPZL1	Tyr263 View in OncoXplorer	NKSESVVyADIRKN	phosphorylation up-regulates	11751924	SIGNOR-113410
SRC	MPZL1	Tyr241 View in OncoXplorer	SHQGPVIyAQLDHSG	phosphorylation up-regulates	11751924	SIGNOR-113406

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
PTPN11	dephosphorylation down-regulates ⊣	MPZL1 PTyr263	dephosphorylation up-regulates →	MPZL1	10681522	SIGNOR-75220
SRC	phosphorylation up-regulates →	MPZL1 PTyr263	phosphorylation up-regulates →	MPZL1	11751924	SIGNOR-113410
SRC	phosphorylation up-regulates →	MPZL1 PTyr241	phosphorylation up-regulates →	MPZL1	11751924	SIGNOR-113406

Regulator	Mechanism/Effect	Target	SIGNOR-ID
PTPN11	dephosphorylation down-regulates	MPZL1	SIGNOR-75220
SRC	phosphorylation → up-regulates	MPZL1	SIGNOR-113410
SRC	phosphorylation → up-regulates	MPZL1	SIGNOR-113406