| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN11 | MPZL1 | Tyr263 | NKSESVVyADIRKN | dephosphorylation down-regulates | 10681522 | SIGNOR-75220 |
| SRC | MPZL1 | Tyr263 | NKSESVVyADIRKN | phosphorylation up-regulates | 11751924 | SIGNOR-113410 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN11 | dephosphorylation down-regulates ⊣ | MPZL1 PTyr263 | dephosphorylation up-regulates → | MPZL1 | 10681522 | SIGNOR-75220 |
| SRC | phosphorylation up-regulates → | MPZL1 PTyr263 | phosphorylation up-regulates → | MPZL1 | 11751924 | SIGNOR-113410 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PTPN11 | dephosphorylation down-regulates | MPZL1 | SIGNOR-75220 |
| SRC | phosphorylation → up-regulates | MPZL1 | SIGNOR-113410 |
