| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GRK2 | RAPGEF3 | Ser108 | S-->L | phosphorylation down-regulates activity | 28580839 | SIGNOR-280001 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GRK2 | phosphorylation up-regulates → | RAPGEF3 PSer108 | phosphorylation down-regulates ⊣ | RAPGEF3 | 28580839 | SIGNOR-280001 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| GRK2 | phosphorylation → down-regulates activity | RAPGEF3 | SIGNOR-280001 |
