Entity Details

Name TDP2
ID O95551
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK6TDP2Ser60EMERALNsYFEPPVEphosphorylation
up-regulates activity		26701725SIGNOR-278245
ACVR1BTDP2Thr88PKTYVDLtNEETTDSphosphorylation
up-regulates activity		18039968SIGNOR-262611
MAPK6TDP2Ser60EMERALNsYFEPPVEphosphorylation
up-regulates activity		26701725SIGNOR-277188
ACVR1BTDP2Thr92VDLTNEEtTDSTTSKphosphorylation
up-regulates activity		18039968SIGNOR-262612
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK6phosphorylation
up-regulates
→
TDP2
PSer60		phosphorylation
up-regulates
→		TDP226701725SIGNOR-278245
ACVR1Bphosphorylation
up-regulates
→
TDP2
PThr88		phosphorylation
up-regulates
→		TDP218039968SIGNOR-262611
MAPK6phosphorylation
up-regulates
→
TDP2
PSer60		phosphorylation
up-regulates
→		TDP226701725SIGNOR-277188
ACVR1Bphosphorylation
up-regulates
→
TDP2
PThr92		phosphorylation
up-regulates
→		TDP218039968SIGNOR-262612
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK6phosphorylation
→
up-regulates activity 		TDP2SIGNOR-278245
ACVR1Bphosphorylation
→
up-regulates activity 		TDP2SIGNOR-262611
MAPK6phosphorylation
→
up-regulates activity 		TDP2SIGNOR-277188
ACVR1Bphosphorylation
→
up-regulates activity 		TDP2SIGNOR-262612