Entity Details

Name PPP1CC_Ser8
ID O95786
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PPP1CADDX58Ser8MTTEQRRsLQAFQDYdephosphorylation
up-regulates activity		23499489SIGNOR-264581
DAPK1DDX58Ser8MTTEQRRsLQAFQDYphosphorylation
down-regulates activity		30985869SIGNOR-279519
PPP1CCDDX58Ser8MTTEQRRsLQAFQDYdephosphorylation
up-regulates activity		23499489SIGNOR-264580
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PPP1CAdephosphorylation
down-regulates
⊣
DDX58
PSer8		dephosphorylation
down-regulates
⊣		DDX5823499489SIGNOR-264581
DAPK1phosphorylation
up-regulates
→
DDX58
PSer8		phosphorylation
down-regulates
⊣		DDX5830985869SIGNOR-279519
PPP1CCdephosphorylation
down-regulates
⊣
DDX58
PSer8		dephosphorylation
down-regulates
⊣		DDX5823499489SIGNOR-264580
Regulator Mechanism/Effect Target SIGNOR-ID
PPP1CAdephosphorylation
→
up-regulates activity 		DDX58SIGNOR-264581
DAPK1phosphorylation
→
down-regulates activity 		DDX58SIGNOR-279519
PPP1CCdephosphorylation
→
up-regulates activity 		DDX58SIGNOR-264580