Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
CDK5	BAG3	Ser291 View in OncoXplorer	STPLHSPsPIRVHTV	phosphorylation down-regulates quantity by destabilization	31955914	SIGNOR-277502
PRKCD	BAG3	Ser187 View in OncoXplorer	SSSSSSAsLPSSGRS	phosphorylation up-regulates	23108398	SIGNOR-199316
ERK1/2	BAG3	Thr285 View in OncoXplorer	GSPARSStPLHSPSP	phosphorylation up-regulates activity	27659916	SIGNOR-274071
MAPK3	BAG3	Ser377 View in OncoXplorer	PVPCPPPsPGPSAVP	phosphorylation down-regulates quantity by destabilization	34215846	SIGNOR-277318
ERK1/2	BAG3	Ser289 View in OncoXplorer	RSSTPLHsPSPIRVH	phosphorylation up-regulates activity	27659916	SIGNOR-274070

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
CDK5	phosphorylation up-regulates →	BAG3 PSer291	phosphorylation down-regulates ⊣	BAG3	31955914	SIGNOR-277502
PRKCD	phosphorylation up-regulates →	BAG3 PSer187	phosphorylation up-regulates →	BAG3	23108398	SIGNOR-199316
ERK1/2	phosphorylation up-regulates →	BAG3 PThr285	phosphorylation up-regulates →	BAG3	27659916	SIGNOR-274071
MAPK3	phosphorylation up-regulates →	BAG3 PSer377	phosphorylation down-regulates ⊣	BAG3	34215846	SIGNOR-277318
ERK1/2	phosphorylation up-regulates →	BAG3 PSer289	phosphorylation up-regulates →	BAG3	27659916	SIGNOR-274070

Regulator	Mechanism/Effect	Target	SIGNOR-ID
CDK5	phosphorylation down-regulates quantity by destabilization	BAG3	SIGNOR-277502
PRKCD	phosphorylation → up-regulates	BAG3	SIGNOR-199316
ERK1/2	phosphorylation → up-regulates activity	BAG3	SIGNOR-274071
MAPK3	phosphorylation down-regulates quantity by destabilization	BAG3	SIGNOR-277318
ERK1/2	phosphorylation → up-regulates activity	BAG3	SIGNOR-274070