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Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
MAP4K4	PIK3CA	Thr1061	KMDWIFHtIKQHALN	phosphorylation down-regulates activity	38060450	SIGNOR-277921
MAP4K4	TRAF2	Ser35	LEAKYLCsACRNVLR	phosphorylation down-regulates quantity	25098764	SIGNOR-279536
MAP4K4	MAP3K1	–		phosphorylation up-regulates	8824585	SIGNOR-44040
MAP4K4	SMAD1	Thr322	SNVNRNStIENTRRH	phosphorylation down-regulates activity	21690388	SIGNOR-276335
MAP4K4	MAP3K11	Thr738	EEEPRGGtVSPPPGT	phosphorylation up-regulates activity	34511598	SIGNOR-277571