| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | SNAI1 | Ser115 | PAPSSFSsTSVSSLE | phosphorylation down-regulates | 15448698 | SIGNOR-129414 |
| STK39 | SNAI1 | Thr203 | QGHVRTHtGEKPFSC | phosphorylation up-regulates activity | 34335956 | SIGNOR-279128 |
| GSK3B | SNAI1 | Ser100 | DEDSGKGsQPPSPPS | phosphorylation down-regulates | 15448698 | SIGNOR-129398 |
| GSK3B | SNAI1 | Ser111 | SPPSPAPsSFSSTSV | phosphorylation down-regulates | 20305697 | SIGNOR-164625 |
| GSK3B | SNAI1 | Ser107 | SQPPSPPsPAPSSFS | phosphorylation down-regulates | 15448698 | SIGNOR-129406 |
| CSNK2A1 | SNAI1 | Ser11 | SFLVRKPsDPNRKPN | phosphorylation up-regulates quantity by stabilization | 19923321 | SIGNOR-161771 |
| PKN1 | SNAI1 | Ser246 | QACARTFsRMSLLHK | phosphorylation up-regulates | 15833848 | SIGNOR-135609 |
| GSK3B | SNAI1 | Ser115 | PAPSSFSsTSVSSLE | phosphorylation down-regulates | 20305697 | SIGNOR-164629 |
| GSK3B | SNAI1 | Ser104 | GKGSQPPsPPSPAPS | phosphorylation down-regulates | 20305697 | SIGNOR-164617 |
| GSK3B | SNAI1 | Ser96 | TSLSDEDsGKGSQPP | phosphorylation down-regulates | 20305697 | SIGNOR-164637 |
| CSNK2A1 | SNAI1 | Ser92 | VAELTSLsDEDSGKG | phosphorylation up-regulates | 19923321 | SIGNOR-161775 |
| GSK3B | SNAI1 | Ser96 | TSLSDEDsGKGSQPP | phosphorylation down-regulates | 15448698 | SIGNOR-129422 |
| GSK3B | SNAI1 | Ser107 | SQPPSPPsPAPSSFS | phosphorylation down-regulates | 20305697 | SIGNOR-164621 |
| PRKD1 | SNAI1 | Ser11 | SFLVRKPsDPNRKPN | phosphorylation down-regulates activity | 20940406 | SIGNOR-168537 |
| GSK3B | SNAI1 | Ser104 | GKGSQPPsPPSPAPS | phosphorylation down-regulates | 15448698 | SIGNOR-129402 |
| GSK3B | SNAI1 | Ser111 | SPPSPAPsSFSSTSV | phosphorylation down-regulates | 15448698 | SIGNOR-129410 |
| ATM | SNAI1 | Ser100 | DEDSGKGsQPPSPPS | phosphorylation up-regulates activity | 23891091 | SIGNOR-279587 |
| GSK3B | SNAI1 | Ser119 | SFSSTSVsSLEAEAY | phosphorylation down-regulates | 15448698 | SIGNOR-129418 |
| LATS2 | SNAI1 | Thr203 | QGHVRTHtGEKPFSC | phosphorylation up-regulates | 21952048 | SIGNOR-176647 |
| PRKCZ | SNAI1 | Ser249 | ARTFSRMsLLHKHQE | phosphorylation down-regulates quantity by destabilization | 30804505 | SIGNOR-277437 |
| GSK3B | SNAI1 | Ser119 | SFSSTSVsSLEAEAY | phosphorylation down-regulates | 20305697 | SIGNOR-164633 |
| DYRK2 | SNAI1 | Ser104 | GKGSQPPsPPSPAPS | phosphorylation down-regulates activity | 25603354 | SIGNOR-279328 |
| PRKAA1 | SNAI1 | Ser92 | VAELTSLsDEDSGKG | phosphorylation up-regulates | 19923321 | SIGNOR-161783 |
| GSK3B | SNAI1 | Ser100 | DEDSGKGsQPPSPPS | phosphorylation down-regulates | 20305697 | SIGNOR-164613 |
| LATS2 | SNAI1 | – | phosphorylation up-regulates quantity by stabilization | 24157836 | SIGNOR-272138 | |
| PAK1 | SNAI1 | Ser246 | QACARTFsRMSLLHK | phosphorylation up-regulates | 15833848 | SIGNOR-135605 |
| PRKAA1 | SNAI1 | Ser92 | SFLVRKPsDPNRKPN | phosphorylation up-regulates quantity by stabilization | 19923321 | SIGNOR-161779 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | phosphorylation up-regulates → | SNAI1 PSer115 | phosphorylation down-regulates ⊣ | SNAI1 | 15448698 | SIGNOR-129414 |
| STK39 | phosphorylation up-regulates → | SNAI1 PThr203 | phosphorylation up-regulates → | SNAI1 | 34335956 | SIGNOR-279128 |
| GSK3B | phosphorylation up-regulates → | SNAI1 PSer100 | phosphorylation down-regulates ⊣ | SNAI1 | 15448698 | SIGNOR-129398 |
| GSK3B | phosphorylation up-regulates → | SNAI1 PSer111 | phosphorylation down-regulates ⊣ | SNAI1 | 20305697 | SIGNOR-164625 |
| GSK3B | phosphorylation up-regulates → | SNAI1 PSer107 | phosphorylation down-regulates ⊣ | SNAI1 | 15448698 | SIGNOR-129406 |
| CSNK2A1 | phosphorylation up-regulates → | SNAI1 PSer11 | phosphorylation up-regulates → | SNAI1 | 19923321 | SIGNOR-161771 |
| PKN1 | phosphorylation up-regulates → | SNAI1 PSer246 | phosphorylation up-regulates → | SNAI1 | 15833848 | SIGNOR-135609 |
| GSK3B | phosphorylation up-regulates → | SNAI1 PSer115 | phosphorylation down-regulates ⊣ | SNAI1 | 20305697 | SIGNOR-164629 |
| GSK3B | phosphorylation up-regulates → | SNAI1 PSer104 | phosphorylation down-regulates ⊣ | SNAI1 | 20305697 | SIGNOR-164617 |
| GSK3B | phosphorylation up-regulates → | SNAI1 PSer96 | phosphorylation down-regulates ⊣ | SNAI1 | 20305697 | SIGNOR-164637 |
| CSNK2A1 | phosphorylation up-regulates → | SNAI1 PSer92 | phosphorylation up-regulates → | SNAI1 | 19923321 | SIGNOR-161775 |
| GSK3B | phosphorylation up-regulates → | SNAI1 PSer96 | phosphorylation down-regulates ⊣ | SNAI1 | 15448698 | SIGNOR-129422 |
| GSK3B | phosphorylation up-regulates → | SNAI1 PSer107 | phosphorylation down-regulates ⊣ | SNAI1 | 20305697 | SIGNOR-164621 |
| PRKD1 | phosphorylation up-regulates → | SNAI1 PSer11 | phosphorylation down-regulates ⊣ | SNAI1 | 20940406 | SIGNOR-168537 |
| GSK3B | phosphorylation up-regulates → | SNAI1 PSer104 | phosphorylation down-regulates ⊣ | SNAI1 | 15448698 | SIGNOR-129402 |
| GSK3B | phosphorylation up-regulates → | SNAI1 PSer111 | phosphorylation down-regulates ⊣ | SNAI1 | 15448698 | SIGNOR-129410 |
| ATM | phosphorylation up-regulates → | SNAI1 PSer100 | phosphorylation up-regulates → | SNAI1 | 23891091 | SIGNOR-279587 |
| GSK3B | phosphorylation up-regulates → | SNAI1 PSer119 | phosphorylation down-regulates ⊣ | SNAI1 | 15448698 | SIGNOR-129418 |
| LATS2 | phosphorylation up-regulates → | SNAI1 PThr203 | phosphorylation up-regulates → | SNAI1 | 21952048 | SIGNOR-176647 |
| PRKCZ | phosphorylation up-regulates → | SNAI1 PSer249 | phosphorylation down-regulates ⊣ | SNAI1 | 30804505 | SIGNOR-277437 |
| GSK3B | phosphorylation up-regulates → | SNAI1 PSer119 | phosphorylation down-regulates ⊣ | SNAI1 | 20305697 | SIGNOR-164633 |
| DYRK2 | phosphorylation up-regulates → | SNAI1 PSer104 | phosphorylation down-regulates ⊣ | SNAI1 | 25603354 | SIGNOR-279328 |
| PRKAA1 | phosphorylation up-regulates → | SNAI1 PSer92 | phosphorylation up-regulates → | SNAI1 | 19923321 | SIGNOR-161783 |
| GSK3B | phosphorylation up-regulates → | SNAI1 PSer100 | phosphorylation down-regulates ⊣ | SNAI1 | 20305697 | SIGNOR-164613 |
| PAK1 | phosphorylation up-regulates → | SNAI1 PSer246 | phosphorylation up-regulates → | SNAI1 | 15833848 | SIGNOR-135605 |
| PRKAA1 | phosphorylation up-regulates → | SNAI1 PSer92 | phosphorylation up-regulates → | SNAI1 | 19923321 | SIGNOR-161779 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| GSK3B | phosphorylation down-regulates | SNAI1 | SIGNOR-129414 |
| STK39 | phosphorylation → up-regulates activity | SNAI1 | SIGNOR-279128 |
| GSK3B | phosphorylation down-regulates | SNAI1 | SIGNOR-129398 |
| GSK3B | phosphorylation down-regulates | SNAI1 | SIGNOR-164625 |
| GSK3B | phosphorylation down-regulates | SNAI1 | SIGNOR-129406 |
| CSNK2A1 | phosphorylation → up-regulates quantity by stabilization | SNAI1 | SIGNOR-161771 |
| PKN1 | phosphorylation → up-regulates | SNAI1 | SIGNOR-135609 |
| GSK3B | phosphorylation down-regulates | SNAI1 | SIGNOR-164629 |
| GSK3B | phosphorylation down-regulates | SNAI1 | SIGNOR-164617 |
| GSK3B | phosphorylation down-regulates | SNAI1 | SIGNOR-164637 |
| CSNK2A1 | phosphorylation → up-regulates | SNAI1 | SIGNOR-161775 |
| GSK3B | phosphorylation down-regulates | SNAI1 | SIGNOR-129422 |
| GSK3B | phosphorylation down-regulates | SNAI1 | SIGNOR-164621 |
| PRKD1 | phosphorylation → down-regulates activity | SNAI1 | SIGNOR-168537 |
| GSK3B | phosphorylation down-regulates | SNAI1 | SIGNOR-129402 |
| GSK3B | phosphorylation down-regulates | SNAI1 | SIGNOR-129410 |
| ATM | phosphorylation → up-regulates activity | SNAI1 | SIGNOR-279587 |
| GSK3B | phosphorylation down-regulates | SNAI1 | SIGNOR-129418 |
| LATS2 | phosphorylation → up-regulates | SNAI1 | SIGNOR-176647 |
| PRKCZ | phosphorylation down-regulates quantity by destabilization | SNAI1 | SIGNOR-277437 |
| GSK3B | phosphorylation down-regulates | SNAI1 | SIGNOR-164633 |
| DYRK2 | phosphorylation → down-regulates activity | SNAI1 | SIGNOR-279328 |
| PRKAA1 | phosphorylation → up-regulates | SNAI1 | SIGNOR-161783 |
| GSK3B | phosphorylation down-regulates | SNAI1 | SIGNOR-164613 |
| LATS2 | phosphorylation → up-regulates quantity by stabilization | SNAI1 | SIGNOR-272138 |
| PAK1 | phosphorylation → up-regulates | SNAI1 | SIGNOR-135605 |
| PRKAA1 | phosphorylation → up-regulates quantity by stabilization | SNAI1 | SIGNOR-161779 |
