| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ATM | SNAI1 | Ser100 | DEDSGKGsQPPSPPS | phosphorylation up-regulates activity | 23891091 | SIGNOR-279587 |
| GSK3B | SNAI1 | Ser100 | DEDSGKGsQPPSPPS | phosphorylation down-regulates | 20305697 | SIGNOR-164613 |
| GSK3B | SNAI1 | Ser100 | DEDSGKGsQPPSPPS | phosphorylation down-regulates | 15448698 | SIGNOR-129398 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ATM | phosphorylation up-regulates → | SNAI1 PSer100 | phosphorylation up-regulates → | SNAI1 | 23891091 | SIGNOR-279587 |
| GSK3B | phosphorylation up-regulates → | SNAI1 PSer100 | phosphorylation down-regulates ⊣ | SNAI1 | 20305697 | SIGNOR-164613 |
| GSK3B | phosphorylation up-regulates → | SNAI1 PSer100 | phosphorylation down-regulates ⊣ | SNAI1 | 15448698 | SIGNOR-129398 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ATM | phosphorylation → up-regulates activity | SNAI1 | SIGNOR-279587 |
| GSK3B | phosphorylation down-regulates | SNAI1 | SIGNOR-164613 |
| GSK3B | phosphorylation down-regulates | SNAI1 | SIGNOR-129398 |
