| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | SNAI1 | Ser104 | GKGSQPPsPPSPAPS | phosphorylation down-regulates | 20305697 | SIGNOR-164617 |
| GSK3B | SNAI1 | Ser104 | GKGSQPPsPPSPAPS | phosphorylation down-regulates | 15448698 | SIGNOR-129402 |
| DYRK2 | SNAI1 | Ser104 | GKGSQPPsPPSPAPS | phosphorylation down-regulates activity | 25603354 | SIGNOR-279328 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | phosphorylation up-regulates → | SNAI1 PSer104 | phosphorylation down-regulates ⊣ | SNAI1 | 20305697 | SIGNOR-164617 |
| GSK3B | phosphorylation up-regulates → | SNAI1 PSer104 | phosphorylation down-regulates ⊣ | SNAI1 | 15448698 | SIGNOR-129402 |
| DYRK2 | phosphorylation up-regulates → | SNAI1 PSer104 | phosphorylation down-regulates ⊣ | SNAI1 | 25603354 | SIGNOR-279328 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| GSK3B | phosphorylation![]() down-regulates | SNAI1 | SIGNOR-164617 |
| GSK3B | phosphorylation![]() down-regulates | SNAI1 | SIGNOR-129402 |
| DYRK2 | phosphorylation → down-regulates activity | SNAI1 | SIGNOR-279328 |