Entity Details

Name DDAH2
ID O95865
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
TBK1DDAH2Thr211DHPYASLtLPDDAAAphosphorylation
down-regulates activity		33850055SIGNOR-275647
TBK1DDAH2Ser253QEALQKLsDVTLVPVphosphorylation
down-regulates activity		33850055SIGNOR-275646
TBK1DDAH2Ser245GGGDLPNsQEALQKLphosphorylation
down-regulates activity		33850055SIGNOR-275648
TBK1DDAH2Thr203VRAMAVLtDHPYASLphosphorylation
down-regulates activity		33850055SIGNOR-275645
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
TBK1phosphorylation
up-regulates
→
DDAH2
PThr211		phosphorylation
down-regulates
⊣		DDAH233850055SIGNOR-275647
TBK1phosphorylation
up-regulates
→
DDAH2
PSer253		phosphorylation
down-regulates
⊣		DDAH233850055SIGNOR-275646
TBK1phosphorylation
up-regulates
→
DDAH2
PSer245		phosphorylation
down-regulates
⊣		DDAH233850055SIGNOR-275648
TBK1phosphorylation
up-regulates
→
DDAH2
PThr203		phosphorylation
down-regulates
⊣		DDAH233850055SIGNOR-275645
Regulator Mechanism/Effect Target SIGNOR-ID
TBK1phosphorylation
→
down-regulates activity 		DDAH2SIGNOR-275647
TBK1phosphorylation
→
down-regulates activity 		DDAH2SIGNOR-275646
TBK1phosphorylation
→
down-regulates activity 		DDAH2SIGNOR-275648
TBK1phosphorylation
→
down-regulates activity 		DDAH2SIGNOR-275645