| Name | ABL1 |
| ID | P00519 |
| Role | kinase |
| Enzymatic Domains |
SH3 61-121 PROSITE-ProRule
SH2 127-217 PROSITE-ProRule
Protein kinase 242-493 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ABL1 | PTPN6 | Tyr564 | SKHKEDVyENLHTKN | phosphorylation up-regulates activity | 8692915 | SIGNOR-251433 |
| ABL1 | CLASRP | – | phosphorylation up-regulates activity | 24520051 | SIGNOR-280166 | |
| ABL1 | PRKD1 | Tyr502 | TTANVVYyVGENVVN | phosphorylation unknown | 12637538 | SIGNOR-246215 |
| ABL1 | RAD52 | Tyr104 | DLNNGKFyVGVCAFV | phosphorylation up-regulates activity | 12379650 | SIGNOR-247661 |
| ABL1 | JUN | Tyr170 | LHSEPPVyANLSNFN | phosphorylation unknown | 10637231 | SIGNOR-245370 |
| ABL1 | WASL | Tyr175 | EITTNRFyGPQVNNI | phosphorylation up-regulates activity | 16199863 | SIGNOR-251436 |
| ABL1 | RAPH1 | Tyr513 | GKQLYMNyQEALKRT | phosphorylation up-regulates activity | 20417104 | SIGNOR-262608 |
| ABL1 | ATR | Tyr291 | DTDQLKLyEEPLSKL | phosphorylation up-regulates | 20798688 | SIGNOR-167632 |
| ABL1 | IRF3 | Tyr292 | RLGHCHTyWAVSEEL | phosphorylation up-regulates activity | 30842273 | SIGNOR-277440 |
| ABL1 | SORBS1 | Tyr632 | Y-->N | phosphorylation up-regulates activity | 19891780 | SIGNOR-278154 |
| ABL1 | PDGFRB | Tyr970 | GEGYKKKyQQVDEEF | phosphorylation up-regulates activity | 19275932 | SIGNOR-276143 |
| ABL1 | DLG4 | Tyr533 | VTQMEVHyARPIIIL | phosphorylation up-regulates activity | 20220006 | SIGNOR-278391 |
| ABL1 | WASL | Tyr175 | EITTNRFyGPQVNNI | phosphorylation unknown | 16199863 | SIGNOR-247666 |
| ABL1 | HDAC1 | – | phosphorylation up-regulates activity | 25561363 | SIGNOR-280169 | |
| ABL1 | NOX5 | – | phosphorylation up-regulates activity | 32792487 | SIGNOR-280170 | |
| ABL1 | PITX1 | – | phosphorylation up-regulates activity | 20563669 | SIGNOR-280171 | |
| ABL1 | SORBS3 | – | phosphorylation up-regulates activity | 16831423 | SIGNOR-280172 | |
| ABL1 | RAPH1 | Tyr456 | NVYYGQDyRNKYKAP | phosphorylation up-regulates activity | 20417104 | SIGNOR-262607 |
| ABL1 | LGALS3 | Tyr118 | AGPLIVPyNLPLPGG | phosphorylation unknown | 20600357 | SIGNOR-166497 |
| ABL1 | WASF3 | Tyr337 | LPAQIIEyYNPSGPP | phosphorylation up-regulates activity | 17623672 | SIGNOR-262301 |
| ABL1 | SORBS1 | Tyr360 | Y-->K | phosphorylation up-regulates activity | 19891780 | SIGNOR-278152 |
| ABL1 | DDX5 | Tyr593 | NGMNQQAyAYPATAA | phosphorylation up-regulates | 17018282 | SIGNOR-149988 |
| ABL1 | MYOD1 | Tyr30 | FATTDDFyDDPCFDSP | phosphorylation down-regulates activity | 12415271 | SIGNOR-253055 |
| ABL1 | STAT1 | Tyr701 | DGPKGTGyIKTELIS | phosphorylation up-regulates activity | 33644712 | SIGNOR-279491 |
| ABL1 | STH | – | phosphorylation up-regulates activity | 21769920 | SIGNOR-279353 | |
| ABL1 | RAD9A | Tyr28 | SRIGDELyLEPLEDG | phosphorylation up-regulates | 11971963 | SIGNOR-86186 |
| ABL1 | PRKCD | Tyr155 | IKQAKIHyIKNHEFI | phosphorylation up-regulates activity | 28637715 | SIGNOR-279436 |
| ABL1 | PSTPIP1 | Tyr345 | PERNEGVyTAIAVQE | phosphorylation unknown | 11163214 | SIGNOR-246219 |
| ABL1 | WASF3 | Tyr151 | KKDGLKFyTDPSYFF | phosphorylation up-regulates activity | 17623672 | SIGNOR-262299 |
| ABL1 | PPARG | Tyr78 | SSISTPHyEDIPFTR | phosphorylation up-regulates quantity | 25368164 | SIGNOR-255912 |
| ABL1 | STK3/4 | – | phosphorylation up-regulates | 22590567 | SIGNOR-269946 | |
| ABL1 | STX17 | Tyr157 | SQSLTQIyALPEIPQ | phosphorylation down-regulates activity | 23006999 | SIGNOR-273538 |
| ABL1 | SRCIN1 | Tyr264 | IYRKEPLyAAFPGSH | phosphorylation unknown | 23383002 | SIGNOR-200854 |
| ABL1 | MAP3K1 | – | phosphorylation up-regulates activity | 10866655 | SIGNOR-279672 | |
| ABL1 | ABL2 | Tyr261 | GLVTTLHyPAPKCNK | phosphorylation up-regulates | 15735735 | SIGNOR-134396 |
| ABL1 | MYLK | Tyr464 | QEGSIEVyEDAGSHY | phosphorylation up-regulates | 20861316 | SIGNOR-167993 |
| ABL1 | MICAL1 | – | phosphorylation up-regulates activity | 28689759 | SIGNOR-279674 | |
| ABL1 | PTPN6 | Tyr536 | QKGQESEyGNITYPP | phosphorylation up-regulates activity | 8692915 | SIGNOR-246227 |
| ABL1 | CEBPB | Tyr78 | RAIDFSPyLEPLGAP | phosphorylation up-regulates | 19563810 | SIGNOR-186423 |
| ABL1 | GLO1 | Tyr136 | GIAVPDVySACKRFE | phosphorylation up-regulates activity | 34838714 | SIGNOR-276187 |
| ABL1 | SYK | Tyr352 | TEVYESPyADPEEIR | phosphorylation up-regulates activity | 23100514 | SIGNOR-279665 |
| ABL1 | GMFG | Tyr104 | KPEQQMMyAGSKNRL | phosphorylation down-regulates activity | 24818551 | SIGNOR-273536 |
| ABL1 | CAT | Tyr386 | YRARVANyQRDGPMC | phosphorylation up-regulates | 12950161 | SIGNOR-86585 |
| ABL1 | TP63 | Tyr290 | RQSVLVPyEPPQVGT | phosphorylation up-regulates quantity by stabilization | 19783996 | SIGNOR-260933 |
| ABL1 | JUN | Tyr170 | LHSEPPVyANLSNFN | phosphorylation up-regulates activity | 10637231 | SIGNOR-251428 |
| ABL1 | RAD51 | Tyr315 | ETRICKIyDSPCLPE | phosphorylation up-regulates activity | 10212258 | SIGNOR-251434 |
| ABL1 | RAPH1 | Tyr1226 | GGSHISGyATLRRGP | phosphorylation up-regulates activity | 20417104 | SIGNOR-262605 |
| ABL1 | DNM1L | Tyr449 | IIQHCSNySTQELLR | phosphorylation up-regulates activity | 29022905 | SIGNOR-278463 |
| ABL1 | SRCIN1 | Tyr396 | LVKGEGLyADPYGLL | phosphorylation unknown | 23383002 | SIGNOR-200858 |
| ABL1 | NCK1 | Tyr105 | VDPGERLyDLNMPAY | phosphorylation up-regulates | 22327338 | SIGNOR-196043 |
| ABL1 | ABL1 | Tyr393 | RLMTGDTyTAHAGAK | phosphorylation up-regulates activity | 8441409 | SIGNOR-39142 |
| ABL1 | RIN1 | – | phosphorylation up-regulates | 9144171 | SIGNOR-48142 | |
| ABL1 | TARDBP | Tyr43 | PGACGLRyRNPVSQC | phosphorylation up-regulates quantity | 36552734 | SIGNOR-279135 |
| ABL1 | PCNA | Tyr211 | QLTFALRyLNFFTKA | phosphorylation up-regulates activity | 23542172 | SIGNOR-279389 |
| ABL1 | WASF2 | Tyr150 | GKEALKFyTDPSYFF | phosphorylation up-regulates activity | 16899465 | SIGNOR-279390 |
| ABL1 | DCBLD2 | – | phosphorylation up-regulates activity | 29025973 | SIGNOR-280167 | |
| ABL1 | MYLK | Tyr231 | NQDDVGVyTCLVVNG | phosphorylation up-regulates | 20861316 | SIGNOR-167989 |
| ABL1 | WRN | – | phosphorylation up-regulates | 12944467 | SIGNOR-86497 | |
| ABL1 | TP63 | Tyr171 | AIPSNTDyPGPHSFD | phosphorylation up-regulates quantity by stabilization | 19783996 | SIGNOR-260932 |
| ABL1 | WASL | Tyr256 | RETSKVIyDFIEKTG | phosphorylation up-regulates activity | 16199863 | SIGNOR-251437 |
| ABL1 | MTOR | – | phosphorylation down-regulates | 10753870 | SIGNOR-76562 | |
| ABL1 | KAT5 | Tyr294 | HPPGNEIyRKGTISF | phosphorylation down-regulates activity | 24044023 | SIGNOR-276598 |
| ABL1 | BTK | Tyr223 | LKKVVALyDYMPMNA | phosphorylation down-regulates activity | 12445832 | SIGNOR-260801 |
| ABL1 | ERCC6 | Tyr932 | GANRVVIyDPDWNPS | phosphorylation up-regulates activity | 17626041 | SIGNOR-251933 |
| ABL1 | MAP4K1 | Tyr232 | FLMTKSGyQPPRLKE | phosphorylation up-regulates activity | 11278340 | SIGNOR-251429 |
| ABL1 | RAD51 | Tyr315 | ETRICKIyDSPCLPE | phosphorylation up-regulates activity | 11684015 | SIGNOR-247599 |
| ABL1 | NCOA3 | Tyr1357 | HPQAASIyQSSEMKG | phosphorylation up-regulates | 18765637 | SIGNOR-180571 |
| ABL1 | SORBS1 | Tyr326 | Y-->S | phosphorylation up-regulates activity | 19891780 | SIGNOR-278153 |
| ABL1 | CDKN1B | Tyr88 | KGSLPEFyYRPPRPP | phosphorylation down-regulates activity | 17254966 | SIGNOR-251426 |
| ABL1 | TFEB | – | phosphorylation down-regulates activity | 33163944 | SIGNOR-279583 | |
| ABL1 | EGFR | Tyr1197 | STAENAEyLRVAPQS | phosphorylation up-regulates | 16943190 | SIGNOR-149277 |
| ABL1 | RBM39 | Tyr99 | RGRYRSPySGPKFNS | phosphorylation up-regulates activity | 27018250 | SIGNOR-262610 |
| ABL1 | PDP1 | Tyr94 | SILKANEySFKVPEF | phosphorylation down-regulates activity | 24962578 | SIGNOR-276641 |
| ABL1 | LGALS3 | Tyr79 | GAPAPGVyPGPPSGP | phosphorylation unknown | 20600357 | SIGNOR-166501 |
| ABL1 | PTPN6 | Tyr536 | QKGQESEyGNITYPP | phosphorylation up-regulates activity | 12468540 | SIGNOR-246236 |
| ABL1 | PDGFRB | Tyr686 | IITEYCRyGDLVDYL | phosphorylation down-regulates | 19275932 | SIGNOR-184552 |
| ABL1 | LGALS3 | Tyr107 | AYPATGPyGAPAGPL | phosphorylation unknown | 20600357 | SIGNOR-166493 |
| ABL1 | DGCR8 | Tyr267 | KRRTEEKyGGDSDHP | phosphorylation up-regulates activity | 26126715 | SIGNOR-262604 |
| ABL1 | TOP1 | Tyr268 | AKMLDHEyTTKEIFR | phosphorylation up-regulates activity | 15448168 | SIGNOR-260775 |
| ABL1 | TERT | – | phosphorylation down-regulates activity | 10837221 | SIGNOR-279354 | |
| ABL1 | PRKD1 | Tyr432 | KEGWMVHyTSKDTLR | phosphorylation unknown | 12637538 | SIGNOR-246211 |
| ABL1 | PDGFRB | Tyr934 | AHASDEIyEIMQKCW | phosphorylation up-regulates activity | 19275932 | SIGNOR-276141 |
| ABL1 | PLCG1 | Tyr1003 | KGKKFLQyNRLQLSR | phosphorylation down-regulates activity | 12652307 | SIGNOR-276002 |
| ABL1 | STK3 | Tyr81 | MQQCDSPyVVKYYGS | phosphorylation up-regulates | 22590567 | SIGNOR-197538 |
| ABL1 | MYC | Tyr74 | Y-->P | phosphorylation up-regulates activity | 23318434 | SIGNOR-278196 |
| ABL1 | CAT | Tyr386 | YRARVANyQRDGPMC | phosphorylation up-regulates activity | 12777400 | SIGNOR-260770 |
| ABL1 | WASF3 | Tyr248 | HASDVTDySYPATPN | phosphorylation up-regulates activity | 17623672 | SIGNOR-262300 |
| ABL1 | RAD52 | Tyr104 | DLNNGKFyVGVCAFV | phosphorylation up-regulates activity | 12379650 | SIGNOR-251435 |
| ABL1 | DNM1L | Tyr266 | TDSIRDEyAFLQKKY | phosphorylation up-regulates activity | 29022905 | SIGNOR-277328 |
| ABL1 | GPX1 | Tyr98 | EILNSLKyVRPGGGF | phosphorylation up-regulates activity | 12893824 | SIGNOR-104324 |
| ABL1 | YTHDC1 | – | phosphorylation down-regulates | 15175272 | SIGNOR-125167 | |
| ABL1 | CAT | Tyr231 | NANGEAVyCKFHYKT | phosphorylation up-regulates | 12950161 | SIGNOR-86581 |
| ABL1 | ATR | Tyr310 | FPFEAEAyRNIEPVY | phosphorylation up-regulates | 20798688 | SIGNOR-167636 |
| ABL1 | MDM2 | Tyr276 | SDEDDEVyQVTVYQA | phosphorylation down-regulates | 21081495 | SIGNOR-169699 |
| ABL1 | WASF3 | Tyr486 | SRRIAVEySDSDDDS | phosphorylation up-regulates activity | 17623672 | SIGNOR-259077 |
| ABL1 | RAD51 | Tyr315 | ETRICKIyDSPCLPE | phosphorylation up-regulates activity | 10212258 | SIGNOR-260777 |
| ABL1 | EPHB2 | – | phosphorylation down-regulates | 11494128 | SIGNOR-109668 | |
| ABL1 | DNM1L | Tyr266 | TDSIRDEyAFLQKKY | phosphorylation up-regulates activity | 29022905 | SIGNOR-278462 |
| ABL1 | SPTLC1 | Tyr164 | KTEEAIIySYGFATI | phosphorylation down-regulates | 23629659 | SIGNOR-202003 |
| ABL1 | CAT | Tyr386 | YRARVANyQRDGPMC | phosphorylation up-regulates activity | 12777400 | SIGNOR-101302 |
| ABL1 | MDM2 | Tyr405 | STSSSIIySSQEDVK | phosphorylation down-regulates | 21081495 | SIGNOR-169703 |
| ABL1 | BTK | Tyr223 | LKKVVALyDYMPMNA | phosphorylation unknown | 12445832 | SIGNOR-245278 |
| ABL1 | CDKN1B | Tyr88 | KGSLPEFyYRPPRPP | phosphorylation down-regulates quantity | 17254966 | SIGNOR-245293 |
| ABL1 | DNM1L | Tyr449 | IIQHCSNySTQELLR | phosphorylation up-regulates activity | 29022905 | SIGNOR-277327 |
| ABL1 | GMNN | Tyr150 | EVAEHVQyMAELIER | phosphorylation up-regulates activity | 24789045 | SIGNOR-278505 |
| ABL1 | RAPH1 | Tyr426 | LLRASGIyYVPKGKA | phosphorylation up-regulates activity | 20417104 | SIGNOR-262606 |
| ABL1 | ESR1 | Tyr52 | DSSKPAVyNYPEGAA | phosphorylation up-regulates | 20101225 | SIGNOR-163566 |
| ABL1 | RAPGEF1 | Tyr504 | APIPSVPyAPFAAIL | phosphorylation unknown | 20581864 | SIGNOR-166422 |
| ABL1 | UBE3A | Tyr659 | GDSHPVLyQSLKDLL | phosphorylation down-regulates activity | 23581475 | SIGNOR-260930 |
| ABL1 | RAD51 | – | phosphorylation up-regulates | 10212258 | SIGNOR-67069 | |
| ABL1 | PTPN11 | Tyr580 | REDSARVyENVGLMQ | phosphorylation up-regulates activity | 18827006 | SIGNOR-278217 |
| ABL1 | TP73 | Tyr99 | SVPTHSPyAQPSSTF | phosphorylation up-regulates | 10391251 | SIGNOR-68931 |
| ABL1 | CKMT1A | Tyr153 | ASKIRSGyFDERYVL | phosphorylation up-regulates quantity by stabilization | 30174304 | SIGNOR-277406 |
| ABL1 | CAT | Tyr231 | NANGEAVyCKFHYKT | phosphorylation up-regulates activity | 12777400 | SIGNOR-101298 |
| ABL1 | YAP1 | Tyr407 | SGLSMSSySVPRTPD | phosphorylation up-regulates | 18280240 | SIGNOR-160860 |
| ABL1 | RAD9A | Tyr28 | AVHSLSRiGDELYLE | phosphorylation up-regulates activity | 11971963 | SIGNOR-260843 |
| ABL1 | ABI1 | Tyr213 | PPTVPNDyMTSPARL | phosphorylation up-regulates | 21320496 | SIGNOR-172017 |
| ABL1 | DDB2 | – | phosphorylation down-regulates | 12107171 | SIGNOR-90446 | |
| ABL1 | PLCG1 | Tyr771 | IGTAEPDyGALYEGR | phosphorylation down-regulates activity | 12652307 | SIGNOR-276001 |
| ABL1 | DNM1L | Tyr368 | CGGARICyIFHETFG | phosphorylation up-regulates activity | 29022905 | SIGNOR-277329 |
| ABL1 | MYLK | Tyr556 | LNGQPIQyARSTCEA | phosphorylation up-regulates | 20861316 | SIGNOR-167997 |
| ABL1 | NOS3 | Tyr81 | WEVGSITyDTLSAQA | phosphorylation up-regulates activity | 32653904 | SIGNOR-277519 |
| ABL1 | CRK | Tyr221 | GGPEPGPyAQPSVNT | phosphorylation down-regulates activity | 21602891 | SIGNOR-173845 |
| ABL1 | RAD51 | Tyr54 | HTVEAVAyAPKKELI | phosphorylation down-regulates | 9461559 | SIGNOR-55482 |
| ABL1 | CTTN | Tyr486 | YPAEDSTyDEYENDL | phosphorylation up-regulates activity | 20861316 | SIGNOR-278504 |
| ABL1 | PPARG | Tyr102 | YDLKLQEyQSAIKVE | phosphorylation up-regulates quantity | 25368164 | SIGNOR-262297 |
| ABL1 | PTPN6 | Tyr536 | QKGQESEyGNITYPP | phosphorylation up-regulates activity | 8692915 | SIGNOR-260820 |
| ABL1 | PTPN6 | Tyr564 | SKHKEDVyENLHTKN | phosphorylation unknown | 12468540 | SIGNOR-246240 |
| ABL1 | CAT | Tyr231 | NANGEAVyCKFHYKT | phosphorylation up-regulates activity | 12777400 | SIGNOR-260769 |
| ABL1 | PAX7 | – | phosphorylation up-regulates activity | 33777928 | SIGNOR-279773 | |
| ABL1 | PDGFRB | Tyr970 | GEGYKKKyQQVDEEF | phosphorylation down-regulates | 19275932 | SIGNOR-184556 |
| ABL1 | CDK5 | Tyr15 | EKIGEGTyGTVFKAK | phosphorylation up-regulates activity | 10896159 | SIGNOR-245288 |
| ABL1 | ZNF746 | Tyr137 | ETLVSLDyAISKPEV | phosphorylation up-regulates activity | 34581802 | SIGNOR-277626 |
| ABL1 | SNCA | Tyr39 | KTKEGVLyVGSKTKE | phosphorylation up-regulates quantity | 29103051 | SIGNOR-279582 |
| ABL1 | BCAR1 | – | phosphorylation up-regulates activity | 17615370 | SIGNOR-279671 | |
| ABL1 | STAT3 | Tyr705 | DPGSAAPyLKTKFIC | phosphorylation up-regulates activity | 23383209 | SIGNOR-279675 |
| ABL1 | MDM2 | Tyr394 | QSQESEDySQPSTSS | phosphorylation down-regulates activity | 12110584 | SIGNOR-90512 |
| ABL1 | TP63 | Tyr149 | SVTAPSPyAQPSSTF | phosphorylation up-regulates quantity by stabilization | 19783996 | SIGNOR-260934 |
| ABL1 | CASP9 | Tyr153 | LAYILSMePCGHCLI | phosphorylation up-regulates activity | 15657060 | SIGNOR-260792 |
| ABL1 | PRDX1 | Tyr194 | DVQKSKEyFSKQK | phosphorylation down-regulates activity | 20178744 | SIGNOR-276278 |
| ABL1 | RBM39 | Tyr95 | DRRFRGRyRSPYSGP | phosphorylation up-regulates activity | 27018250 | SIGNOR-262609 |
| ABL1 | ERCC6 | – | phosphorylation up-regulates activity | 17626041 | SIGNOR-279317 | |
| ABL1 | PSMA7 | Tyr153 | QTDPSGTyHAWKANA | phosphorylation down-regulates | 16678104 | SIGNOR-146585 |
| ABL1 | PRKN | Tyr143 | SPAGRSIyNSFYVYC | phosphorylation down-regulates | 20823226 | SIGNOR-167853 |
| ABL1 | PSMA7 | Tyr106 | EDPVTVEyITRYIAS | phosphorylation up-regulates quantity by stabilization | 25620702 | SIGNOR-260937 |
| ABL1 | PTPN6 | Tyr564 | SKHKEDVyENLHTKN | phosphorylation up-regulates activity | 8692915 | SIGNOR-260821 |
| ABL1 | EGFR | Tyr1172 | ISLDNPDyQQDFFPK | phosphorylation up-regulates | 16943190 | SIGNOR-149273 |
| ABL1 | CLASP2 | – | phosphorylation up-regulates quantity | 24520051 | SIGNOR-279580 | |
| ABL1 | MLH1 | – | phosphorylation up-regulates quantity by stabilization | 36338985 | SIGNOR-279581 | |
| ABL1 | PLSCR1 | Tyr69 | PVPNQPVyNQPVYNQ | phosphorylation unknown | 11390389 | SIGNOR-86013 |
| ABL1 | CD19 | Tyr508 | EDMRGILyAAPQLRS | phosphorylation up-regulates activity | 11120811 | SIGNOR-245283 |
| ABL1 | ABL1 | Tyr393 | FGLSRLMtGDTYTAH | phosphorylation up-regulates activity | 10964922 | SIGNOR-260781 |
| ABL1 | ESR1 | Tyr219 | SIQGHNDyMCPATNQ | phosphorylation up-regulates | 20101225 | SIGNOR-163562 |
| ABL1 | PDGFRB | Tyr686 | IITEYCRyGDLVDYL | phosphorylation up-regulates activity | 19275932 | SIGNOR-276142 |
| ABL1 | PDGFRB | Tyr934 | PAHASDEiYEIMQKC | phosphorylation down-regulates activity | 19275932 | SIGNOR-260931 |
| ABL1 | MUC1 | Tyr1243 | NGGSSLSyTNPAVAA | phosphorylation up-regulates quantity by stabilization | 16888623 | SIGNOR-260830 |
| ABL1 | STK4 | Tyr433 | KIPQDGDyEFLKSWT | phosphorylation up-regulates activity | 21715626 | SIGNOR-260927 |
| ABL1 | ABL1 | Tyr393 | RLMTGDTyTAHAGAK | phosphorylation up-regulates activity | 11781820 | SIGNOR-113659 |
| ABL1 | PTPN6 | Tyr564 | SKHKEDVyENLHTKN | phosphorylation unknown | 8692915 | SIGNOR-246231 |
| ABL1 | PLSCR1 | Tyr74 | PVYNQPVyNQPVGAA | phosphorylation unknown | 11390389 | SIGNOR-260808 |
| ABL1 | JAK2 | Tyr1007 | VLPQDKEyYKVKEPG | phosphorylation up-regulates activity | 11593427 | SIGNOR-245365 |
| ABL1 | RB1 | Tyr805 | RIPGGNIyISPLKSP | phosphorylation unknown | 16158058 | SIGNOR-140396 |
| ABL1 | PRKD1 | Tyr463 | NDTGSRYyKEIPLSE | phosphorylation up-regulates activity | 12637538 | SIGNOR-260791 |
| ABL1 | APBB1 | Tyr547 | VQKFQVYyLGNVPVA | phosphorylation up-regulates | 15031292 | SIGNOR-123476 |
| ABL1 | PRDX2 | Tyr193 | NVDDSKEyFSKHN | phosphorylation down-regulates activity | 20178744 | SIGNOR-276280 |
| ABL1 | ROBO1 | Tyr1073 | PSGQPTPyATTQLIQ | phosphorylation down-regulates | 10892742 | SIGNOR-78993 |
| ABL1 | PSTPIP1 | Tyr345 | PERNEGVyTAIAVQE | phosphorylation unknown | 11163214 | SIGNOR-260809 |
| ABL1 | VAV1 | – | phosphorylation up-regulates | 11790798 | SIGNOR-114091 | |
| ABL1 | PRKD1 | Tyr463 | NDTGSRYyKEIPLSE | phosphorylation up-regulates | 12637538 | SIGNOR-99255 |
| ABL1 | PLSCR1 | Tyr69 | PVPNQPVyNQPVYNQ | phosphorylation unknown | 11390389 | SIGNOR-260807 |
| ABL1 | CRK | Tyr221 | GGPEPGPyAQPSVNT | phosphorylation down-regulates activity | 21779437 | SIGNOR-175135 |
| ABL1 | RAD51 | Tyr315 | ETRICKIyDSPCLPE | phosphorylation up-regulates activity | 10212258 | SIGNOR-247594 |
| ABL1 | HDAC2 | Tyr222 | IGAGKGKyYAVNFPM | phosphorylation up-regulates quantity by stabilization | 25219501 | SIGNOR-260928 |
| ABL1 | PSTPIP1 | Tyr345 | PERNEGVyTAIAVQE | phosphorylation up-regulates activity | 11163214 | SIGNOR-251431 |
| ABL1 | AHSA1 | Tyr223 | LTSPEELyRVFTTQE | phosphorylation up-regulates activity | 26235616 | SIGNOR-260938 |
| ABL1 | CASP9 | Tyr153 | RGNADLAyILSMEPC | phosphorylation up-regulates | 15657060 | SIGNOR-133260 |
| ABL1 | FUS | Tyr526 | QDRRERPy | phosphorylation down-regulates activity | 37071594 | SIGNOR-280168 |
| ABL1 | MAVS | – | phosphorylation up-regulates activity | 19914245 | SIGNOR-279673 | |
| ABL1 | LASP1 | Tyr171 | IPTSAPVyQQPQQQP | phosphorylation up-regulates | 15138294 | SIGNOR-124719 |
| ABL1 | HIPK2 | Tyr367 | TYLQSRYyRAPEIIL | phosphorylation up-regulates activity | 25944899 | SIGNOR-260936 |
| ABL1 | PLK1 | Tyr425 | SDKYGLGyQLCDNSV | phosphorylation up-regulates activity | 27899378 | SIGNOR-260935 |
| ABL1 | RACK1 | Tyr52 | LTRDETNyGIPQRAL | phosphorylation up-regulates | 19423701 | SIGNOR-185649 |
| ABL1 | MYLK | Tyr846 | DGGGSDRyGSLRPGW | phosphorylation up-regulates | 20861316 | SIGNOR-168001 |
| ABL1 | VCL | Tyr822 | KSFLDSGyRILGAVA | phosphorylation up-regulates activity | 24751539 | SIGNOR-278464 |
| ABL1 | PLSCR1 | Tyr74 | PVYNQPVyNQPVGAA | phosphorylation unknown | 11390389 | SIGNOR-86017 |
| ABL1 | PRKD1 | Tyr463 | NDTGSRYyKEIPLSE | phosphorylation up-regulates activity | 12637538 | SIGNOR-251430 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ABL1 | phosphorylation up-regulates → | PTPN6 PTyr564 | phosphorylation up-regulates → | PTPN6 | 8692915 | SIGNOR-251433 |
| ABL1 | phosphorylation up-regulates → | PRKD1 PTyr502 | phosphorylation down-regulates ⊣ | PRKD1 | 12637538 | SIGNOR-246215 |
| ABL1 | phosphorylation up-regulates → | RAD52 PTyr104 | phosphorylation up-regulates → | RAD52 | 12379650 | SIGNOR-247661 |
| ABL1 | phosphorylation up-regulates → | JUN PTyr170 | phosphorylation down-regulates ⊣ | JUN | 10637231 | SIGNOR-245370 |
| ABL1 | phosphorylation up-regulates → | WASL PTyr175 | phosphorylation up-regulates → | WASL | 16199863 | SIGNOR-251436 |
| ABL1 | phosphorylation up-regulates → | RAPH1 PTyr513 | phosphorylation up-regulates → | RAPH1 | 20417104 | SIGNOR-262608 |
| ABL1 | phosphorylation up-regulates → | ATR PTyr291 | phosphorylation up-regulates → | ATR | 20798688 | SIGNOR-167632 |
| ABL1 | phosphorylation up-regulates → | IRF3 PTyr292 | phosphorylation up-regulates → | IRF3 | 30842273 | SIGNOR-277440 |
| ABL1 | phosphorylation up-regulates → | SORBS1 PTyr632 | phosphorylation up-regulates → | SORBS1 | 19891780 | SIGNOR-278154 |
| ABL1 | phosphorylation up-regulates → | PDGFRB PTyr970 | phosphorylation up-regulates → | PDGFRB | 19275932 | SIGNOR-276143 |
| ABL1 | phosphorylation up-regulates → | DLG4 PTyr533 | phosphorylation up-regulates → | DLG4 | 20220006 | SIGNOR-278391 |
| ABL1 | phosphorylation up-regulates → | WASL PTyr175 | phosphorylation down-regulates ⊣ | WASL | 16199863 | SIGNOR-247666 |
| ABL1 | phosphorylation up-regulates → | RAPH1 PTyr456 | phosphorylation up-regulates → | RAPH1 | 20417104 | SIGNOR-262607 |
| ABL1 | phosphorylation up-regulates → | LGALS3 PTyr118 | phosphorylation down-regulates ⊣ | LGALS3 | 20600357 | SIGNOR-166497 |
| ABL1 | phosphorylation up-regulates → | WASF3 PTyr337 | phosphorylation up-regulates → | WASF3 | 17623672 | SIGNOR-262301 |
| ABL1 | phosphorylation up-regulates → | SORBS1 PTyr360 | phosphorylation up-regulates → | SORBS1 | 19891780 | SIGNOR-278152 |
| ABL1 | phosphorylation up-regulates → | DDX5 PTyr593 | phosphorylation up-regulates → | DDX5 | 17018282 | SIGNOR-149988 |
| ABL1 | phosphorylation up-regulates → | MYOD1 PTyr30 | phosphorylation down-regulates ⊣ | MYOD1 | 12415271 | SIGNOR-253055 |
| ABL1 | phosphorylation up-regulates → | STAT1 PTyr701 | phosphorylation up-regulates → | STAT1 | 33644712 | SIGNOR-279491 |
| ABL1 | phosphorylation up-regulates → | RAD9A PTyr28 | phosphorylation up-regulates → | RAD9A | 11971963 | SIGNOR-86186 |
| ABL1 | phosphorylation up-regulates → | PRKCD PTyr155 | phosphorylation up-regulates → | PRKCD | 28637715 | SIGNOR-279436 |
| ABL1 | phosphorylation up-regulates → | PSTPIP1 PTyr345 | phosphorylation down-regulates ⊣ | PSTPIP1 | 11163214 | SIGNOR-246219 |
| ABL1 | phosphorylation up-regulates → | WASF3 PTyr151 | phosphorylation up-regulates → | WASF3 | 17623672 | SIGNOR-262299 |
| ABL1 | phosphorylation up-regulates → | PPARG PTyr78 | phosphorylation up-regulates → | PPARG | 25368164 | SIGNOR-255912 |
| ABL1 | phosphorylation up-regulates → | STX17 PTyr157 | phosphorylation down-regulates ⊣ | STX17 | 23006999 | SIGNOR-273538 |
| ABL1 | phosphorylation up-regulates → | SRCIN1 PTyr264 | phosphorylation down-regulates ⊣ | SRCIN1 | 23383002 | SIGNOR-200854 |
| ABL1 | phosphorylation up-regulates → | ABL2 PTyr261 | phosphorylation up-regulates → | ABL2 | 15735735 | SIGNOR-134396 |
| ABL1 | phosphorylation up-regulates → | MYLK PTyr464 | phosphorylation up-regulates → | MYLK | 20861316 | SIGNOR-167993 |
| ABL1 | phosphorylation up-regulates → | PTPN6 PTyr536 | phosphorylation up-regulates → | PTPN6 | 8692915 | SIGNOR-246227 |
| ABL1 | phosphorylation up-regulates → | CEBPB PTyr78 | phosphorylation up-regulates → | CEBPB | 19563810 | SIGNOR-186423 |
| ABL1 | phosphorylation up-regulates → | GLO1 PTyr136 | phosphorylation up-regulates → | GLO1 | 34838714 | SIGNOR-276187 |
| ABL1 | phosphorylation up-regulates → | SYK PTyr352 | phosphorylation up-regulates → | SYK | 23100514 | SIGNOR-279665 |
| ABL1 | phosphorylation up-regulates → | GMFG PTyr104 | phosphorylation down-regulates ⊣ | GMFG | 24818551 | SIGNOR-273536 |
| ABL1 | phosphorylation up-regulates → | CAT PTyr386 | phosphorylation up-regulates → | CAT | 12950161 | SIGNOR-86585 |
| ABL1 | phosphorylation up-regulates → | TP63 PTyr290 | phosphorylation up-regulates → | TP63 | 19783996 | SIGNOR-260933 |
| ABL1 | phosphorylation up-regulates → | JUN PTyr170 | phosphorylation up-regulates → | JUN | 10637231 | SIGNOR-251428 |
| ABL1 | phosphorylation up-regulates → | RAD51 PTyr315 | phosphorylation up-regulates → | RAD51 | 10212258 | SIGNOR-251434 |
| ABL1 | phosphorylation up-regulates → | RAPH1 PTyr1226 | phosphorylation up-regulates → | RAPH1 | 20417104 | SIGNOR-262605 |
| ABL1 | phosphorylation up-regulates → | DNM1L PTyr449 | phosphorylation up-regulates → | DNM1L | 29022905 | SIGNOR-278463 |
| ABL1 | phosphorylation up-regulates → | SRCIN1 PTyr396 | phosphorylation down-regulates ⊣ | SRCIN1 | 23383002 | SIGNOR-200858 |
| ABL1 | phosphorylation up-regulates → | NCK1 PTyr105 | phosphorylation up-regulates → | NCK1 | 22327338 | SIGNOR-196043 |
| ABL1 | phosphorylation up-regulates → | ABL1 PTyr393 | phosphorylation up-regulates → | ABL1 | 8441409 | SIGNOR-39142 |
| ABL1 | phosphorylation up-regulates → | TARDBP PTyr43 | phosphorylation up-regulates → | TARDBP | 36552734 | SIGNOR-279135 |
| ABL1 | phosphorylation up-regulates → | PCNA PTyr211 | phosphorylation up-regulates → | PCNA | 23542172 | SIGNOR-279389 |
| ABL1 | phosphorylation up-regulates → | WASF2 PTyr150 | phosphorylation up-regulates → | WASF2 | 16899465 | SIGNOR-279390 |
| ABL1 | phosphorylation up-regulates → | MYLK PTyr231 | phosphorylation up-regulates → | MYLK | 20861316 | SIGNOR-167989 |
| ABL1 | phosphorylation up-regulates → | TP63 PTyr171 | phosphorylation up-regulates → | TP63 | 19783996 | SIGNOR-260932 |
| ABL1 | phosphorylation up-regulates → | WASL PTyr256 | phosphorylation up-regulates → | WASL | 16199863 | SIGNOR-251437 |
| ABL1 | phosphorylation up-regulates → | KAT5 PTyr294 | phosphorylation down-regulates ⊣ | KAT5 | 24044023 | SIGNOR-276598 |
| ABL1 | phosphorylation up-regulates → | BTK PTyr223 | phosphorylation down-regulates ⊣ | BTK | 12445832 | SIGNOR-260801 |
| ABL1 | phosphorylation up-regulates → | ERCC6 PTyr932 | phosphorylation up-regulates → | ERCC6 | 17626041 | SIGNOR-251933 |
| ABL1 | phosphorylation up-regulates → | MAP4K1 PTyr232 | phosphorylation up-regulates → | MAP4K1 | 11278340 | SIGNOR-251429 |
| ABL1 | phosphorylation up-regulates → | RAD51 PTyr315 | phosphorylation up-regulates → | RAD51 | 11684015 | SIGNOR-247599 |
| ABL1 | phosphorylation up-regulates → | NCOA3 PTyr1357 | phosphorylation up-regulates → | NCOA3 | 18765637 | SIGNOR-180571 |
| ABL1 | phosphorylation up-regulates → | SORBS1 PTyr326 | phosphorylation up-regulates → | SORBS1 | 19891780 | SIGNOR-278153 |
| ABL1 | phosphorylation up-regulates → | CDKN1B PTyr88 | phosphorylation down-regulates ⊣ | CDKN1B | 17254966 | SIGNOR-251426 |
| ABL1 | phosphorylation up-regulates → | EGFR PTyr1197 | phosphorylation up-regulates → | EGFR | 16943190 | SIGNOR-149277 |
| ABL1 | phosphorylation up-regulates → | RBM39 PTyr99 | phosphorylation up-regulates → | RBM39 | 27018250 | SIGNOR-262610 |
| ABL1 | phosphorylation up-regulates → | PDP1 PTyr94 | phosphorylation down-regulates ⊣ | PDP1 | 24962578 | SIGNOR-276641 |
| ABL1 | phosphorylation up-regulates → | LGALS3 PTyr79 | phosphorylation down-regulates ⊣ | LGALS3 | 20600357 | SIGNOR-166501 |
| ABL1 | phosphorylation up-regulates → | PTPN6 PTyr536 | phosphorylation up-regulates → | PTPN6 | 12468540 | SIGNOR-246236 |
| ABL1 | phosphorylation up-regulates → | PDGFRB PTyr686 | phosphorylation down-regulates ⊣ | PDGFRB | 19275932 | SIGNOR-184552 |
| ABL1 | phosphorylation up-regulates → | LGALS3 PTyr107 | phosphorylation down-regulates ⊣ | LGALS3 | 20600357 | SIGNOR-166493 |
| ABL1 | phosphorylation up-regulates → | DGCR8 PTyr267 | phosphorylation up-regulates → | DGCR8 | 26126715 | SIGNOR-262604 |
| ABL1 | phosphorylation up-regulates → | TOP1 PTyr268 | phosphorylation up-regulates → | TOP1 | 15448168 | SIGNOR-260775 |
| ABL1 | phosphorylation up-regulates → | PRKD1 PTyr432 | phosphorylation down-regulates ⊣ | PRKD1 | 12637538 | SIGNOR-246211 |
| ABL1 | phosphorylation up-regulates → | PDGFRB PTyr934 | phosphorylation up-regulates → | PDGFRB | 19275932 | SIGNOR-276141 |
| ABL1 | phosphorylation up-regulates → | PLCG1 PTyr1003 | phosphorylation down-regulates ⊣ | PLCG1 | 12652307 | SIGNOR-276002 |
| ABL1 | phosphorylation up-regulates → | STK3 PTyr81 | phosphorylation up-regulates → | STK3 | 22590567 | SIGNOR-197538 |
| ABL1 | phosphorylation up-regulates → | MYC PTyr74 | phosphorylation up-regulates → | MYC | 23318434 | SIGNOR-278196 |
| ABL1 | phosphorylation up-regulates → | CAT PTyr386 | phosphorylation up-regulates → | CAT | 12777400 | SIGNOR-260770 |
| ABL1 | phosphorylation up-regulates → | WASF3 PTyr248 | phosphorylation up-regulates → | WASF3 | 17623672 | SIGNOR-262300 |
| ABL1 | phosphorylation up-regulates → | RAD52 PTyr104 | phosphorylation up-regulates → | RAD52 | 12379650 | SIGNOR-251435 |
| ABL1 | phosphorylation up-regulates → | DNM1L PTyr266 | phosphorylation up-regulates → | DNM1L | 29022905 | SIGNOR-277328 |
| ABL1 | phosphorylation up-regulates → | GPX1 PTyr98 | phosphorylation up-regulates → | GPX1 | 12893824 | SIGNOR-104324 |
| ABL1 | phosphorylation up-regulates → | CAT PTyr231 | phosphorylation up-regulates → | CAT | 12950161 | SIGNOR-86581 |
| ABL1 | phosphorylation up-regulates → | ATR PTyr310 | phosphorylation up-regulates → | ATR | 20798688 | SIGNOR-167636 |
| ABL1 | phosphorylation up-regulates → | MDM2 PTyr276 | phosphorylation down-regulates ⊣ | MDM2 | 21081495 | SIGNOR-169699 |
| ABL1 | phosphorylation up-regulates → | WASF3 PTyr486 | phosphorylation up-regulates → | WASF3 | 17623672 | SIGNOR-259077 |
| ABL1 | phosphorylation up-regulates → | RAD51 PTyr315 | phosphorylation up-regulates → | RAD51 | 10212258 | SIGNOR-260777 |
| ABL1 | phosphorylation up-regulates → | DNM1L PTyr266 | phosphorylation up-regulates → | DNM1L | 29022905 | SIGNOR-278462 |
| ABL1 | phosphorylation up-regulates → | SPTLC1 PTyr164 | phosphorylation down-regulates ⊣ | SPTLC1 | 23629659 | SIGNOR-202003 |
| ABL1 | phosphorylation up-regulates → | CAT PTyr386 | phosphorylation up-regulates → | CAT | 12777400 | SIGNOR-101302 |
| ABL1 | phosphorylation up-regulates → | MDM2 PTyr405 | phosphorylation down-regulates ⊣ | MDM2 | 21081495 | SIGNOR-169703 |
| ABL1 | phosphorylation up-regulates → | BTK PTyr223 | phosphorylation down-regulates ⊣ | BTK | 12445832 | SIGNOR-245278 |
| ABL1 | phosphorylation up-regulates → | CDKN1B PTyr88 | phosphorylation down-regulates ⊣ | CDKN1B | 17254966 | SIGNOR-245293 |
| ABL1 | phosphorylation up-regulates → | DNM1L PTyr449 | phosphorylation up-regulates → | DNM1L | 29022905 | SIGNOR-277327 |
| ABL1 | phosphorylation up-regulates → | GMNN PTyr150 | phosphorylation up-regulates → | GMNN | 24789045 | SIGNOR-278505 |
| ABL1 | phosphorylation up-regulates → | RAPH1 PTyr426 | phosphorylation up-regulates → | RAPH1 | 20417104 | SIGNOR-262606 |
| ABL1 | phosphorylation up-regulates → | ESR1 PTyr52 | phosphorylation up-regulates → | ESR1 | 20101225 | SIGNOR-163566 |
| ABL1 | phosphorylation up-regulates → | RAPGEF1 PTyr504 | phosphorylation down-regulates ⊣ | RAPGEF1 | 20581864 | SIGNOR-166422 |
| ABL1 | phosphorylation up-regulates → | UBE3A PTyr659 | phosphorylation down-regulates ⊣ | UBE3A | 23581475 | SIGNOR-260930 |
| ABL1 | phosphorylation up-regulates → | PTPN11 PTyr580 | phosphorylation up-regulates → | PTPN11 | 18827006 | SIGNOR-278217 |
| ABL1 | phosphorylation up-regulates → | TP73 PTyr99 | phosphorylation up-regulates → | TP73 | 10391251 | SIGNOR-68931 |
| ABL1 | phosphorylation up-regulates → | CKMT1A PTyr153 | phosphorylation up-regulates → | CKMT1A | 30174304 | SIGNOR-277406 |
| ABL1 | phosphorylation up-regulates → | CAT PTyr231 | phosphorylation up-regulates → | CAT | 12777400 | SIGNOR-101298 |
| ABL1 | phosphorylation up-regulates → | YAP1 PTyr407 | phosphorylation up-regulates → | YAP1 | 18280240 | SIGNOR-160860 |
| ABL1 | phosphorylation up-regulates → | RAD9A PTyr28 | phosphorylation up-regulates → | RAD9A | 11971963 | SIGNOR-260843 |
| ABL1 | phosphorylation up-regulates → | ABI1 PTyr213 | phosphorylation up-regulates → | ABI1 | 21320496 | SIGNOR-172017 |
| ABL1 | phosphorylation up-regulates → | PLCG1 PTyr771 | phosphorylation down-regulates ⊣ | PLCG1 | 12652307 | SIGNOR-276001 |
| ABL1 | phosphorylation up-regulates → | DNM1L PTyr368 | phosphorylation up-regulates → | DNM1L | 29022905 | SIGNOR-277329 |
| ABL1 | phosphorylation up-regulates → | MYLK PTyr556 | phosphorylation up-regulates → | MYLK | 20861316 | SIGNOR-167997 |
| ABL1 | phosphorylation up-regulates → | NOS3 PTyr81 | phosphorylation up-regulates → | NOS3 | 32653904 | SIGNOR-277519 |
| ABL1 | phosphorylation up-regulates → | CRK PTyr221 | phosphorylation down-regulates ⊣ | CRK | 21602891 | SIGNOR-173845 |
| ABL1 | phosphorylation up-regulates → | RAD51 PTyr54 | phosphorylation down-regulates ⊣ | RAD51 | 9461559 | SIGNOR-55482 |
| ABL1 | phosphorylation up-regulates → | CTTN PTyr486 | phosphorylation up-regulates → | CTTN | 20861316 | SIGNOR-278504 |
| ABL1 | phosphorylation up-regulates → | PPARG PTyr102 | phosphorylation up-regulates → | PPARG | 25368164 | SIGNOR-262297 |
| ABL1 | phosphorylation up-regulates → | PTPN6 PTyr536 | phosphorylation up-regulates → | PTPN6 | 8692915 | SIGNOR-260820 |
| ABL1 | phosphorylation up-regulates → | PTPN6 PTyr564 | phosphorylation down-regulates ⊣ | PTPN6 | 12468540 | SIGNOR-246240 |
| ABL1 | phosphorylation up-regulates → | CAT PTyr231 | phosphorylation up-regulates → | CAT | 12777400 | SIGNOR-260769 |
| ABL1 | phosphorylation up-regulates → | PDGFRB PTyr970 | phosphorylation down-regulates ⊣ | PDGFRB | 19275932 | SIGNOR-184556 |
| ABL1 | phosphorylation up-regulates → | CDK5 PTyr15 | phosphorylation up-regulates → | CDK5 | 10896159 | SIGNOR-245288 |
| ABL1 | phosphorylation up-regulates → | ZNF746 PTyr137 | phosphorylation up-regulates → | ZNF746 | 34581802 | SIGNOR-277626 |
| ABL1 | phosphorylation up-regulates → | SNCA PTyr39 | phosphorylation up-regulates → | SNCA | 29103051 | SIGNOR-279582 |
| ABL1 | phosphorylation up-regulates → | STAT3 PTyr705 | phosphorylation up-regulates → | STAT3 | 23383209 | SIGNOR-279675 |
| ABL1 | phosphorylation up-regulates → | MDM2 PTyr394 | phosphorylation down-regulates ⊣ | MDM2 | 12110584 | SIGNOR-90512 |
| ABL1 | phosphorylation up-regulates → | TP63 PTyr149 | phosphorylation up-regulates → | TP63 | 19783996 | SIGNOR-260934 |
| ABL1 | phosphorylation up-regulates → | CASP9 PTyr153 | phosphorylation up-regulates → | CASP9 | 15657060 | SIGNOR-260792 |
| ABL1 | phosphorylation up-regulates → | PRDX1 PTyr194 | phosphorylation down-regulates ⊣ | PRDX1 | 20178744 | SIGNOR-276278 |
| ABL1 | phosphorylation up-regulates → | RBM39 PTyr95 | phosphorylation up-regulates → | RBM39 | 27018250 | SIGNOR-262609 |
| ABL1 | phosphorylation up-regulates → | PSMA7 PTyr153 | phosphorylation down-regulates ⊣ | PSMA7 | 16678104 | SIGNOR-146585 |
| ABL1 | phosphorylation up-regulates → | PRKN PTyr143 | phosphorylation down-regulates ⊣ | PRKN | 20823226 | SIGNOR-167853 |
| ABL1 | phosphorylation up-regulates → | PSMA7 PTyr106 | phosphorylation up-regulates → | PSMA7 | 25620702 | SIGNOR-260937 |
| ABL1 | phosphorylation up-regulates → | PTPN6 PTyr564 | phosphorylation up-regulates → | PTPN6 | 8692915 | SIGNOR-260821 |
| ABL1 | phosphorylation up-regulates → | EGFR PTyr1172 | phosphorylation up-regulates → | EGFR | 16943190 | SIGNOR-149273 |
| ABL1 | phosphorylation up-regulates → | PLSCR1 PTyr69 | phosphorylation down-regulates ⊣ | PLSCR1 | 11390389 | SIGNOR-86013 |
| ABL1 | phosphorylation up-regulates → | CD19 PTyr508 | phosphorylation up-regulates → | CD19 | 11120811 | SIGNOR-245283 |
| ABL1 | phosphorylation up-regulates → | ABL1 PTyr393 | phosphorylation up-regulates → | ABL1 | 10964922 | SIGNOR-260781 |
| ABL1 | phosphorylation up-regulates → | ESR1 PTyr219 | phosphorylation up-regulates → | ESR1 | 20101225 | SIGNOR-163562 |
| ABL1 | phosphorylation up-regulates → | PDGFRB PTyr686 | phosphorylation up-regulates → | PDGFRB | 19275932 | SIGNOR-276142 |
| ABL1 | phosphorylation up-regulates → | PDGFRB PTyr934 | phosphorylation down-regulates ⊣ | PDGFRB | 19275932 | SIGNOR-260931 |
| ABL1 | phosphorylation up-regulates → | MUC1 PTyr1243 | phosphorylation up-regulates → | MUC1 | 16888623 | SIGNOR-260830 |
| ABL1 | phosphorylation up-regulates → | STK4 PTyr433 | phosphorylation up-regulates → | STK4 | 21715626 | SIGNOR-260927 |
| ABL1 | phosphorylation up-regulates → | ABL1 PTyr393 | phosphorylation up-regulates → | ABL1 | 11781820 | SIGNOR-113659 |
| ABL1 | phosphorylation up-regulates → | PTPN6 PTyr564 | phosphorylation down-regulates ⊣ | PTPN6 | 8692915 | SIGNOR-246231 |
| ABL1 | phosphorylation up-regulates → | PLSCR1 PTyr74 | phosphorylation down-regulates ⊣ | PLSCR1 | 11390389 | SIGNOR-260808 |
| ABL1 | phosphorylation up-regulates → | JAK2 PTyr1007 | phosphorylation up-regulates → | JAK2 | 11593427 | SIGNOR-245365 |
| ABL1 | phosphorylation up-regulates → | RB1 PTyr805 | phosphorylation down-regulates ⊣ | RB1 | 16158058 | SIGNOR-140396 |
| ABL1 | phosphorylation up-regulates → | PRKD1 PTyr463 | phosphorylation up-regulates → | PRKD1 | 12637538 | SIGNOR-260791 |
| ABL1 | phosphorylation up-regulates → | APBB1 PTyr547 | phosphorylation up-regulates → | APBB1 | 15031292 | SIGNOR-123476 |
| ABL1 | phosphorylation up-regulates → | PRDX2 PTyr193 | phosphorylation down-regulates ⊣ | PRDX2 | 20178744 | SIGNOR-276280 |
| ABL1 | phosphorylation up-regulates → | ROBO1 PTyr1073 | phosphorylation down-regulates ⊣ | ROBO1 | 10892742 | SIGNOR-78993 |
| ABL1 | phosphorylation up-regulates → | PSTPIP1 PTyr345 | phosphorylation down-regulates ⊣ | PSTPIP1 | 11163214 | SIGNOR-260809 |
| ABL1 | phosphorylation up-regulates → | PRKD1 PTyr463 | phosphorylation up-regulates → | PRKD1 | 12637538 | SIGNOR-99255 |
| ABL1 | phosphorylation up-regulates → | PLSCR1 PTyr69 | phosphorylation down-regulates ⊣ | PLSCR1 | 11390389 | SIGNOR-260807 |
| ABL1 | phosphorylation up-regulates → | CRK PTyr221 | phosphorylation down-regulates ⊣ | CRK | 21779437 | SIGNOR-175135 |
| ABL1 | phosphorylation up-regulates → | RAD51 PTyr315 | phosphorylation up-regulates → | RAD51 | 10212258 | SIGNOR-247594 |
| ABL1 | phosphorylation up-regulates → | HDAC2 PTyr222 | phosphorylation up-regulates → | HDAC2 | 25219501 | SIGNOR-260928 |
| ABL1 | phosphorylation up-regulates → | PSTPIP1 PTyr345 | phosphorylation up-regulates → | PSTPIP1 | 11163214 | SIGNOR-251431 |
| ABL1 | phosphorylation up-regulates → | AHSA1 PTyr223 | phosphorylation up-regulates → | AHSA1 | 26235616 | SIGNOR-260938 |
| ABL1 | phosphorylation up-regulates → | CASP9 PTyr153 | phosphorylation up-regulates → | CASP9 | 15657060 | SIGNOR-133260 |
| ABL1 | phosphorylation up-regulates → | FUS PTyr526 | phosphorylation down-regulates ⊣ | FUS | 37071594 | SIGNOR-280168 |
| ABL1 | phosphorylation up-regulates → | LASP1 PTyr171 | phosphorylation up-regulates → | LASP1 | 15138294 | SIGNOR-124719 |
| ABL1 | phosphorylation up-regulates → | HIPK2 PTyr367 | phosphorylation up-regulates → | HIPK2 | 25944899 | SIGNOR-260936 |
| ABL1 | phosphorylation up-regulates → | PLK1 PTyr425 | phosphorylation up-regulates → | PLK1 | 27899378 | SIGNOR-260935 |
| ABL1 | phosphorylation up-regulates → | RACK1 PTyr52 | phosphorylation up-regulates → | RACK1 | 19423701 | SIGNOR-185649 |
| ABL1 | phosphorylation up-regulates → | MYLK PTyr846 | phosphorylation up-regulates → | MYLK | 20861316 | SIGNOR-168001 |
| ABL1 | phosphorylation up-regulates → | VCL PTyr822 | phosphorylation up-regulates → | VCL | 24751539 | SIGNOR-278464 |
| ABL1 | phosphorylation up-regulates → | PLSCR1 PTyr74 | phosphorylation down-regulates ⊣ | PLSCR1 | 11390389 | SIGNOR-86017 |
| ABL1 | phosphorylation up-regulates → | PRKD1 PTyr463 | phosphorylation up-regulates → | PRKD1 | 12637538 | SIGNOR-251430 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ABL1 | phosphorylation → up-regulates activity | PTPN6 | SIGNOR-251433 |
| ABL1 | phosphorylation → up-regulates activity | CLASRP | SIGNOR-280166 |
| ABL1 | phosphorylation → unknown | PRKD1 | SIGNOR-246215 |
| ABL1 | phosphorylation → up-regulates activity | RAD52 | SIGNOR-247661 |
| ABL1 | phosphorylation → unknown | JUN | SIGNOR-245370 |
| ABL1 | phosphorylation → up-regulates activity | WASL | SIGNOR-251436 |
| ABL1 | phosphorylation → up-regulates activity | RAPH1 | SIGNOR-262608 |
| ABL1 | phosphorylation → up-regulates | ATR | SIGNOR-167632 |
| ABL1 | phosphorylation → up-regulates activity | IRF3 | SIGNOR-277440 |
| ABL1 | phosphorylation → up-regulates activity | SORBS1 | SIGNOR-278154 |
| ABL1 | phosphorylation → up-regulates activity | PDGFRB | SIGNOR-276143 |
| ABL1 | phosphorylation → up-regulates activity | DLG4 | SIGNOR-278391 |
| ABL1 | phosphorylation → unknown | WASL | SIGNOR-247666 |
| ABL1 | phosphorylation → up-regulates activity | HDAC1 | SIGNOR-280169 |
| ABL1 | phosphorylation → up-regulates activity | NOX5 | SIGNOR-280170 |
| ABL1 | phosphorylation → up-regulates activity | PITX1 | SIGNOR-280171 |
| ABL1 | phosphorylation → up-regulates activity | SORBS3 | SIGNOR-280172 |
| ABL1 | phosphorylation → up-regulates activity | RAPH1 | SIGNOR-262607 |
| ABL1 | phosphorylation → unknown | LGALS3 | SIGNOR-166497 |
| ABL1 | phosphorylation → up-regulates activity | WASF3 | SIGNOR-262301 |
| ABL1 | phosphorylation → up-regulates activity | SORBS1 | SIGNOR-278152 |
| ABL1 | phosphorylation → up-regulates | DDX5 | SIGNOR-149988 |
| ABL1 | phosphorylation → down-regulates activity | MYOD1 | SIGNOR-253055 |
| ABL1 | phosphorylation → up-regulates activity | STAT1 | SIGNOR-279491 |
| ABL1 | phosphorylation → up-regulates activity | STH | SIGNOR-279353 |
| ABL1 | phosphorylation → up-regulates | RAD9A | SIGNOR-86186 |
| ABL1 | phosphorylation → up-regulates activity | PRKCD | SIGNOR-279436 |
| ABL1 | phosphorylation → unknown | PSTPIP1 | SIGNOR-246219 |
| ABL1 | phosphorylation → up-regulates activity | WASF3 | SIGNOR-262299 |
| ABL1 | phosphorylation → up-regulates quantity | PPARG | SIGNOR-255912 |
| ABL1 | phosphorylation → up-regulates | STK3/4 | SIGNOR-269946 |
| ABL1 | phosphorylation → down-regulates activity | STX17 | SIGNOR-273538 |
| ABL1 | phosphorylation → unknown | SRCIN1 | SIGNOR-200854 |
| ABL1 | phosphorylation → up-regulates activity | MAP3K1 | SIGNOR-279672 |
| ABL1 | phosphorylation → up-regulates | ABL2 | SIGNOR-134396 |
| ABL1 | phosphorylation → up-regulates | MYLK | SIGNOR-167993 |
| ABL1 | phosphorylation → up-regulates activity | MICAL1 | SIGNOR-279674 |
| ABL1 | phosphorylation → up-regulates activity | PTPN6 | SIGNOR-246227 |
| ABL1 | phosphorylation → up-regulates | CEBPB | SIGNOR-186423 |
| ABL1 | phosphorylation → up-regulates activity | GLO1 | SIGNOR-276187 |
| ABL1 | phosphorylation → up-regulates activity | SYK | SIGNOR-279665 |
| ABL1 | phosphorylation → down-regulates activity | GMFG | SIGNOR-273536 |
| ABL1 | phosphorylation → up-regulates | CAT | SIGNOR-86585 |
| ABL1 | phosphorylation → up-regulates quantity by stabilization | TP63 | SIGNOR-260933 |
| ABL1 | phosphorylation → up-regulates activity | JUN | SIGNOR-251428 |
| ABL1 | phosphorylation → up-regulates activity | RAD51 | SIGNOR-251434 |
| ABL1 | phosphorylation → up-regulates activity | RAPH1 | SIGNOR-262605 |
| ABL1 | phosphorylation → up-regulates activity | DNM1L | SIGNOR-278463 |
| ABL1 | phosphorylation → unknown | SRCIN1 | SIGNOR-200858 |
| ABL1 | phosphorylation → up-regulates | NCK1 | SIGNOR-196043 |
| ABL1 | phosphorylation → up-regulates activity | ABL1 | SIGNOR-39142 |
| ABL1 | phosphorylation → up-regulates | RIN1 | SIGNOR-48142 |
| ABL1 | phosphorylation → up-regulates quantity | TARDBP | SIGNOR-279135 |
| ABL1 | phosphorylation → up-regulates activity | PCNA | SIGNOR-279389 |
| ABL1 | phosphorylation → up-regulates activity | WASF2 | SIGNOR-279390 |
| ABL1 | phosphorylation → up-regulates activity | DCBLD2 | SIGNOR-280167 |
| ABL1 | phosphorylation → up-regulates | MYLK | SIGNOR-167989 |
| ABL1 | phosphorylation → up-regulates | WRN | SIGNOR-86497 |
| ABL1 | phosphorylation → up-regulates quantity by stabilization | TP63 | SIGNOR-260932 |
| ABL1 | phosphorylation → up-regulates activity | WASL | SIGNOR-251437 |
| ABL1 | phosphorylation![]() down-regulates | MTOR | SIGNOR-76562 |
| ABL1 | phosphorylation → down-regulates activity | KAT5 | SIGNOR-276598 |
| ABL1 | phosphorylation → down-regulates activity | BTK | SIGNOR-260801 |
| ABL1 | phosphorylation → up-regulates activity | ERCC6 | SIGNOR-251933 |
| ABL1 | phosphorylation → up-regulates activity | MAP4K1 | SIGNOR-251429 |
| ABL1 | phosphorylation → up-regulates activity | RAD51 | SIGNOR-247599 |
| ABL1 | phosphorylation → up-regulates | NCOA3 | SIGNOR-180571 |
| ABL1 | phosphorylation → up-regulates activity | SORBS1 | SIGNOR-278153 |
| ABL1 | phosphorylation → down-regulates activity | CDKN1B | SIGNOR-251426 |
| ABL1 | phosphorylation → down-regulates activity | TFEB | SIGNOR-279583 |
| ABL1 | phosphorylation → up-regulates | EGFR | SIGNOR-149277 |
| ABL1 | phosphorylation → up-regulates activity | RBM39 | SIGNOR-262610 |
| ABL1 | phosphorylation → down-regulates activity | PDP1 | SIGNOR-276641 |
| ABL1 | phosphorylation → unknown | LGALS3 | SIGNOR-166501 |
| ABL1 | phosphorylation → up-regulates activity | PTPN6 | SIGNOR-246236 |
| ABL1 | phosphorylation![]() down-regulates | PDGFRB | SIGNOR-184552 |
| ABL1 | phosphorylation → unknown | LGALS3 | SIGNOR-166493 |
| ABL1 | phosphorylation → up-regulates activity | DGCR8 | SIGNOR-262604 |
| ABL1 | phosphorylation → up-regulates activity | TOP1 | SIGNOR-260775 |
| ABL1 | phosphorylation → down-regulates activity | TERT | SIGNOR-279354 |
| ABL1 | phosphorylation → unknown | PRKD1 | SIGNOR-246211 |
| ABL1 | phosphorylation → up-regulates activity | PDGFRB | SIGNOR-276141 |
| ABL1 | phosphorylation → down-regulates activity | PLCG1 | SIGNOR-276002 |
| ABL1 | phosphorylation → up-regulates | STK3 | SIGNOR-197538 |
| ABL1 | phosphorylation → up-regulates activity | MYC | SIGNOR-278196 |
| ABL1 | phosphorylation → up-regulates activity | CAT | SIGNOR-260770 |
| ABL1 | phosphorylation → up-regulates activity | WASF3 | SIGNOR-262300 |
| ABL1 | phosphorylation → up-regulates activity | RAD52 | SIGNOR-251435 |
| ABL1 | phosphorylation → up-regulates activity | DNM1L | SIGNOR-277328 |
| ABL1 | phosphorylation → up-regulates activity | GPX1 | SIGNOR-104324 |
| ABL1 | phosphorylation![]() down-regulates | YTHDC1 | SIGNOR-125167 |
| ABL1 | phosphorylation → up-regulates | CAT | SIGNOR-86581 |
| ABL1 | phosphorylation → up-regulates | ATR | SIGNOR-167636 |
| ABL1 | phosphorylation![]() down-regulates | MDM2 | SIGNOR-169699 |
| ABL1 | phosphorylation → up-regulates activity | WASF3 | SIGNOR-259077 |
| ABL1 | phosphorylation → up-regulates activity | RAD51 | SIGNOR-260777 |
| ABL1 | phosphorylation![]() down-regulates | EPHB2 | SIGNOR-109668 |
| ABL1 | phosphorylation → up-regulates activity | DNM1L | SIGNOR-278462 |
| ABL1 | phosphorylation![]() down-regulates | SPTLC1 | SIGNOR-202003 |
| ABL1 | phosphorylation → up-regulates activity | CAT | SIGNOR-101302 |
| ABL1 | phosphorylation![]() down-regulates | MDM2 | SIGNOR-169703 |
| ABL1 | phosphorylation → unknown | BTK | SIGNOR-245278 |
| ABL1 | phosphorylation → down-regulates quantity | CDKN1B | SIGNOR-245293 |
| ABL1 | phosphorylation → up-regulates activity | DNM1L | SIGNOR-277327 |
| ABL1 | phosphorylation → up-regulates activity | GMNN | SIGNOR-278505 |
| ABL1 | phosphorylation → up-regulates activity | RAPH1 | SIGNOR-262606 |
| ABL1 | phosphorylation → up-regulates | ESR1 | SIGNOR-163566 |
| ABL1 | phosphorylation → unknown | RAPGEF1 | SIGNOR-166422 |
| ABL1 | phosphorylation → down-regulates activity | UBE3A | SIGNOR-260930 |
| ABL1 | phosphorylation → up-regulates | RAD51 | SIGNOR-67069 |
| ABL1 | phosphorylation → up-regulates activity | PTPN11 | SIGNOR-278217 |
| ABL1 | phosphorylation → up-regulates | TP73 | SIGNOR-68931 |
| ABL1 | phosphorylation → up-regulates quantity by stabilization | CKMT1A | SIGNOR-277406 |
| ABL1 | phosphorylation → up-regulates activity | CAT | SIGNOR-101298 |
| ABL1 | phosphorylation → up-regulates | YAP1 | SIGNOR-160860 |
| ABL1 | phosphorylation → up-regulates activity | RAD9A | SIGNOR-260843 |
| ABL1 | phosphorylation → up-regulates | ABI1 | SIGNOR-172017 |
| ABL1 | phosphorylation![]() down-regulates | DDB2 | SIGNOR-90446 |
| ABL1 | phosphorylation → down-regulates activity | PLCG1 | SIGNOR-276001 |
| ABL1 | phosphorylation → up-regulates activity | DNM1L | SIGNOR-277329 |
| ABL1 | phosphorylation → up-regulates | MYLK | SIGNOR-167997 |
| ABL1 | phosphorylation → up-regulates activity | NOS3 | SIGNOR-277519 |
| ABL1 | phosphorylation → down-regulates activity | CRK | SIGNOR-173845 |
| ABL1 | phosphorylation![]() down-regulates | RAD51 | SIGNOR-55482 |
| ABL1 | phosphorylation → up-regulates activity | CTTN | SIGNOR-278504 |
| ABL1 | phosphorylation → up-regulates quantity | PPARG | SIGNOR-262297 |
| ABL1 | phosphorylation → up-regulates activity | PTPN6 | SIGNOR-260820 |
| ABL1 | phosphorylation → unknown | PTPN6 | SIGNOR-246240 |
| ABL1 | phosphorylation → up-regulates activity | CAT | SIGNOR-260769 |
| ABL1 | phosphorylation → up-regulates activity | PAX7 | SIGNOR-279773 |
| ABL1 | phosphorylation![]() down-regulates | PDGFRB | SIGNOR-184556 |
| ABL1 | phosphorylation → up-regulates activity | CDK5 | SIGNOR-245288 |
| ABL1 | phosphorylation → up-regulates activity | ZNF746 | SIGNOR-277626 |
| ABL1 | phosphorylation → up-regulates quantity | SNCA | SIGNOR-279582 |
| ABL1 | phosphorylation → up-regulates activity | BCAR1 | SIGNOR-279671 |
| ABL1 | phosphorylation → up-regulates activity | STAT3 | SIGNOR-279675 |
| ABL1 | phosphorylation → down-regulates activity | MDM2 | SIGNOR-90512 |
| ABL1 | phosphorylation → up-regulates quantity by stabilization | TP63 | SIGNOR-260934 |
| ABL1 | phosphorylation → up-regulates activity | CASP9 | SIGNOR-260792 |
| ABL1 | phosphorylation → down-regulates activity | PRDX1 | SIGNOR-276278 |
| ABL1 | phosphorylation → up-regulates activity | RBM39 | SIGNOR-262609 |
| ABL1 | phosphorylation → up-regulates activity | ERCC6 | SIGNOR-279317 |
| ABL1 | phosphorylation![]() down-regulates | PSMA7 | SIGNOR-146585 |
| ABL1 | phosphorylation![]() down-regulates | PRKN | SIGNOR-167853 |
| ABL1 | phosphorylation → up-regulates quantity by stabilization | PSMA7 | SIGNOR-260937 |
| ABL1 | phosphorylation → up-regulates activity | PTPN6 | SIGNOR-260821 |
| ABL1 | phosphorylation → up-regulates | EGFR | SIGNOR-149273 |
| ABL1 | phosphorylation → up-regulates quantity | CLASP2 | SIGNOR-279580 |
| ABL1 | phosphorylation → up-regulates quantity by stabilization | MLH1 | SIGNOR-279581 |
| ABL1 | phosphorylation → unknown | PLSCR1 | SIGNOR-86013 |
| ABL1 | phosphorylation → up-regulates activity | CD19 | SIGNOR-245283 |
| ABL1 | phosphorylation → up-regulates activity | ABL1 | SIGNOR-260781 |
| ABL1 | phosphorylation → up-regulates | ESR1 | SIGNOR-163562 |
| ABL1 | phosphorylation → up-regulates activity | PDGFRB | SIGNOR-276142 |
| ABL1 | phosphorylation → down-regulates activity | PDGFRB | SIGNOR-260931 |
| ABL1 | phosphorylation → up-regulates quantity by stabilization | MUC1 | SIGNOR-260830 |
| ABL1 | phosphorylation → up-regulates activity | STK4 | SIGNOR-260927 |
| ABL1 | phosphorylation → up-regulates activity | ABL1 | SIGNOR-113659 |
| ABL1 | phosphorylation → unknown | PTPN6 | SIGNOR-246231 |
| ABL1 | phosphorylation → unknown | PLSCR1 | SIGNOR-260808 |
| ABL1 | phosphorylation → up-regulates activity | JAK2 | SIGNOR-245365 |
| ABL1 | phosphorylation → unknown | RB1 | SIGNOR-140396 |
| ABL1 | phosphorylation → up-regulates activity | PRKD1 | SIGNOR-260791 |
| ABL1 | phosphorylation → up-regulates | APBB1 | SIGNOR-123476 |
| ABL1 | phosphorylation → down-regulates activity | PRDX2 | SIGNOR-276280 |
| ABL1 | phosphorylation![]() down-regulates | ROBO1 | SIGNOR-78993 |
| ABL1 | phosphorylation → unknown | PSTPIP1 | SIGNOR-260809 |
| ABL1 | phosphorylation → up-regulates | VAV1 | SIGNOR-114091 |
| ABL1 | phosphorylation → up-regulates | PRKD1 | SIGNOR-99255 |
| ABL1 | phosphorylation → unknown | PLSCR1 | SIGNOR-260807 |
| ABL1 | phosphorylation → down-regulates activity | CRK | SIGNOR-175135 |
| ABL1 | phosphorylation → up-regulates activity | RAD51 | SIGNOR-247594 |
| ABL1 | phosphorylation → up-regulates quantity by stabilization | HDAC2 | SIGNOR-260928 |
| ABL1 | phosphorylation → up-regulates activity | PSTPIP1 | SIGNOR-251431 |
| ABL1 | phosphorylation → up-regulates activity | AHSA1 | SIGNOR-260938 |
| ABL1 | phosphorylation → up-regulates | CASP9 | SIGNOR-133260 |
| ABL1 | phosphorylation → down-regulates activity | FUS | SIGNOR-280168 |
| ABL1 | phosphorylation → up-regulates activity | MAVS | SIGNOR-279673 |
| ABL1 | phosphorylation → up-regulates | LASP1 | SIGNOR-124719 |
| ABL1 | phosphorylation → up-regulates activity | HIPK2 | SIGNOR-260936 |
| ABL1 | phosphorylation → up-regulates activity | PLK1 | SIGNOR-260935 |
| ABL1 | phosphorylation → up-regulates | RACK1 | SIGNOR-185649 |
| ABL1 | phosphorylation → up-regulates | MYLK | SIGNOR-168001 |
| ABL1 | phosphorylation → up-regulates activity | VCL | SIGNOR-278464 |
| ABL1 | phosphorylation → unknown | PLSCR1 | SIGNOR-86017 |
| ABL1 | phosphorylation → up-regulates activity | PRKD1 | SIGNOR-251430 |