Entity Details

Name PDGFRB_Tyr226
ID P00519
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PDGFRBABL1Tyr226KRNKPTVyGVSPNYDphosphorylation
up-regulates activity		19275932SIGNOR-278319
SRCABL1Tyr226KRNKPTVyGVSPNYDphosphorylation
up-regulates activity		11847100SIGNOR-246307
PTPN13ABL1Tyr226KRNKPTVyGVSPNYDdephosphorylation
down-regulates activity		28924170SIGNOR-277012
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PDGFRBphosphorylation
up-regulates
→
ABL1
PTyr226		phosphorylation
up-regulates
→		ABL119275932SIGNOR-278319
SRCphosphorylation
up-regulates
→
ABL1
PTyr226		phosphorylation
up-regulates
→		ABL111847100SIGNOR-246307
PTPN13dephosphorylation
down-regulates
⊣
ABL1
PTyr226		dephosphorylation
up-regulates
→		ABL128924170SIGNOR-277012
Regulator Mechanism/Effect Target SIGNOR-ID
PDGFRBphosphorylation
→
up-regulates activity 		ABL1SIGNOR-278319
SRCphosphorylation
→
up-regulates activity 		ABL1SIGNOR-246307
PTPN13dephosphorylation
→
down-regulates activity 		ABL1SIGNOR-277012