| Name | EGFR |
| ID | P00533 |
| Role | kinase |
| Enzymatic Domains |
Protein kinase 712-979 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EGFR | EGFR | Tyr1172 | ISLDNPDyQQDFFPK | phosphorylation up-regulates activity | 16122376 | SIGNOR-236531 |
| EGFR | PPARG | Tyr102 | YDLKLQEyQSAIKVE | phosphorylation down-regulates quantity by destabilization | 26718225 | SIGNOR-277190 |
| EGFR | TRIP13 | Tyr56 | HNIVFGDyTWTEFDE | phosphorylation up-regulates quantity | 32860853 | SIGNOR-265083 |
| EGFR | CALM1 | Tyr100 | FDKDGNGyISAAELR | phosphorylation down-regulates | 3415247 | SIGNOR-24778 |
| EGFR | PELI1 | Thr264 | EGLSHTPtVKHLEAL | phosphorylation up-regulates activity | 36841821 | SIGNOR-277874 |
| EGFR | ACAT1 | – | phosphorylation up-regulates activity | 27867011 | SIGNOR-279996 | |
| EGFR | CBL | Tyr371 | TQEQYELyCEMGSTF | phosphorylation up-regulates activity | 29920512 | SIGNOR-279998 |
| EGFR | MST1R | – | phosphorylation up-regulates activity | 23799848 | SIGNOR-280000 | |
| EGFR | NOTCH3 | – | phosphorylation up-regulates activity | 25125655 | SIGNOR-280002 | |
| EGFR | ERBB2 | Tyr1248 | PTAENPEyLGLDVPV | phosphorylation up-regulates activity | 12354693 | SIGNOR-251094 |
| EGFR | RASA1 | Tyr460 | TVDGKEIyNTIRRKT | phosphorylation unknown | 1850098 | SIGNOR-21875 |
| EGFR | ESR1 | – | phosphorylation up-regulates | 11887937 | SIGNOR-115734 | |
| EGFR | USP8 | Tyr810 | DYFNRNCyQDDINRS | phosphorylation up-regulates activity | 29472535 | SIGNOR-279038 |
| EGFR | GRK2 | Tyr13 | AVLADVSyLMAMEKS | phosphorylation up-regulates activity | 23904266 | SIGNOR-279368 |
| EGFR | ERBB3 | Tyr1289 | CPASEQGyEEMRAFQ | phosphorylation up-regulates | 7929151 | SIGNOR-34752 |
| EGFR | GPRC5A | Tyr350 | WPSPYKDyEVKKEGS | phosphorylation down-regulates activity | 25311788 | SIGNOR-278336 |
| EGFR | STAT5B | Tyr740 | AVCPQAHyNMYPQNP | phosphorylation up-regulates | 11751923 | SIGNOR-113397 |
| EGFR | PLCG1 | Tyr783 | EGRNPGFyVEANPMP | phosphorylation up-regulates | 9176240 | SIGNOR-48872 |
| EGFR | STAM2 | Tyr192 | HTETKSLyPSSEIQL | phosphorylation unknown | 11687594 | SIGNOR-251097 |
| EGFR | PTK2 | Tyr5 | yLDPNLNH | phosphorylation up-regulates | 20802513 | SIGNOR-167650 |
| EGFR | STAT5B | Tyr699 | TAKAVDGyVKPQIKQ | phosphorylation up-regulates activity | 11751923 | SIGNOR-251098 |
| EGFR | ZNRF1 | Tyr103 | TYAHGNGyQETGGGH | phosphorylation up-regulates activity | 26572619 | SIGNOR-279522 |
| EGFR | CTNNB1 | Tyr654 | RNEGVATyAAAVLFR | phosphorylation up-regulates activity | 25164010 | SIGNOR-278308 |
| EGFR | PLCG1 | Tyr771 | IGTAEPDyGALYEGR | phosphorylation up-regulates | 1689310 | SIGNOR-20984 |
| EGFR | USP8 | Tyr717 | PSKLKRSySSPDITQ | phosphorylation up-regulates activity | 29472535 | SIGNOR-279037 |
| EGFR | GAB1 | Tyr285 | TEADGELyVFNTPSG | phosphorylation up-regulates | 9890893 | SIGNOR-236400 |
| EGFR | CTNNB1 | Tyr142 | AVVNLINyQDDAELA | phosphorylation up-regulates activity | 22558232 | SIGNOR-278309 |
| EGFR | DOCK1 | Ser1250 | HAKLLKWsEDVCVAH | phosphorylation up-regulates activity | 23728337 | SIGNOR-279329 |
| EGFR | PTPN11 | Tyr542 | SKRKGHEyTNIKYSL | phosphorylation up-regulates activity | 19427850 | SIGNOR-279460 |
| EGFR | CALM2 | Tyr100 | FDKDGNGyISAAELR | phosphorylation down-regulates | 3415247 | SIGNOR-266319 |
| EGFR | GAB1 | Tyr373 | ASDTDSSyCIPTAGM | phosphorylation up-regulates activity | 9890893 | SIGNOR-236408 |
| EGFR | PIK3C2B | – | phosphorylation up-regulates | 10805725 | SIGNOR-77195 | |
| EGFR | GAB1 | Tyr627 | KGDKQVEyLDLDLDS | phosphorylation up-regulates | 9890893 | SIGNOR-236392 |
| EGFR | EGFR | Tyr869 | LGAEEKEyHAEGGKV | phosphorylation up-regulates activity | 10653583 | SIGNOR-236487 |
| EGFR | EGFR | Tyr1197 | STAENAEyLRVAPQS | phosphorylation up-regulates activity | 16122376 | SIGNOR-235951 |
| EGFR | PTK2 | Tyr194 | ALEKKSNyEVLEKDV | phosphorylation up-regulates | 20802513 | SIGNOR-167646 |
| EGFR | RGS16 | Tyr177 | RFLKSPAyRDLAAQA | phosphorylation up-regulates | 11602604 | SIGNOR-111024 |
| EGFR | RGS16 | Tyr168 | TLMEKDSyPRFLKSP | phosphorylation up-regulates | 12588871 | SIGNOR-98267 |
| EGFR | AXL | Tyr779 | ADCLDGLyALMSRCW | phosphorylation up-regulates activity | 27775700 | SIGNOR-279734 |
| EGFR | FUS | – | phosphorylation up-regulates activity | 32678881 | SIGNOR-279168 | |
| EGFR | PARP1 | – | phosphorylation up-regulates activity | 30573522 | SIGNOR-279169 | |
| EGFR | CCDC50 | Tyr279 | TDGEDADyTHFTNQQ | phosphorylation down-regulates activity | 19059208 | SIGNOR-262851 |
| EGFR | PKM | Tyr148 | KITLDNAyMEKCDEN | phosphorylation down-regulates activity | 26759242 | SIGNOR-277197 |
| EGFR | SHC3 | Tyr218 | GDGSDHPyYNSIPSK | phosphorylation up-regulates activity | 11791173 | SIGNOR-273910 |
| EGFR | PLCG1 | Tyr472 | KLAEGSAyEEVPTSM | phosphorylation up-regulates | 1689310 | SIGNOR-20980 |
| EGFR | GSTP1 | Tyr4 | yTVVYFPV | phosphorylation up-regulates | 19254954 | SIGNOR-184383 |
| EGFR | CALM3 | Tyr100 | FDKDGNGyISAAELR | phosphorylation down-regulates | 3415247 | SIGNOR-266335 |
| EGFR | VAV2 | Tyr142 | TENDDDVyRSLEELA | phosphorylation up-regulates | 12454019 | SIGNOR-95972 |
| EGFR | ERRFI1 | Tyr394 | KKVSSTHyYLLPERP | phosphorylation up-regulates activity | 26280531 | SIGNOR-252091 |
| EGFR | CRK | Tyr221 | GGPEPGPyAQPSVNT | phosphorylation down-regulates activity | 9642287 | SIGNOR-251091 |
| EGFR | STAT5B | Tyr725 | AGGGSATyMDQAPSP | phosphorylation up-regulates | 11751923 | SIGNOR-113393 |
| EGFR | STAT1 | – | phosphorylation up-regulates | 14967450 | SIGNOR-121962 | |
| EGFR | GRB2 | Tyr209 | TGMFPRNyVTPVNRN | phosphorylation unknown | 11726515 | SIGNOR-235738 |
| EGFR | PCNA | Tyr211 | QLTFALRyLNFFTKA | phosphorylation up-regulates | 17115032 | SIGNOR-150852 |
| EGFR | KCNJ4 | Tyr234 | YMTQEGEyLPLDQRD | phosphorylation up-regulates activity | 21486282 | SIGNOR-276322 |
| EGFR | GPRC5A | Tyr320 | GDTLYAPySTHFQLQ | phosphorylation down-regulates activity | 25311788 | SIGNOR-278334 |
| EGFR | GAB1 | Tyr589 | SHDSEENyVPMNPNL | phosphorylation up-regulates activity | 9890893 | SIGNOR-236416 |
| EGFR | ASAP3 | Tyr34 | FAAKMPRyRGAALAR | phosphorylation up-regulates activity | 23776207 | SIGNOR-272234 |
| EGFR | EGFR | Tyr1092 | TFLPVPEyINQSVPK | phosphorylation up-regulates activity | 10653583 | SIGNOR-236479 |
| EGFR | SCAMP1 | Tyr37 | VPPGLDEyNPFSDSR | phosphorylation up-regulates activity | 9658162 | SIGNOR-262857 |
| EGFR | GLUD1 | Tyr135 | SWEVIEGyRAQHSQH | phosphorylation up-regulates activity | 36516759 | SIGNOR-279706 |
| EGFR | SHC3 | Tyr219 | DGSDHPYyNSIPSKM | phosphorylation up-regulates activity | 11791173 | SIGNOR-273912 |
| EGFR | AGO2 | Tyr393 | ASFNTDPyVREFGIM | phosphorylation up-regulates activity | 25137592 | SIGNOR-278931 |
| EGFR | EGFR | Tyr1016 | DVVDADEyLIPQQGF | phosphorylation up-regulates activity | 16122376 | SIGNOR-236527 |
| EGFR | TLR3 | Tyr858 | FLEEIPDyKLNHALC | phosphorylation up-regulates activity | 25022196 | SIGNOR-278932 |
| EGFR | HGS | Tyr329 | IDPELARyLNRNYWE | phosphorylation up-regulates | 12953068 | SIGNOR-86689 |
| EGFR | LYN | Tyr32 | RNTERTIyVRDPTSN | phosphorylation up-regulates activity | 23764002 | SIGNOR-279369 |
| EGFR | EGFR | Tyr1092 | TFLPVPEyINQSVPK | phosphorylation up-regulates activity | 16122376 | SIGNOR-236523 |
| EGFR | ANXA1 | Tyr21 | IENEEQEyVQTVKSS | phosphorylation up-regulates | 24103589 | SIGNOR-202776 |
| EGFR | EZR | Tyr146 | KEVHKSGyLSSERLI | phosphorylation unknown | 15647376 | SIGNOR-133219 |
| EGFR | IKBKE | Tyr153 | GEEGQSIyKLTDFGA | phosphorylation up-regulates activity | 27287717 | SIGNOR-278223 |
| EGFR | STAT1 | – | phosphorylation up-regulates | 22693070 | SIGNOR-235689 | |
| EGFR | SPRED1 | Ser105 | KFGLTFQsPADARAF | phosphorylation down-regulates activity | 32697994 | SIGNOR-273638 |
| EGFR | EGFR | Tyr1172 | ISLDNPDyQQDFFPK | phosphorylation up-regulates activity | 10653583 | SIGNOR-236467 |
| EGFR | STAT3 | – | phosphorylation up-regulates activity | 14967450 | SIGNOR-121965 | |
| EGFR | EGFR | Tyr1197 | STAENAEyLRVAPQS | phosphorylation up-regulates activity | 10653583 | SIGNOR-236471 |
| EGFR | VAV2 | Tyr172 | EDGGDDIyEDIIKVE | phosphorylation up-regulates | 12454019 | SIGNOR-95980 |
| EGFR | ABCA1 | Ser2054 | GGNKRKLsTAMALIG | phosphorylation down-regulates quantity by destabilization | 12196520 | SIGNOR-264419 |
| EGFR | SHC3 | Tyr283 | RQGSSDIySTPEGKL | phosphorylation up-regulates activity | 11791173 | SIGNOR-273911 |
| EGFR | GPRC5A | Tyr317 | EETGDTLyAPYSTHF | phosphorylation down-regulates activity | 25311788 | SIGNOR-278333 |
| EGFR | GPRC5A | Tyr347 | AHAWPSPyKDYEVKK | phosphorylation down-regulates activity | 25311788 | SIGNOR-278335 |
| EGFR | IKBKE | Tyr153 | GEEGQSIyKLTDFGA | phosphorylation up-regulates activity | 27287717 | SIGNOR-277242 |
| EGFR | BECN1 | Tyr233 | EAQYQREySEFKRQQ | phosphorylation down-regulates activity | 24034250 | SIGNOR-278357 |
| EGFR | PELI1 | Tyr154 | PPFTARIyAAGFDSS | phosphorylation up-regulates activity | 36841821 | SIGNOR-277873 |
| EGFR | SOX2 | Tyr277 | LRDMISMyLPGAEVP | phosphorylation up-regulates quantity by stabilization | 31823521 | SIGNOR-279036 |
| EGFR | SHC3 | Tyr301 | PTGEAPTyVNTQQIP | phosphorylation up-regulates activity | 11791173 | SIGNOR-273922 |
| EGFR | PLCG1 | Tyr1253 | EGSFESRyQQPFEDF | phosphorylation up-regulates | 1689310 | SIGNOR-20976 |
| EGFR | EGFR | Tyr869 | LGAEEKEyHAEGGKV | phosphorylation up-regulates activity | 16122376 | SIGNOR-235956 |
| EGFR | EGFR | Tyr1016 | DVVDADEyLIPQQGF | phosphorylation up-regulates activity | 10653583 | SIGNOR-236475 |
| EGFR | EPS15 | Tyr849 | NFANFSAyPSEEDMI | phosphorylation up-regulates | 24269888 | SIGNOR-203311 |
| EGFR | MUC1 | Tyr1229 | SSTDRSPyEKVSAGN | phosphorylation up-regulates activity | 11483589 | SIGNOR-109538 |
| EGFR | GSTP1 | Tyr8 | MPPYTVVyFPVRGRC | phosphorylation up-regulates | 19254954 | SIGNOR-184387 |
| EGFR | EGFR | Tyr1110 | GSVQNPVyHNQPLNP | phosphorylation up-regulates activity | 16122376 | SIGNOR-236516 |
| EGFR | GSTP1 | Tyr199 | AFLASPEyVNLPING | phosphorylation up-regulates | 19254954 | SIGNOR-184379 |
| EGFR | PLD2 | Tyr179 | RLLTMSFyRNYHAMT | phosphorylation up-regulates activity | 9837959 | SIGNOR-251095 |
| EGFR | IKBKE | Tyr179 | SVYGTEEyLHPDMYE | phosphorylation up-regulates activity | 27287717 | SIGNOR-277243 |
| EGFR | PKIA | Tyr8 | MTDVETTyADFIASG | phosphorylation up-regulates | 1956339 | SIGNOR-22455 |
| EGFR | IKBKE | Tyr179 | SVYGTEEyLHPDMYE | phosphorylation up-regulates activity | 27287717 | SIGNOR-278222 |
| EGFR | CCDC50 | Tyr217 | MAEEKKAyKKAKERE | phosphorylation down-regulates activity | 19059208 | SIGNOR-262850 |
| EGFR | HGS | Tyr334 | ARYLNRNyWEKKQEE | phosphorylation up-regulates activity | 12953068 | SIGNOR-100246 |
| EGFR | CALM1 | Tyr100 | FDKDGNGyISAAELR | phosphorylation down-regulates | 7925415 | SIGNOR-34691 |
| EGFR | CTNND1 | Tyr228 | YPGGSDNyGSLSRVT | phosphorylation unknown | 14996911 | SIGNOR-251092 |
| EGFR | ERBB3 | Tyr1276 | GGGPGGDyAAMGACP | phosphorylation up-regulates | 7929151 | SIGNOR-34748 |
| EGFR | EGFR | Tyr1069 | EDSFLQRySSDPTGA | phosphorylation up-regulates activity | 10635327 | SIGNOR-251093 |
| EGFR | LRRK1 | Tyr971 | TQQTEEQyFQFLAKF | phosphorylation down-regulates activity | 22337768 | SIGNOR-262856 |
| EGFR | GNAI1 | Tyr155 | LNDSAAYyLNDLDRI | phosphorylation up-regulates activity | 33139573 | SIGNOR-277226 |
| EGFR | SQSTM1 | Tyr433 | AALDTIQySKHPPPL | phosphorylation down-regulates activity | 31931029 | SIGNOR-277500 |
| EGFR | HDAC6 | Tyr570 | SSNFDSIyICPSTFA | phosphorylation down-regulates | 20029029 | SIGNOR-162431 |
| EGFR | GAB1 | Tyr307 | MRHVSISyDIPPTPG | phosphorylation up-regulates activity | 10734310 | SIGNOR-233233 |
| EGFR | GNAI1 | Tyr154 | QLNDSAAyYLNDLDR | phosphorylation up-regulates activity | 33139573 | SIGNOR-277227 |
| EGFR | ATM | Tyr370 | SLEISQSyTTTQRES | phosphorylation up-regulates activity | 25601159 | SIGNOR-276872 |
| EGFR | SCAMP3 | Tyr41 | QYATLDVyNPFETRE | phosphorylation up-regulates activity | 9658162 | SIGNOR-262858 |
| EGFR | NIBAN2 | Tyr593 | PIDWGEEySNSGGGG | phosphorylation up-regulates activity | 26721396 | SIGNOR-273637 |
| EGFR | EPB41 | Tyr660 | RLDGENIyIRHSNLM | phosphorylation down-regulates | 1647028 | SIGNOR-20452 |
| EGFR | EZR | Tyr354 | LMLRLQDyEEKTKKA | phosphorylation up-regulates | 15647376 | SIGNOR-133215 |
| EGFR | GAB1 | Tyr472 | EPIQEANyVPMTPGT | phosphorylation up-regulates activity | 9890893 | SIGNOR-236412 |
| EGFR | VAV2 | Tyr159 | HDLGEDIyDCVPCED | phosphorylation up-regulates | 12454019 | SIGNOR-95976 |
| EGFR | GAB1 | Tyr406 | DASSQDCyDIPRAFP | phosphorylation up-regulates | 9890893 | SIGNOR-236396 |
| EGFR | SCAMP3 | Tyr41 | QYATLDVyNPFETRE | phosphorylation unknown | 9658162 | SIGNOR-251096 |
| EGFR | GAB1 | Tyr659 | VADERVDyVVVDQQK | phosphorylation up-regulates | 9890893 | SIGNOR-236404 |
| EGFR | GNAI1 | Tyr320 | RKDTKEIyTHFTCAT | phosphorylation up-regulates activity | 33139573 | SIGNOR-277228 |
| EGFR | CCDC50 | Tyr304 | SSHKGFHyKH | phosphorylation down-regulates activity | 19059208 | SIGNOR-262852 |
| EGFR | KCND3 | Tyr136 | GDCCYEEyKDRKREN | phosphorylation up-regulates activity | 22198508 | SIGNOR-275549 |
| EGFR | KCNN1 | Tyr109 | KRKRLSDyALIFGMF | phosphorylation up-regulates activity | 23496660 | SIGNOR-276490 |
| EGFR | JAK1/STAT1/STAT3 | – | phosphorylation up-regulates activity | 15284024 | SIGNOR-252088 | |
| EGFR | EGFR | Tyr1110 | GSVQNPVyHNQPLNP | phosphorylation up-regulates activity | 10653583 | SIGNOR-236483 |
| EGFR | STAT3 | – | phosphorylation up-regulates activity | 22693070 | SIGNOR-235692 | |
| EGFR | GAB1 | Tyr447 | SEELDENyVPMNPNS | phosphorylation up-regulates | 9890893 | SIGNOR-236420 |
| EGFR | PTPN1 | Tyr66 | LHQEDNDyINASLIK | phosphorylation up-regulates | 9355745 | SIGNOR-52950 |
| EGFR | STAT5B | Tyr743 | PQAHYNMyPQNPDSV | phosphorylation up-regulates | 11751923 | SIGNOR-113401 |
| EGFR | KCND3 | Tyr136 | GDCCYEEyKDRKREN | phosphorylation up-regulates activity | 22198508 | SIGNOR-276397 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EGFR | phosphorylation up-regulates → | EGFR PTyr1172 | phosphorylation up-regulates → | EGFR | 16122376 | SIGNOR-236531 |
| EGFR | phosphorylation up-regulates → | PPARG PTyr102 | phosphorylation down-regulates ⊣ | PPARG | 26718225 | SIGNOR-277190 |
| EGFR | phosphorylation up-regulates → | TRIP13 PTyr56 | phosphorylation up-regulates → | TRIP13 | 32860853 | SIGNOR-265083 |
| EGFR | phosphorylation up-regulates → | CALM1 PTyr100 | phosphorylation down-regulates ⊣ | CALM1 | 3415247 | SIGNOR-24778 |
| EGFR | phosphorylation up-regulates → | PELI1 PThr264 | phosphorylation up-regulates → | PELI1 | 36841821 | SIGNOR-277874 |
| EGFR | phosphorylation up-regulates → | CBL PTyr371 | phosphorylation up-regulates → | CBL | 29920512 | SIGNOR-279998 |
| EGFR | phosphorylation up-regulates → | ERBB2 PTyr1248 | phosphorylation up-regulates → | ERBB2 | 12354693 | SIGNOR-251094 |
| EGFR | phosphorylation up-regulates → | RASA1 PTyr460 | phosphorylation down-regulates ⊣ | RASA1 | 1850098 | SIGNOR-21875 |
| EGFR | phosphorylation up-regulates → | USP8 PTyr810 | phosphorylation up-regulates → | USP8 | 29472535 | SIGNOR-279038 |
| EGFR | phosphorylation up-regulates → | GRK2 PTyr13 | phosphorylation up-regulates → | GRK2 | 23904266 | SIGNOR-279368 |
| EGFR | phosphorylation up-regulates → | ERBB3 PTyr1289 | phosphorylation up-regulates → | ERBB3 | 7929151 | SIGNOR-34752 |
| EGFR | phosphorylation up-regulates → | GPRC5A PTyr350 | phosphorylation down-regulates ⊣ | GPRC5A | 25311788 | SIGNOR-278336 |
| EGFR | phosphorylation up-regulates → | STAT5B PTyr740 | phosphorylation up-regulates → | STAT5B | 11751923 | SIGNOR-113397 |
| EGFR | phosphorylation up-regulates → | PLCG1 PTyr783 | phosphorylation up-regulates → | PLCG1 | 9176240 | SIGNOR-48872 |
| EGFR | phosphorylation up-regulates → | STAM2 PTyr192 | phosphorylation down-regulates ⊣ | STAM2 | 11687594 | SIGNOR-251097 |
| EGFR | phosphorylation up-regulates → | PTK2 PTyr5 | phosphorylation up-regulates → | PTK2 | 20802513 | SIGNOR-167650 |
| EGFR | phosphorylation up-regulates → | STAT5B PTyr699 | phosphorylation up-regulates → | STAT5B | 11751923 | SIGNOR-251098 |
| EGFR | phosphorylation up-regulates → | ZNRF1 PTyr103 | phosphorylation up-regulates → | ZNRF1 | 26572619 | SIGNOR-279522 |
| EGFR | phosphorylation up-regulates → | CTNNB1 PTyr654 | phosphorylation up-regulates → | CTNNB1 | 25164010 | SIGNOR-278308 |
| EGFR | phosphorylation up-regulates → | PLCG1 PTyr771 | phosphorylation up-regulates → | PLCG1 | 1689310 | SIGNOR-20984 |
| EGFR | phosphorylation up-regulates → | USP8 PTyr717 | phosphorylation up-regulates → | USP8 | 29472535 | SIGNOR-279037 |
| EGFR | phosphorylation up-regulates → | GAB1 PTyr285 | phosphorylation up-regulates → | GAB1 | 9890893 | SIGNOR-236400 |
| EGFR | phosphorylation up-regulates → | CTNNB1 PTyr142 | phosphorylation up-regulates → | CTNNB1 | 22558232 | SIGNOR-278309 |
| EGFR | phosphorylation up-regulates → | DOCK1 PSer1250 | phosphorylation up-regulates → | DOCK1 | 23728337 | SIGNOR-279329 |
| EGFR | phosphorylation up-regulates → | PTPN11 PTyr542 | phosphorylation up-regulates → | PTPN11 | 19427850 | SIGNOR-279460 |
| EGFR | phosphorylation up-regulates → | CALM2 PTyr100 | phosphorylation down-regulates ⊣ | CALM2 | 3415247 | SIGNOR-266319 |
| EGFR | phosphorylation up-regulates → | GAB1 PTyr373 | phosphorylation up-regulates → | GAB1 | 9890893 | SIGNOR-236408 |
| EGFR | phosphorylation up-regulates → | GAB1 PTyr627 | phosphorylation up-regulates → | GAB1 | 9890893 | SIGNOR-236392 |
| EGFR | phosphorylation up-regulates → | EGFR PTyr869 | phosphorylation up-regulates → | EGFR | 10653583 | SIGNOR-236487 |
| EGFR | phosphorylation up-regulates → | EGFR PTyr1197 | phosphorylation up-regulates → | EGFR | 16122376 | SIGNOR-235951 |
| EGFR | phosphorylation up-regulates → | PTK2 PTyr194 | phosphorylation up-regulates → | PTK2 | 20802513 | SIGNOR-167646 |
| EGFR | phosphorylation up-regulates → | RGS16 PTyr177 | phosphorylation up-regulates → | RGS16 | 11602604 | SIGNOR-111024 |
| EGFR | phosphorylation up-regulates → | RGS16 PTyr168 | phosphorylation up-regulates → | RGS16 | 12588871 | SIGNOR-98267 |
| EGFR | phosphorylation up-regulates → | AXL PTyr779 | phosphorylation up-regulates → | AXL | 27775700 | SIGNOR-279734 |
| EGFR | phosphorylation up-regulates → | CCDC50 PTyr279 | phosphorylation down-regulates ⊣ | CCDC50 | 19059208 | SIGNOR-262851 |
| EGFR | phosphorylation up-regulates → | PKM PTyr148 | phosphorylation down-regulates ⊣ | PKM | 26759242 | SIGNOR-277197 |
| EGFR | phosphorylation up-regulates → | SHC3 PTyr218 | phosphorylation up-regulates → | SHC3 | 11791173 | SIGNOR-273910 |
| EGFR | phosphorylation up-regulates → | PLCG1 PTyr472 | phosphorylation up-regulates → | PLCG1 | 1689310 | SIGNOR-20980 |
| EGFR | phosphorylation up-regulates → | GSTP1 PTyr4 | phosphorylation up-regulates → | GSTP1 | 19254954 | SIGNOR-184383 |
| EGFR | phosphorylation up-regulates → | CALM3 PTyr100 | phosphorylation down-regulates ⊣ | CALM3 | 3415247 | SIGNOR-266335 |
| EGFR | phosphorylation up-regulates → | VAV2 PTyr142 | phosphorylation up-regulates → | VAV2 | 12454019 | SIGNOR-95972 |
| EGFR | phosphorylation up-regulates → | ERRFI1 PTyr394 | phosphorylation up-regulates → | ERRFI1 | 26280531 | SIGNOR-252091 |
| EGFR | phosphorylation up-regulates → | CRK PTyr221 | phosphorylation down-regulates ⊣ | CRK | 9642287 | SIGNOR-251091 |
| EGFR | phosphorylation up-regulates → | STAT5B PTyr725 | phosphorylation up-regulates → | STAT5B | 11751923 | SIGNOR-113393 |
| EGFR | phosphorylation up-regulates → | GRB2 PTyr209 | phosphorylation down-regulates ⊣ | GRB2 | 11726515 | SIGNOR-235738 |
| EGFR | phosphorylation up-regulates → | PCNA PTyr211 | phosphorylation up-regulates → | PCNA | 17115032 | SIGNOR-150852 |
| EGFR | phosphorylation up-regulates → | KCNJ4 PTyr234 | phosphorylation up-regulates → | KCNJ4 | 21486282 | SIGNOR-276322 |
| EGFR | phosphorylation up-regulates → | GPRC5A PTyr320 | phosphorylation down-regulates ⊣ | GPRC5A | 25311788 | SIGNOR-278334 |
| EGFR | phosphorylation up-regulates → | GAB1 PTyr589 | phosphorylation up-regulates → | GAB1 | 9890893 | SIGNOR-236416 |
| EGFR | phosphorylation up-regulates → | ASAP3 PTyr34 | phosphorylation up-regulates → | ASAP3 | 23776207 | SIGNOR-272234 |
| EGFR | phosphorylation up-regulates → | EGFR PTyr1092 | phosphorylation up-regulates → | EGFR | 10653583 | SIGNOR-236479 |
| EGFR | phosphorylation up-regulates → | SCAMP1 PTyr37 | phosphorylation up-regulates → | SCAMP1 | 9658162 | SIGNOR-262857 |
| EGFR | phosphorylation up-regulates → | GLUD1 PTyr135 | phosphorylation up-regulates → | GLUD1 | 36516759 | SIGNOR-279706 |
| EGFR | phosphorylation up-regulates → | SHC3 PTyr219 | phosphorylation up-regulates → | SHC3 | 11791173 | SIGNOR-273912 |
| EGFR | phosphorylation up-regulates → | AGO2 PTyr393 | phosphorylation up-regulates → | AGO2 | 25137592 | SIGNOR-278931 |
| EGFR | phosphorylation up-regulates → | EGFR PTyr1016 | phosphorylation up-regulates → | EGFR | 16122376 | SIGNOR-236527 |
| EGFR | phosphorylation up-regulates → | TLR3 PTyr858 | phosphorylation up-regulates → | TLR3 | 25022196 | SIGNOR-278932 |
| EGFR | phosphorylation up-regulates → | HGS PTyr329 | phosphorylation up-regulates → | HGS | 12953068 | SIGNOR-86689 |
| EGFR | phosphorylation up-regulates → | LYN PTyr32 | phosphorylation up-regulates → | LYN | 23764002 | SIGNOR-279369 |
| EGFR | phosphorylation up-regulates → | EGFR PTyr1092 | phosphorylation up-regulates → | EGFR | 16122376 | SIGNOR-236523 |
| EGFR | phosphorylation up-regulates → | ANXA1 PTyr21 | phosphorylation up-regulates → | ANXA1 | 24103589 | SIGNOR-202776 |
| EGFR | phosphorylation up-regulates → | EZR PTyr146 | phosphorylation down-regulates ⊣ | EZR | 15647376 | SIGNOR-133219 |
| EGFR | phosphorylation up-regulates → | IKBKE PTyr153 | phosphorylation up-regulates → | IKBKE | 27287717 | SIGNOR-278223 |
| EGFR | phosphorylation up-regulates → | SPRED1 PSer105 | phosphorylation down-regulates ⊣ | SPRED1 | 32697994 | SIGNOR-273638 |
| EGFR | phosphorylation up-regulates → | EGFR PTyr1172 | phosphorylation up-regulates → | EGFR | 10653583 | SIGNOR-236467 |
| EGFR | phosphorylation up-regulates → | EGFR PTyr1197 | phosphorylation up-regulates → | EGFR | 10653583 | SIGNOR-236471 |
| EGFR | phosphorylation up-regulates → | VAV2 PTyr172 | phosphorylation up-regulates → | VAV2 | 12454019 | SIGNOR-95980 |
| EGFR | phosphorylation up-regulates → | ABCA1 PSer2054 | phosphorylation down-regulates ⊣ | ABCA1 | 12196520 | SIGNOR-264419 |
| EGFR | phosphorylation up-regulates → | SHC3 PTyr283 | phosphorylation up-regulates → | SHC3 | 11791173 | SIGNOR-273911 |
| EGFR | phosphorylation up-regulates → | GPRC5A PTyr317 | phosphorylation down-regulates ⊣ | GPRC5A | 25311788 | SIGNOR-278333 |
| EGFR | phosphorylation up-regulates → | GPRC5A PTyr347 | phosphorylation down-regulates ⊣ | GPRC5A | 25311788 | SIGNOR-278335 |
| EGFR | phosphorylation up-regulates → | IKBKE PTyr153 | phosphorylation up-regulates → | IKBKE | 27287717 | SIGNOR-277242 |
| EGFR | phosphorylation up-regulates → | BECN1 PTyr233 | phosphorylation down-regulates ⊣ | BECN1 | 24034250 | SIGNOR-278357 |
| EGFR | phosphorylation up-regulates → | PELI1 PTyr154 | phosphorylation up-regulates → | PELI1 | 36841821 | SIGNOR-277873 |
| EGFR | phosphorylation up-regulates → | SOX2 PTyr277 | phosphorylation up-regulates → | SOX2 | 31823521 | SIGNOR-279036 |
| EGFR | phosphorylation up-regulates → | SHC3 PTyr301 | phosphorylation up-regulates → | SHC3 | 11791173 | SIGNOR-273922 |
| EGFR | phosphorylation up-regulates → | PLCG1 PTyr1253 | phosphorylation up-regulates → | PLCG1 | 1689310 | SIGNOR-20976 |
| EGFR | phosphorylation up-regulates → | EGFR PTyr869 | phosphorylation up-regulates → | EGFR | 16122376 | SIGNOR-235956 |
| EGFR | phosphorylation up-regulates → | EGFR PTyr1016 | phosphorylation up-regulates → | EGFR | 10653583 | SIGNOR-236475 |
| EGFR | phosphorylation up-regulates → | EPS15 PTyr849 | phosphorylation up-regulates → | EPS15 | 24269888 | SIGNOR-203311 |
| EGFR | phosphorylation up-regulates → | MUC1 PTyr1229 | phosphorylation up-regulates → | MUC1 | 11483589 | SIGNOR-109538 |
| EGFR | phosphorylation up-regulates → | GSTP1 PTyr8 | phosphorylation up-regulates → | GSTP1 | 19254954 | SIGNOR-184387 |
| EGFR | phosphorylation up-regulates → | EGFR PTyr1110 | phosphorylation up-regulates → | EGFR | 16122376 | SIGNOR-236516 |
| EGFR | phosphorylation up-regulates → | GSTP1 PTyr199 | phosphorylation up-regulates → | GSTP1 | 19254954 | SIGNOR-184379 |
| EGFR | phosphorylation up-regulates → | PLD2 PTyr179 | phosphorylation up-regulates → | PLD2 | 9837959 | SIGNOR-251095 |
| EGFR | phosphorylation up-regulates → | IKBKE PTyr179 | phosphorylation up-regulates → | IKBKE | 27287717 | SIGNOR-277243 |
| EGFR | phosphorylation up-regulates → | PKIA PTyr8 | phosphorylation up-regulates → | PKIA | 1956339 | SIGNOR-22455 |
| EGFR | phosphorylation up-regulates → | IKBKE PTyr179 | phosphorylation up-regulates → | IKBKE | 27287717 | SIGNOR-278222 |
| EGFR | phosphorylation up-regulates → | CCDC50 PTyr217 | phosphorylation down-regulates ⊣ | CCDC50 | 19059208 | SIGNOR-262850 |
| EGFR | phosphorylation up-regulates → | HGS PTyr334 | phosphorylation up-regulates → | HGS | 12953068 | SIGNOR-100246 |
| EGFR | phosphorylation up-regulates → | CALM1 PTyr100 | phosphorylation down-regulates ⊣ | CALM1 | 7925415 | SIGNOR-34691 |
| EGFR | phosphorylation up-regulates → | CTNND1 PTyr228 | phosphorylation down-regulates ⊣ | CTNND1 | 14996911 | SIGNOR-251092 |
| EGFR | phosphorylation up-regulates → | ERBB3 PTyr1276 | phosphorylation up-regulates → | ERBB3 | 7929151 | SIGNOR-34748 |
| EGFR | phosphorylation up-regulates → | EGFR PTyr1069 | phosphorylation up-regulates → | EGFR | 10635327 | SIGNOR-251093 |
| EGFR | phosphorylation up-regulates → | LRRK1 PTyr971 | phosphorylation down-regulates ⊣ | LRRK1 | 22337768 | SIGNOR-262856 |
| EGFR | phosphorylation up-regulates → | GNAI1 PTyr155 | phosphorylation up-regulates → | GNAI1 | 33139573 | SIGNOR-277226 |
| EGFR | phosphorylation up-regulates → | SQSTM1 PTyr433 | phosphorylation down-regulates ⊣ | SQSTM1 | 31931029 | SIGNOR-277500 |
| EGFR | phosphorylation up-regulates → | HDAC6 PTyr570 | phosphorylation down-regulates ⊣ | HDAC6 | 20029029 | SIGNOR-162431 |
| EGFR | phosphorylation up-regulates → | GAB1 PTyr307 | phosphorylation up-regulates → | GAB1 | 10734310 | SIGNOR-233233 |
| EGFR | phosphorylation up-regulates → | GNAI1 PTyr154 | phosphorylation up-regulates → | GNAI1 | 33139573 | SIGNOR-277227 |
| EGFR | phosphorylation up-regulates → | ATM PTyr370 | phosphorylation up-regulates → | ATM | 25601159 | SIGNOR-276872 |
| EGFR | phosphorylation up-regulates → | SCAMP3 PTyr41 | phosphorylation up-regulates → | SCAMP3 | 9658162 | SIGNOR-262858 |
| EGFR | phosphorylation up-regulates → | NIBAN2 PTyr593 | phosphorylation up-regulates → | NIBAN2 | 26721396 | SIGNOR-273637 |
| EGFR | phosphorylation up-regulates → | EPB41 PTyr660 | phosphorylation down-regulates ⊣ | EPB41 | 1647028 | SIGNOR-20452 |
| EGFR | phosphorylation up-regulates → | EZR PTyr354 | phosphorylation up-regulates → | EZR | 15647376 | SIGNOR-133215 |
| EGFR | phosphorylation up-regulates → | GAB1 PTyr472 | phosphorylation up-regulates → | GAB1 | 9890893 | SIGNOR-236412 |
| EGFR | phosphorylation up-regulates → | VAV2 PTyr159 | phosphorylation up-regulates → | VAV2 | 12454019 | SIGNOR-95976 |
| EGFR | phosphorylation up-regulates → | GAB1 PTyr406 | phosphorylation up-regulates → | GAB1 | 9890893 | SIGNOR-236396 |
| EGFR | phosphorylation up-regulates → | SCAMP3 PTyr41 | phosphorylation down-regulates ⊣ | SCAMP3 | 9658162 | SIGNOR-251096 |
| EGFR | phosphorylation up-regulates → | GAB1 PTyr659 | phosphorylation up-regulates → | GAB1 | 9890893 | SIGNOR-236404 |
| EGFR | phosphorylation up-regulates → | GNAI1 PTyr320 | phosphorylation up-regulates → | GNAI1 | 33139573 | SIGNOR-277228 |
| EGFR | phosphorylation up-regulates → | CCDC50 PTyr304 | phosphorylation down-regulates ⊣ | CCDC50 | 19059208 | SIGNOR-262852 |
| EGFR | phosphorylation up-regulates → | KCND3 PTyr136 | phosphorylation up-regulates → | KCND3 | 22198508 | SIGNOR-275549 |
| EGFR | phosphorylation up-regulates → | KCNN1 PTyr109 | phosphorylation up-regulates → | KCNN1 | 23496660 | SIGNOR-276490 |
| EGFR | phosphorylation up-regulates → | EGFR PTyr1110 | phosphorylation up-regulates → | EGFR | 10653583 | SIGNOR-236483 |
| EGFR | phosphorylation up-regulates → | GAB1 PTyr447 | phosphorylation up-regulates → | GAB1 | 9890893 | SIGNOR-236420 |
| EGFR | phosphorylation up-regulates → | PTPN1 PTyr66 | phosphorylation up-regulates → | PTPN1 | 9355745 | SIGNOR-52950 |
| EGFR | phosphorylation up-regulates → | STAT5B PTyr743 | phosphorylation up-regulates → | STAT5B | 11751923 | SIGNOR-113401 |
| EGFR | phosphorylation up-regulates → | KCND3 PTyr136 | phosphorylation up-regulates → | KCND3 | 22198508 | SIGNOR-276397 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| EGFR | phosphorylation → up-regulates activity | EGFR | SIGNOR-236531 |
| EGFR | phosphorylation down-regulates quantity by destabilization | PPARG | SIGNOR-277190 |
| EGFR | phosphorylation → up-regulates quantity | TRIP13 | SIGNOR-265083 |
| EGFR | phosphorylation down-regulates | CALM1 | SIGNOR-24778 |
| EGFR | phosphorylation → up-regulates activity | PELI1 | SIGNOR-277874 |
| EGFR | phosphorylation → up-regulates activity | ACAT1 | SIGNOR-279996 |
| EGFR | phosphorylation → up-regulates activity | CBL | SIGNOR-279998 |
| EGFR | phosphorylation → up-regulates activity | MST1R | SIGNOR-280000 |
| EGFR | phosphorylation → up-regulates activity | NOTCH3 | SIGNOR-280002 |
| EGFR | phosphorylation → up-regulates activity | ERBB2 | SIGNOR-251094 |
| EGFR | phosphorylation → unknown | RASA1 | SIGNOR-21875 |
| EGFR | phosphorylation → up-regulates | ESR1 | SIGNOR-115734 |
| EGFR | phosphorylation → up-regulates activity | USP8 | SIGNOR-279038 |
| EGFR | phosphorylation → up-regulates activity | GRK2 | SIGNOR-279368 |
| EGFR | phosphorylation → up-regulates | ERBB3 | SIGNOR-34752 |
| EGFR | phosphorylation → down-regulates activity | GPRC5A | SIGNOR-278336 |
| EGFR | phosphorylation → up-regulates | STAT5B | SIGNOR-113397 |
| EGFR | phosphorylation → up-regulates | PLCG1 | SIGNOR-48872 |
| EGFR | phosphorylation → unknown | STAM2 | SIGNOR-251097 |
| EGFR | phosphorylation → up-regulates | PTK2 | SIGNOR-167650 |
| EGFR | phosphorylation → up-regulates activity | STAT5B | SIGNOR-251098 |
| EGFR | phosphorylation → up-regulates activity | ZNRF1 | SIGNOR-279522 |
| EGFR | phosphorylation → up-regulates activity | CTNNB1 | SIGNOR-278308 |
| EGFR | phosphorylation → up-regulates | PLCG1 | SIGNOR-20984 |
| EGFR | phosphorylation → up-regulates activity | USP8 | SIGNOR-279037 |
| EGFR | phosphorylation → up-regulates | GAB1 | SIGNOR-236400 |
| EGFR | phosphorylation → up-regulates activity | CTNNB1 | SIGNOR-278309 |
| EGFR | phosphorylation → up-regulates activity | DOCK1 | SIGNOR-279329 |
| EGFR | phosphorylation → up-regulates activity | PTPN11 | SIGNOR-279460 |
| EGFR | phosphorylation down-regulates | CALM2 | SIGNOR-266319 |
| EGFR | phosphorylation → up-regulates activity | GAB1 | SIGNOR-236408 |
| EGFR | phosphorylation → up-regulates | PIK3C2B | SIGNOR-77195 |
| EGFR | phosphorylation → up-regulates | GAB1 | SIGNOR-236392 |
| EGFR | phosphorylation → up-regulates activity | EGFR | SIGNOR-236487 |
| EGFR | phosphorylation → up-regulates activity | EGFR | SIGNOR-235951 |
| EGFR | phosphorylation → up-regulates | PTK2 | SIGNOR-167646 |
| EGFR | phosphorylation → up-regulates | RGS16 | SIGNOR-111024 |
| EGFR | phosphorylation → up-regulates | RGS16 | SIGNOR-98267 |
| EGFR | phosphorylation → up-regulates activity | AXL | SIGNOR-279734 |
| EGFR | phosphorylation → up-regulates activity | FUS | SIGNOR-279168 |
| EGFR | phosphorylation → up-regulates activity | PARP1 | SIGNOR-279169 |
| EGFR | phosphorylation → down-regulates activity | CCDC50 | SIGNOR-262851 |
| EGFR | phosphorylation → down-regulates activity | PKM | SIGNOR-277197 |
| EGFR | phosphorylation → up-regulates activity | SHC3 | SIGNOR-273910 |
| EGFR | phosphorylation → up-regulates | PLCG1 | SIGNOR-20980 |
| EGFR | phosphorylation → up-regulates | GSTP1 | SIGNOR-184383 |
| EGFR | phosphorylation down-regulates | CALM3 | SIGNOR-266335 |
| EGFR | phosphorylation → up-regulates | VAV2 | SIGNOR-95972 |
| EGFR | phosphorylation → up-regulates activity | ERRFI1 | SIGNOR-252091 |
| EGFR | phosphorylation → down-regulates activity | CRK | SIGNOR-251091 |
| EGFR | phosphorylation → up-regulates | STAT5B | SIGNOR-113393 |
| EGFR | phosphorylation → up-regulates | STAT1 | SIGNOR-121962 |
| EGFR | phosphorylation → unknown | GRB2 | SIGNOR-235738 |
| EGFR | phosphorylation → up-regulates | PCNA | SIGNOR-150852 |
| EGFR | phosphorylation → up-regulates activity | KCNJ4 | SIGNOR-276322 |
| EGFR | phosphorylation → down-regulates activity | GPRC5A | SIGNOR-278334 |
| EGFR | phosphorylation → up-regulates activity | GAB1 | SIGNOR-236416 |
| EGFR | phosphorylation → up-regulates activity | ASAP3 | SIGNOR-272234 |
| EGFR | phosphorylation → up-regulates activity | EGFR | SIGNOR-236479 |
| EGFR | phosphorylation → up-regulates activity | SCAMP1 | SIGNOR-262857 |
| EGFR | phosphorylation → up-regulates activity | GLUD1 | SIGNOR-279706 |
| EGFR | phosphorylation → up-regulates activity | SHC3 | SIGNOR-273912 |
| EGFR | phosphorylation → up-regulates activity | AGO2 | SIGNOR-278931 |
| EGFR | phosphorylation → up-regulates activity | EGFR | SIGNOR-236527 |
| EGFR | phosphorylation → up-regulates activity | TLR3 | SIGNOR-278932 |
| EGFR | phosphorylation → up-regulates | HGS | SIGNOR-86689 |
| EGFR | phosphorylation → up-regulates activity | LYN | SIGNOR-279369 |
| EGFR | phosphorylation → up-regulates activity | EGFR | SIGNOR-236523 |
| EGFR | phosphorylation → up-regulates | ANXA1 | SIGNOR-202776 |
| EGFR | phosphorylation → unknown | EZR | SIGNOR-133219 |
| EGFR | phosphorylation → up-regulates activity | IKBKE | SIGNOR-278223 |
| EGFR | phosphorylation → up-regulates | STAT1 | SIGNOR-235689 |
| EGFR | phosphorylation → down-regulates activity | SPRED1 | SIGNOR-273638 |
| EGFR | phosphorylation → up-regulates activity | EGFR | SIGNOR-236467 |
| EGFR | phosphorylation → up-regulates activity | STAT3 | SIGNOR-121965 |
| EGFR | phosphorylation → up-regulates activity | EGFR | SIGNOR-236471 |
| EGFR | phosphorylation → up-regulates | VAV2 | SIGNOR-95980 |
| EGFR | phosphorylation down-regulates quantity by destabilization | ABCA1 | SIGNOR-264419 |
| EGFR | phosphorylation → up-regulates activity | SHC3 | SIGNOR-273911 |
| EGFR | phosphorylation → down-regulates activity | GPRC5A | SIGNOR-278333 |
| EGFR | phosphorylation → down-regulates activity | GPRC5A | SIGNOR-278335 |
| EGFR | phosphorylation → up-regulates activity | IKBKE | SIGNOR-277242 |
| EGFR | phosphorylation → down-regulates activity | BECN1 | SIGNOR-278357 |
| EGFR | phosphorylation → up-regulates activity | PELI1 | SIGNOR-277873 |
| EGFR | phosphorylation → up-regulates quantity by stabilization | SOX2 | SIGNOR-279036 |
| EGFR | phosphorylation → up-regulates activity | SHC3 | SIGNOR-273922 |
| EGFR | phosphorylation → up-regulates | PLCG1 | SIGNOR-20976 |
| EGFR | phosphorylation → up-regulates activity | EGFR | SIGNOR-235956 |
| EGFR | phosphorylation → up-regulates activity | EGFR | SIGNOR-236475 |
| EGFR | phosphorylation → up-regulates | EPS15 | SIGNOR-203311 |
| EGFR | phosphorylation → up-regulates activity | MUC1 | SIGNOR-109538 |
| EGFR | phosphorylation → up-regulates | GSTP1 | SIGNOR-184387 |
| EGFR | phosphorylation → up-regulates activity | EGFR | SIGNOR-236516 |
| EGFR | phosphorylation → up-regulates | GSTP1 | SIGNOR-184379 |
| EGFR | phosphorylation → up-regulates activity | PLD2 | SIGNOR-251095 |
| EGFR | phosphorylation → up-regulates activity | IKBKE | SIGNOR-277243 |
| EGFR | phosphorylation → up-regulates | PKIA | SIGNOR-22455 |
| EGFR | phosphorylation → up-regulates activity | IKBKE | SIGNOR-278222 |
| EGFR | phosphorylation → down-regulates activity | CCDC50 | SIGNOR-262850 |
| EGFR | phosphorylation → up-regulates activity | HGS | SIGNOR-100246 |
| EGFR | phosphorylation down-regulates | CALM1 | SIGNOR-34691 |
| EGFR | phosphorylation → unknown | CTNND1 | SIGNOR-251092 |
| EGFR | phosphorylation → up-regulates | ERBB3 | SIGNOR-34748 |
| EGFR | phosphorylation → up-regulates activity | EGFR | SIGNOR-251093 |
| EGFR | phosphorylation → down-regulates activity | LRRK1 | SIGNOR-262856 |
| EGFR | phosphorylation → up-regulates activity | GNAI1 | SIGNOR-277226 |
| EGFR | phosphorylation → down-regulates activity | SQSTM1 | SIGNOR-277500 |
| EGFR | phosphorylation down-regulates | HDAC6 | SIGNOR-162431 |
| EGFR | phosphorylation → up-regulates activity | GAB1 | SIGNOR-233233 |
| EGFR | phosphorylation → up-regulates activity | GNAI1 | SIGNOR-277227 |
| EGFR | phosphorylation → up-regulates activity | ATM | SIGNOR-276872 |
| EGFR | phosphorylation → up-regulates activity | SCAMP3 | SIGNOR-262858 |
| EGFR | phosphorylation → up-regulates activity | NIBAN2 | SIGNOR-273637 |
| EGFR | phosphorylation down-regulates | EPB41 | SIGNOR-20452 |
| EGFR | phosphorylation → up-regulates | EZR | SIGNOR-133215 |
| EGFR | phosphorylation → up-regulates activity | GAB1 | SIGNOR-236412 |
| EGFR | phosphorylation → up-regulates | VAV2 | SIGNOR-95976 |
| EGFR | phosphorylation → up-regulates | GAB1 | SIGNOR-236396 |
| EGFR | phosphorylation → unknown | SCAMP3 | SIGNOR-251096 |
| EGFR | phosphorylation → up-regulates | GAB1 | SIGNOR-236404 |
| EGFR | phosphorylation → up-regulates activity | GNAI1 | SIGNOR-277228 |
| EGFR | phosphorylation → down-regulates activity | CCDC50 | SIGNOR-262852 |
| EGFR | phosphorylation → up-regulates activity | KCND3 | SIGNOR-275549 |
| EGFR | phosphorylation → up-regulates activity | KCNN1 | SIGNOR-276490 |
| EGFR | phosphorylation → up-regulates activity | JAK1/STAT1/STAT3 | SIGNOR-252088 |
| EGFR | phosphorylation → up-regulates activity | EGFR | SIGNOR-236483 |
| EGFR | phosphorylation → up-regulates activity | STAT3 | SIGNOR-235692 |
| EGFR | phosphorylation → up-regulates | GAB1 | SIGNOR-236420 |
| EGFR | phosphorylation → up-regulates | PTPN1 | SIGNOR-52950 |
| EGFR | phosphorylation → up-regulates | STAT5B | SIGNOR-113401 |
| EGFR | phosphorylation → up-regulates activity | KCND3 | SIGNOR-276397 |