Entity Details

Name EGFR_Tyr1092
ID P00533
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PTPRJEGFRTyr1092 TFLPVPEyINQSVPKdephosphorylation
up-regulates quantity by stabilization
19836242SIGNOR-248698
EGFREGFRTyr1092 TFLPVPEyINQSVPKphosphorylation
up-regulates activity
10653583SIGNOR-236479
PTPRKEGFRTyr1092 TFLPVPEyINQSVPKdephosphorylation
unknown
16263724SIGNOR-248722
EGFREGFRTyr1092 TFLPVPEyINQSVPKphosphorylation
up-regulates activity
16122376SIGNOR-236523
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PTPRJdephosphorylation
down-regulates
EGFR
PTyr1092
dephosphorylation
down-regulates
EGFR19836242SIGNOR-248698
EGFRphosphorylation
up-regulates
EGFR
PTyr1092
phosphorylation
up-regulates
EGFR10653583SIGNOR-236479
PTPRKdephosphorylation
down-regulates
EGFR
PTyr1092
dephosphorylation
up-regulates
EGFR16263724SIGNOR-248722
EGFRphosphorylation
up-regulates
EGFR
PTyr1092
phosphorylation
up-regulates
EGFR16122376SIGNOR-236523
Regulator Mechanism/Effect Target SIGNOR-ID
PTPRJdephosphorylation

up-regulates quantity by stabilization
EGFRSIGNOR-248698
EGFRphosphorylation

up-regulates activity
EGFRSIGNOR-236479
PTPRKdephosphorylation

unknown
EGFRSIGNOR-248722
EGFRphosphorylation

up-regulates activity
EGFRSIGNOR-236523