Entity Details

Name EGFR_Tyr869
ID P00533
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
EGFREGFRTyr869LGAEEKEyHAEGGKVphosphorylation
up-regulates activity		16122376SIGNOR-235956
EGFREGFRTyr869LGAEEKEyHAEGGKVphosphorylation
up-regulates activity		10653583SIGNOR-236487
SRCEGFRTyr869LGAEEKEyHAEGGKVphosphorylation
up-regulates activity		11983694SIGNOR-235921
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
EGFRphosphorylation
up-regulates
→
EGFR
PTyr869		phosphorylation
up-regulates
→		EGFR16122376SIGNOR-235956
EGFRphosphorylation
up-regulates
→
EGFR
PTyr869		phosphorylation
up-regulates
→		EGFR10653583SIGNOR-236487
SRCphosphorylation
up-regulates
→
EGFR
PTyr869		phosphorylation
up-regulates
→		EGFR11983694SIGNOR-235921
Regulator Mechanism/Effect Target SIGNOR-ID
EGFRphosphorylation
→
up-regulates activity 		EGFRSIGNOR-235956
EGFRphosphorylation
→
up-regulates activity 		EGFRSIGNOR-236487
SRCphosphorylation
→
up-regulates activity 		EGFRSIGNOR-235921