| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK1A1 | MYC | Ser267 | PPTTSSDsEEEQEDE | phosphorylation down-regulates quantity by destabilization | 22025562 | SIGNOR-276387 |
| CSNK2A1 | MYC | Ser267 | PPTTSSDsEEEQEDE | phosphorylation down-regulates quantity by destabilization | 22025562 | SIGNOR-276388 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK1A1 | phosphorylation up-regulates → | MYC PSer267 | phosphorylation down-regulates ⊣ | MYC | 22025562 | SIGNOR-276387 |
| CSNK2A1 | phosphorylation up-regulates → | MYC PSer267 | phosphorylation down-regulates ⊣ | MYC | 22025562 | SIGNOR-276388 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CSNK1A1 | phosphorylation![]() down-regulates quantity by destabilization | MYC | SIGNOR-276387 |
| CSNK2A1 | phosphorylation![]() down-regulates quantity by destabilization | MYC | SIGNOR-276388 |