Entity Details

Name HRAS
ID P01112
Role kinase
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
HRASJUNSer63KNSDLLTsPDVGLLKphosphorylation
up-regulates activity		12169099SIGNOR-235522
HRASJUNSer73VGLLKLAsPELERLIphosphorylation
up-regulates activity		12169099SIGNOR-235526
HRASJUNSer63KNSDLLTsPDVGLLKphosphorylation
up-regulates activity		1749429SIGNOR-236682
HRASJUNSer73VGLLKLAsPELERLIphosphorylation
up-regulates activity		1749429SIGNOR-236686
HRASGATA2Ser192PSTTGAAsPASSSAGphosphorylation
up-regulates activity		25056917SIGNOR-259945
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
HRASphosphorylation
up-regulates
→
JUN
PSer63		phosphorylation
up-regulates
→		JUN12169099SIGNOR-235522
HRASphosphorylation
up-regulates
→
JUN
PSer73		phosphorylation
up-regulates
→		JUN12169099SIGNOR-235526
HRASphosphorylation
up-regulates
→
JUN
PSer63		phosphorylation
up-regulates
→		JUN1749429SIGNOR-236682
HRASphosphorylation
up-regulates
→
JUN
PSer73		phosphorylation
up-regulates
→		JUN1749429SIGNOR-236686
HRASphosphorylation
up-regulates
→
GATA2
PSer192		phosphorylation
up-regulates
→		GATA225056917SIGNOR-259945
Regulator Mechanism/Effect Target SIGNOR-ID
HRASphosphorylation
→
up-regulates activity 		JUNSIGNOR-235522
HRASphosphorylation
→
up-regulates activity 		JUNSIGNOR-235526
HRASphosphorylation
→
up-regulates activity 		JUNSIGNOR-236682
HRASphosphorylation
→
up-regulates activity 		JUNSIGNOR-236686
HRASphosphorylation
→
up-regulates activity 		GATA2SIGNOR-259945