Entity Details

Name HRAS
ID P01112
Role substrate
Enzymatic Domains
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
SRCHRASTyr32QNHFVDEyDPTIEDSphosphorylation
down-regulates activity		25157176SIGNOR-252093
PTPN11HRASTyr32QNHFVDEyDPTIEDSdephosphorylation
up-regulates activity		26617336SIGNOR-252094
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
SRCphosphorylation
up-regulates
→
HRAS
PTyr32		phosphorylation
down-regulates
⊣		HRAS25157176SIGNOR-252093
PTPN11dephosphorylation
down-regulates
⊣
HRAS
PTyr32		dephosphorylation
down-regulates
⊣		HRAS26617336SIGNOR-252094
Regulator Mechanism/Effect Target SIGNOR-ID
SRCphosphorylation
→
down-regulates activity 		HRASSIGNOR-252093
PTPN11dephosphorylation
→
up-regulates activity 		HRASSIGNOR-252094