| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACA | ESR1 | Ser236 | IDKNRRKsCQACRLR | phosphorylation down-regulates | 9891036 | SIGNOR-63984 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACA | phosphorylation up-regulates → | ESR1 PSer236 | phosphorylation down-regulates ⊣ | ESR1 | 9891036 | SIGNOR-63984 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKACA | phosphorylation down-regulates | ESR1 | SIGNOR-63984 |
