| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK2 | TK1 | Ser13 | LPTVLPGsPSKTRGQ | phosphorylation down-regulates | 14697231 | SIGNOR-120372 |
| CDK1 | TK1 | Ser13 | LPTVLPGsPSKTRGQ | phosphorylation down-regulates | 12435275 | SIGNOR-95574 |
| CDK2 | TK1 | Ser13 | LPTVLPGsPSKTRGQ | phosphorylation down-regulates | 12435275 | SIGNOR-95578 |
| CDK1 | TK1 | Ser13 | LPTVLPGsPSKTRGQ | phosphorylation down-regulates | 14697231 | SIGNOR-120368 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK2 | phosphorylation up-regulates → | TK1 PSer13 | phosphorylation down-regulates ⊣ | TK1 | 14697231 | SIGNOR-120372 |
| CDK1 | phosphorylation up-regulates → | TK1 PSer13 | phosphorylation down-regulates ⊣ | TK1 | 12435275 | SIGNOR-95574 |
| CDK2 | phosphorylation up-regulates → | TK1 PSer13 | phosphorylation down-regulates ⊣ | TK1 | 12435275 | SIGNOR-95578 |
| CDK1 | phosphorylation up-regulates → | TK1 PSer13 | phosphorylation down-regulates ⊣ | TK1 | 14697231 | SIGNOR-120368 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK2 | phosphorylation down-regulates | TK1 | SIGNOR-120372 |
| CDK1 | phosphorylation down-regulates | TK1 | SIGNOR-95574 |
| CDK2 | phosphorylation down-regulates | TK1 | SIGNOR-95578 |
| CDK1 | phosphorylation down-regulates | TK1 | SIGNOR-120368 |
