Entity Details

Name ERBB2_Tyr1023
ID P04626
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PTPN11ERBB2Tyr1023DLVDAEEyLVPQQGFdephosphorylation
down-regulates		32024694SIGNOR-262957
ERBB2ERBB2Tyr1023DLVDAEEyLVPQQGFphosphorylation
up-regulates activity		1706616SIGNOR-251129
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PTPN11dephosphorylation
down-regulates
⊣
ERBB2
PTyr1023		dephosphorylation
up-regulates
→		ERBB232024694SIGNOR-262957
ERBB2phosphorylation
up-regulates
→
ERBB2
PTyr1023		phosphorylation
up-regulates
→		ERBB21706616SIGNOR-251129
Regulator Mechanism/Effect Target SIGNOR-ID
PTPN11dephosphorylation
img/direct_inhibition.png
down-regulates 		ERBB2SIGNOR-262957
ERBB2phosphorylation
→
up-regulates activity 		ERBB2SIGNOR-251129