| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| DUSP3 | ERBB2 | Tyr877 | LDIDETEyHADGGKV | dephosphorylation down-regulates activity | 21262974 | SIGNOR-248533 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| DUSP3 | dephosphorylation down-regulates ⊣ | ERBB2 PTyr877 | dephosphorylation up-regulates → | ERBB2 | 21262974 | SIGNOR-248533 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| DUSP3 | dephosphorylation → down-regulates activity | ERBB2 | SIGNOR-248533 |
