Entity Details

Name PTPN18_Tyr1112
ID P04626
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PTPN18ERBB2Tyr1112DPSPLQRySEDPTVPdephosphorylation
down-regulates quantity by destabilization		25081058SIGNOR-262595
ERBB2ERBB2Tyr1112DPSPLQRySEDPTVPphosphorylation
down-regulates		1706616SIGNOR-21211
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PTPN18dephosphorylation
down-regulates
⊣
ERBB2
PTyr1112		dephosphorylation
up-regulates
→		ERBB225081058SIGNOR-262595
ERBB2phosphorylation
up-regulates
→
ERBB2
PTyr1112		phosphorylation
down-regulates
⊣		ERBB21706616SIGNOR-21211
Regulator Mechanism/Effect Target SIGNOR-ID
PTPN18dephosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		ERBB2SIGNOR-262595
ERBB2phosphorylation
img/direct_inhibition.png
down-regulates 		ERBB2SIGNOR-21211