Entity Details

Name MAPK1_Ser16
ID P05023
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK1ATP1A1Ser16KYEPAAVsEQGDKKGphosphorylation
down-regulates activity		14976217SIGNOR-262940
PRKCZATP1A1Ser16KYEPAAVsEQGDKKGphosphorylation
up-regulates activity		12671055SIGNOR-263181
PRKCAATP1A1Ser16KYEPAAVsEQGDKKGphosphorylation
down-regulates activity		14976217SIGNOR-262941
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK1phosphorylation
up-regulates
→
ATP1A1
PSer16		phosphorylation
down-regulates
⊣		ATP1A114976217SIGNOR-262940
PRKCZphosphorylation
up-regulates
→
ATP1A1
PSer16		phosphorylation
up-regulates
→		ATP1A112671055SIGNOR-263181
PRKCAphosphorylation
up-regulates
→
ATP1A1
PSer16		phosphorylation
down-regulates
⊣		ATP1A114976217SIGNOR-262941
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK1phosphorylation
→
down-regulates activity 		ATP1A1SIGNOR-262940
PRKCZphosphorylation
→
up-regulates activity 		ATP1A1SIGNOR-263181
PRKCAphosphorylation
→
down-regulates activity 		ATP1A1SIGNOR-262941