Entity Details

Name ALDH2
ID P05091
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKCEALDH2Thr202KLGPALAtGNVVVMKphosphorylation
up-regulates activity		28056995SIGNOR-271865
PRKAA1ALDH2Thr356GNPFDSKtEQGPQVDphosphorylation
up-regulates activity		30375985SIGNOR-271863
PRKCEALDH2Ser296KSPNIIMsDADMDWAphosphorylation
up-regulates activity		28056995SIGNOR-271864
PRKCEALDH2Thr429MQILKFKtIEEVVGRphosphorylation
up-regulates activity		28056995SIGNOR-271866
AMPKALDH2Thr356GNPFDSKtEQGPQVDphosphorylation
up-regulates activity		30375985SIGNOR-271862
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PRKCEphosphorylation
up-regulates
→
ALDH2
PThr202		phosphorylation
up-regulates
→		ALDH228056995SIGNOR-271865
PRKAA1phosphorylation
up-regulates
→
ALDH2
PThr356		phosphorylation
up-regulates
→		ALDH230375985SIGNOR-271863
PRKCEphosphorylation
up-regulates
→
ALDH2
PSer296		phosphorylation
up-regulates
→		ALDH228056995SIGNOR-271864
PRKCEphosphorylation
up-regulates
→
ALDH2
PThr429		phosphorylation
up-regulates
→		ALDH228056995SIGNOR-271866
AMPKphosphorylation
up-regulates
→
ALDH2
PThr356		phosphorylation
up-regulates
→		ALDH230375985SIGNOR-271862
Regulator Mechanism/Effect Target SIGNOR-ID
PRKCEphosphorylation
→
up-regulates activity 		ALDH2SIGNOR-271865
PRKAA1phosphorylation
→
up-regulates activity 		ALDH2SIGNOR-271863
PRKCEphosphorylation
→
up-regulates activity 		ALDH2SIGNOR-271864
PRKCEphosphorylation
→
up-regulates activity 		ALDH2SIGNOR-271866
AMPKphosphorylation
→
up-regulates activity 		ALDH2SIGNOR-271862