Entity Details

Name PDK1_Thr779
ID P05106
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKT1ITGB3Thr779LYKEATStFTNITYRphosphorylation
down-regulates activity		10896934SIGNOR-252552
AKTITGB3Thr779LYKEATStFTNITYRphosphorylation
down-regulates activity		10896934SIGNOR-251479
PDK1ITGB3Thr779LYKEATStFTNITYRphosphorylation
down-regulates activity		10896934SIGNOR-250264
PDPK1ITGB3Thr779LYKEATStFTNITYRphosphorylation
down-regulates activity		10896934SIGNOR-250266
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKT1phosphorylation
up-regulates
→
ITGB3
PThr779		phosphorylation
down-regulates
⊣		ITGB310896934SIGNOR-252552
AKTphosphorylation
up-regulates
→
ITGB3
PThr779		phosphorylation
down-regulates
⊣		ITGB310896934SIGNOR-251479
PDK1phosphorylation
up-regulates
→
ITGB3
PThr779		phosphorylation
down-regulates
⊣		ITGB310896934SIGNOR-250264
PDPK1phosphorylation
up-regulates
→
ITGB3
PThr779		phosphorylation
down-regulates
⊣		ITGB310896934SIGNOR-250266
Regulator Mechanism/Effect Target SIGNOR-ID
AKT1phosphorylation
→
down-regulates activity 		ITGB3SIGNOR-252552
AKTphosphorylation
→
down-regulates activity 		ITGB3SIGNOR-251479
PDK1phosphorylation
→
down-regulates activity 		ITGB3SIGNOR-250264
PDPK1phosphorylation
→
down-regulates activity 		ITGB3SIGNOR-250266