| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | HMGN2 | Ser29 | QRRSARLsAKPAPPK | phosphorylation down-regulates | 10739259 | SIGNOR-76324 |
| RPS6KA3 | HMGN2 | Ser29 | QRRSARLsAKPAPPK | phosphorylation down-regulates activity | 11438671 | SIGNOR-249103 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | phosphorylation up-regulates → | HMGN2 PSer29 | phosphorylation down-regulates ⊣ | HMGN2 | 10739259 | SIGNOR-76324 |
| RPS6KA3 | phosphorylation up-regulates → | HMGN2 PSer29 | phosphorylation down-regulates ⊣ | HMGN2 | 11438671 | SIGNOR-249103 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCA | phosphorylation down-regulates | HMGN2 | SIGNOR-76324 |
| RPS6KA3 | phosphorylation → down-regulates activity | HMGN2 | SIGNOR-249103 |
