| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACA | TFAP2A | Ser239 | AEVQRRLsPPECLNA | phosphorylation up-regulates | 10037142 | SIGNOR-64955 |
| PRKAA2 | TFAP2A | Ser219 | CSVPGRLsLLSSTSK | phosphorylation up-regulates activity | 22561688 | SIGNOR-279648 |
| CSNK2A1 | TFAP2A | Ser429 | TDNNAKSsDKEEKHR | phosphorylation up-regulates | 21777522 | SIGNOR-175130 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACA | phosphorylation up-regulates → | TFAP2A PSer239 | phosphorylation up-regulates → | TFAP2A | 10037142 | SIGNOR-64955 |
| PRKAA2 | phosphorylation up-regulates → | TFAP2A PSer219 | phosphorylation up-regulates → | TFAP2A | 22561688 | SIGNOR-279648 |
| CSNK2A1 | phosphorylation up-regulates → | TFAP2A PSer429 | phosphorylation up-regulates → | TFAP2A | 21777522 | SIGNOR-175130 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKACA | phosphorylation → up-regulates | TFAP2A | SIGNOR-64955 |
| PRKAA2 | phosphorylation → up-regulates activity | TFAP2A | SIGNOR-279648 |
| CSNK2A1 | phosphorylation → up-regulates | TFAP2A | SIGNOR-175130 |
