| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTP4A3 | ITGB1 | Tyr783 | DTGENPIyKSAVTTV | dephosphorylation down-regulates activity | 23092334 | SIGNOR-277050 |
| PTPRG | ITGB1 | Tyr783 | DTGENPIyKSAVTTV | dephosphorylation down-regulates activity | 25624455 | SIGNOR-254706 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTP4A3 | dephosphorylation down-regulates ⊣ | ITGB1 PTyr783 | dephosphorylation up-regulates → | ITGB1 | 23092334 | SIGNOR-277050 |
| PTPRG | dephosphorylation down-regulates ⊣ | ITGB1 PTyr783 | dephosphorylation up-regulates → | ITGB1 | 25624455 | SIGNOR-254706 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PTP4A3 | dephosphorylation → down-regulates activity | ITGB1 | SIGNOR-277050 |
| PTPRG | dephosphorylation → down-regulates activity | ITGB1 | SIGNOR-254706 |