Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
BLVRA	PRKCB	Thr500 View in OncoXplorer	WDGVTTKtFCGTPDY	phosphorylation up-regulates	17227757	SIGNOR-152181
PHLPP2	PRKCB	Ser661	QNEFAGFsYTNPEFV	dephosphorylation down-regulates quantity by destabilization	18162466	SIGNOR-248727
PRKCB	PRKCB	Thr17	PSEGEEStVRFARKG	phosphorylation unknown	2377895	SIGNOR-248868
PPP2CA	PRKCB	Thr500 View in OncoXplorer	WDGVTTKtFCGTPDY	dephosphorylation down-regulates activity	8749392	SIGNOR-248620
PRKCB	PRKCB	Ser661	QNEFAGFsYTNPEFV	phosphorylation up-regulates activity	17115692	SIGNOR-150861
PDPK1	PRKCB	–		phosphorylation up-regulates	15209375	SIGNOR-126069
PDPK1	PRKCB	Thr500 View in OncoXplorer	WDGVTTKtFCGTPDY	phosphorylation up-regulates	17115692	SIGNOR-150857
PRKCB	PRKCB	Ser16	PPSEGEEsTVRFARK	phosphorylation unknown	2377895	SIGNOR-248863
PPP2CB	PRKCB	Thr500 View in OncoXplorer	WDGVTTKtFCGTPDY	dephosphorylation down-regulates activity	8749392	SIGNOR-248585
PRKCB	PRKCB	Thr642 View in OncoXplorer	TRQPVELtPTDKLFI	phosphorylation up-regulates	17115692	SIGNOR-150865
PRKCB	PRKCB	Ser661	QNEFAGFsYTNPEFV	phosphorylation up-regulates activity	10828076	SIGNOR-77583
PHLPP1	PRKCB	Ser661	QNEFAGFsYTNPEFV	dephosphorylation down-regulates quantity by destabilization	18162466	SIGNOR-248326
PHLPP1	PRKCB	Ser661	QNEFAGFsYTNPEFV	dephosphorylation down-regulates quantity	18162466	SIGNOR-237047
PHLPP2	PRKCB	Ser661	QNEFAGFsYTNPEFV	dephosphorylation down-regulates quantity	18162466	SIGNOR-237039

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
BLVRA	phosphorylation up-regulates →	PRKCB PThr500	phosphorylation up-regulates →	PRKCB	17227757	SIGNOR-152181
PHLPP2	dephosphorylation down-regulates ⊣	PRKCB PSer661	dephosphorylation up-regulates →	PRKCB	18162466	SIGNOR-248727
PRKCB	phosphorylation up-regulates →	PRKCB PThr17	phosphorylation down-regulates ⊣	PRKCB	2377895	SIGNOR-248868
PPP2CA	dephosphorylation down-regulates ⊣	PRKCB PThr500	dephosphorylation up-regulates →	PRKCB	8749392	SIGNOR-248620
PRKCB	phosphorylation up-regulates →	PRKCB PSer661	phosphorylation up-regulates →	PRKCB	17115692	SIGNOR-150861
PDPK1	phosphorylation up-regulates →	PRKCB PThr500	phosphorylation up-regulates →	PRKCB	17115692	SIGNOR-150857
PRKCB	phosphorylation up-regulates →	PRKCB PSer16	phosphorylation down-regulates ⊣	PRKCB	2377895	SIGNOR-248863
PPP2CB	dephosphorylation down-regulates ⊣	PRKCB PThr500	dephosphorylation up-regulates →	PRKCB	8749392	SIGNOR-248585
PRKCB	phosphorylation up-regulates →	PRKCB PThr642	phosphorylation up-regulates →	PRKCB	17115692	SIGNOR-150865
PRKCB	phosphorylation up-regulates →	PRKCB PSer661	phosphorylation up-regulates →	PRKCB	10828076	SIGNOR-77583
PHLPP1	dephosphorylation down-regulates ⊣	PRKCB PSer661	dephosphorylation up-regulates →	PRKCB	18162466	SIGNOR-248326
PHLPP1	dephosphorylation down-regulates ⊣	PRKCB PSer661	dephosphorylation up-regulates →	PRKCB	18162466	SIGNOR-237047
PHLPP2	dephosphorylation down-regulates ⊣	PRKCB PSer661	dephosphorylation up-regulates →	PRKCB	18162466	SIGNOR-237039

Regulator	Mechanism/Effect	Target	SIGNOR-ID
BLVRA	phosphorylation → up-regulates	PRKCB	SIGNOR-152181
PHLPP2	dephosphorylation down-regulates quantity by destabilization	PRKCB	SIGNOR-248727
PRKCB	phosphorylation → unknown	PRKCB	SIGNOR-248868
PPP2CA	dephosphorylation → down-regulates activity	PRKCB	SIGNOR-248620
PRKCB	phosphorylation → up-regulates activity	PRKCB	SIGNOR-150861
PDPK1	phosphorylation → up-regulates	PRKCB	SIGNOR-126069
PDPK1	phosphorylation → up-regulates	PRKCB	SIGNOR-150857
PRKCB	phosphorylation → unknown	PRKCB	SIGNOR-248863
PPP2CB	dephosphorylation → down-regulates activity	PRKCB	SIGNOR-248585
PRKCB	phosphorylation → up-regulates	PRKCB	SIGNOR-150865
PRKCB	phosphorylation → up-regulates activity	PRKCB	SIGNOR-77583
PHLPP1	dephosphorylation down-regulates quantity by destabilization	PRKCB	SIGNOR-248326
PHLPP1	dephosphorylation → down-regulates quantity	PRKCB	SIGNOR-237047
PHLPP2	dephosphorylation → down-regulates quantity	PRKCB	SIGNOR-237039