Entity Details

Name	PRKCB
ID	P05771-2
Role	substrate
Enzymatic Domains
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Data Summary

PTM Format

SIGNOR Summary

Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
PPP2CA	PRKCB	Ser660 View in OncoXplorer	QSEFEGFsFVNSEFL	dephosphorylation down-regulates activity	15880462	SIGNOR-248621
PPP2CB	PRKCB	Ser660 View in OncoXplorer	QSEFEGFsFVNSEFL	dephosphorylation down-regulates activity	15880462	SIGNOR-248586
PPP2CA	PRKCB	Thr641 View in OncoXplorer	TRHPPVLtPPDQEVI	dephosphorylation down-regulates activity	8749392	SIGNOR-248622
PPP2CB	PRKCB	Thr641 View in OncoXplorer	TRHPPVLtPPDQEVI	dephosphorylation down-regulates activity	8749392	SIGNOR-248587

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
PPP2CA	dephosphorylation down-regulates ⊣	PRKCB PSer660	dephosphorylation up-regulates →	PRKCB	15880462	SIGNOR-248621
PPP2CB	dephosphorylation down-regulates ⊣	PRKCB PSer660	dephosphorylation up-regulates →	PRKCB	15880462	SIGNOR-248586
PPP2CA	dephosphorylation down-regulates ⊣	PRKCB PThr641	dephosphorylation up-regulates →	PRKCB	8749392	SIGNOR-248622
PPP2CB	dephosphorylation down-regulates ⊣	PRKCB PThr641	dephosphorylation up-regulates →	PRKCB	8749392	SIGNOR-248587

Regulator	Mechanism/Effect	Target	SIGNOR-ID
PPP2CA	dephosphorylation → down-regulates activity	PRKCB	SIGNOR-248621
PPP2CB	dephosphorylation → down-regulates activity	PRKCB	SIGNOR-248586
PPP2CA	dephosphorylation → down-regulates activity	PRKCB	SIGNOR-248622
PPP2CB	dephosphorylation → down-regulates activity	PRKCB	SIGNOR-248587