| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP2CA | PRKCB | Thr641 | TRHPPVLtPPDQEVI | dephosphorylation down-regulates activity | 8749392 | SIGNOR-248622 |
| PPP2CB | PRKCB | Thr641 | TRHPPVLtPPDQEVI | dephosphorylation down-regulates activity | 8749392 | SIGNOR-248587 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP2CA | dephosphorylation down-regulates ⊣ | PRKCB PThr641 | dephosphorylation up-regulates → | PRKCB | 8749392 | SIGNOR-248622 |
| PPP2CB | dephosphorylation down-regulates ⊣ | PRKCB PThr641 | dephosphorylation up-regulates → | PRKCB | 8749392 | SIGNOR-248587 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PPP2CA | dephosphorylation → down-regulates activity | PRKCB | SIGNOR-248622 |
| PPP2CB | dephosphorylation → down-regulates activity | PRKCB | SIGNOR-248587 |