| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP2CA | PRKCB | Thr500 | WDGVTTKtFCGTPDY | dephosphorylation down-regulates activity | 8749392 | SIGNOR-248620 |
| PDPK1 | PRKCB | Thr500 | WDGVTTKtFCGTPDY | phosphorylation up-regulates | 17115692 | SIGNOR-150857 |
| PPP2CB | PRKCB | Thr500 | WDGVTTKtFCGTPDY | dephosphorylation down-regulates activity | 8749392 | SIGNOR-248585 |
| BLVRA | PRKCB | Thr500 | WDGVTTKtFCGTPDY | phosphorylation up-regulates | 17227757 | SIGNOR-152181 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP2CA | dephosphorylation down-regulates ⊣ | PRKCB PThr500 | dephosphorylation up-regulates → | PRKCB | 8749392 | SIGNOR-248620 |
| PDPK1 | phosphorylation up-regulates → | PRKCB PThr500 | phosphorylation up-regulates → | PRKCB | 17115692 | SIGNOR-150857 |
| PPP2CB | dephosphorylation down-regulates ⊣ | PRKCB PThr500 | dephosphorylation up-regulates → | PRKCB | 8749392 | SIGNOR-248585 |
| BLVRA | phosphorylation up-regulates → | PRKCB PThr500 | phosphorylation up-regulates → | PRKCB | 17227757 | SIGNOR-152181 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PPP2CA | dephosphorylation → down-regulates activity | PRKCB | SIGNOR-248620 |
| PDPK1 | phosphorylation → up-regulates | PRKCB | SIGNOR-150857 |
| PPP2CB | dephosphorylation → down-regulates activity | PRKCB | SIGNOR-248585 |
| BLVRA | phosphorylation → up-regulates | PRKCB | SIGNOR-152181 |
