| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN1 | KRT8 | Tyr267 | IAEVKAQyEDIANRS | dephosphorylation down-regulates activity | 24003221 | SIGNOR-265495 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN1 | dephosphorylation down-regulates ⊣ | KRT8 PTyr267 | dephosphorylation up-regulates → | KRT8 | 24003221 | SIGNOR-265495 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PTPN1 | dephosphorylation → down-regulates activity | KRT8 | SIGNOR-265495 |
