Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
SRC	ENO1	Tyr44 View in OncoXplorer	SGASTGIyEALELRD	phosphorylation up-regulates	24841372	SIGNOR-205092
ULK1	ENO1	Ser282	QLADLYKsFIKDYPV	phosphorylation down-regulates activity	27153534	SIGNOR-274029
SRC	ENO1	Tyr44 View in OncoXplorer	SGASTGIyEALELRD	phosphorylation up-regulates	7629021	SIGNOR-30126
ULK2	ENO1	Ser115	ANAILGVsLAVCKAG	phosphorylation down-regulates activity	27153534	SIGNOR-274038
ULK2	ENO1	Ser282	QLADLYKsFIKDYPV	phosphorylation down-regulates activity	27153534	SIGNOR-274037
ULK1	ENO1	Ser115	ANAILGVsLAVCKAG	phosphorylation down-regulates activity	27153534	SIGNOR-274030

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
SRC	phosphorylation up-regulates →	ENO1 PTyr44	phosphorylation up-regulates →	ENO1	24841372	SIGNOR-205092
ULK1	phosphorylation up-regulates →	ENO1 PSer282	phosphorylation down-regulates ⊣	ENO1	27153534	SIGNOR-274029
SRC	phosphorylation up-regulates →	ENO1 PTyr44	phosphorylation up-regulates →	ENO1	7629021	SIGNOR-30126
ULK2	phosphorylation up-regulates →	ENO1 PSer115	phosphorylation down-regulates ⊣	ENO1	27153534	SIGNOR-274038
ULK2	phosphorylation up-regulates →	ENO1 PSer282	phosphorylation down-regulates ⊣	ENO1	27153534	SIGNOR-274037
ULK1	phosphorylation up-regulates →	ENO1 PSer115	phosphorylation down-regulates ⊣	ENO1	27153534	SIGNOR-274030

Regulator	Mechanism/Effect	Target	SIGNOR-ID
SRC	phosphorylation → up-regulates	ENO1	SIGNOR-205092
ULK1	phosphorylation → down-regulates activity	ENO1	SIGNOR-274029
SRC	phosphorylation → up-regulates	ENO1	SIGNOR-30126
ULK2	phosphorylation → down-regulates activity	ENO1	SIGNOR-274038
ULK2	phosphorylation → down-regulates activity	ENO1	SIGNOR-274037
ULK1	phosphorylation → down-regulates activity	ENO1	SIGNOR-274030