| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ULK1 | ENO1 | Ser115 | ANAILGVsLAVCKAG | phosphorylation down-regulates activity | 27153534 | SIGNOR-274030 |
| ULK2 | ENO1 | Ser115 | ANAILGVsLAVCKAG | phosphorylation down-regulates activity | 27153534 | SIGNOR-274038 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ULK1 | phosphorylation up-regulates → | ENO1 PSer115 | phosphorylation down-regulates ⊣ | ENO1 | 27153534 | SIGNOR-274030 |
| ULK2 | phosphorylation up-regulates → | ENO1 PSer115 | phosphorylation down-regulates ⊣ | ENO1 | 27153534 | SIGNOR-274038 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ULK1 | phosphorylation → down-regulates activity | ENO1 | SIGNOR-274030 |
| ULK2 | phosphorylation → down-regulates activity | ENO1 | SIGNOR-274038 |