| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CHUK | NPM1 | Ser125 | AVEEDAEsEDEEEED | phosphorylation up-regulates activity | 24290756 | SIGNOR-279405 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CHUK | phosphorylation up-regulates → | NPM1 PSer125 | phosphorylation up-regulates → | NPM1 | 24290756 | SIGNOR-279405 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CHUK | phosphorylation → up-regulates activity | NPM1 | SIGNOR-279405 |
