| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPKAPK2 | TH | Ser19 | KGFRRAVsELDAKQA | phosphorylation up-regulates activity | 11359875 | SIGNOR-250149 |
| CAMK2A | TH | Ser19 | KGFRRAVsELDAKQA | phosphorylation up-regulates | 1680128 | SIGNOR-20912 |
| CAMK2G | TH | Ser19 | KGFRRAVsELDAKQA | phosphorylation up-regulates activity | 1680128 | SIGNOR-250709 |
| MAPKAPK5 | TH | Ser19 | KGFRRAVsELDAKQA | phosphorylation up-regulates | 12421349 | SIGNOR-95479 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPKAPK2 | phosphorylation up-regulates → | TH PSer19 | phosphorylation up-regulates → | TH | 11359875 | SIGNOR-250149 |
| CAMK2A | phosphorylation up-regulates → | TH PSer19 | phosphorylation up-regulates → | TH | 1680128 | SIGNOR-20912 |
| CAMK2G | phosphorylation up-regulates → | TH PSer19 | phosphorylation up-regulates → | TH | 1680128 | SIGNOR-250709 |
| MAPKAPK5 | phosphorylation up-regulates → | TH PSer19 | phosphorylation up-regulates → | TH | 12421349 | SIGNOR-95479 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPKAPK2 | phosphorylation → up-regulates activity | TH | SIGNOR-250149 |
| CAMK2A | phosphorylation → up-regulates | TH | SIGNOR-20912 |
| CAMK2G | phosphorylation → up-regulates activity | TH | SIGNOR-250709 |
| MAPKAPK5 | phosphorylation → up-regulates | TH | SIGNOR-95479 |
