| Name | CSF1R |
| ID | P07333 |
| Role | kinase |
| Enzymatic Domains |
Ig-like C2-type 1 21-104
Ig-like C2-type 2 107-197
Ig-like C2-type 3 203-290
Ig-like C2-type 4 299-399
Ig-like C2-type 5 402-502
Protein kinase 582-910 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSF1R | CTNND1 | Tyr228 | YPGGSDNyGSLSRVT | phosphorylation up-regulates quantity by stabilization | 21049007 | SIGNOR-278928 |
| CSF1R | CTNND1 | Tyr904 | TKSLDNNySTPNERG | phosphorylation up-regulates quantity by stabilization | 21049007 | SIGNOR-278929 |
| CSF1R | CSF1R | Tyr561 | ESYEGNSyTFIDPTQ | phosphorylation down-regulates | 15297464 | SIGNOR-127622 |
| CSF1R | CSF1R | Tyr969 | PLLQPNNyQFC | phosphorylation down-regulates | 15297464 | SIGNOR-127626 |
| CSF1R | CSF1R | Tyr699 | DPEGGVDyKNIHLEK | phosphorylation up-regulates | 15297464 | SIGNOR-127536 |
| CSF1R | CSF1R | Tyr708 | NIHLEKKyVRRDSGF | phosphorylation up-regulates | 15297464 | SIGNOR-127540 |
| CSF1R | CSF1R | Tyr723 | SSQGVDTyVEMRPVS | phosphorylation up-regulates | 15297464 | SIGNOR-127614 |
| CSF1R | CSF1R | Tyr809 | DIMNDSNyIVKGNAR | phosphorylation up-regulates | 15297464 | SIGNOR-127618 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSF1R | phosphorylation up-regulates → | CTNND1 PTyr228 | phosphorylation up-regulates → | CTNND1 | 21049007 | SIGNOR-278928 |
| CSF1R | phosphorylation up-regulates → | CTNND1 PTyr904 | phosphorylation up-regulates → | CTNND1 | 21049007 | SIGNOR-278929 |
| CSF1R | phosphorylation up-regulates → | CSF1R PTyr561 | phosphorylation down-regulates ⊣ | CSF1R | 15297464 | SIGNOR-127622 |
| CSF1R | phosphorylation up-regulates → | CSF1R PTyr969 | phosphorylation down-regulates ⊣ | CSF1R | 15297464 | SIGNOR-127626 |
| CSF1R | phosphorylation up-regulates → | CSF1R PTyr699 | phosphorylation up-regulates → | CSF1R | 15297464 | SIGNOR-127536 |
| CSF1R | phosphorylation up-regulates → | CSF1R PTyr708 | phosphorylation up-regulates → | CSF1R | 15297464 | SIGNOR-127540 |
| CSF1R | phosphorylation up-regulates → | CSF1R PTyr723 | phosphorylation up-regulates → | CSF1R | 15297464 | SIGNOR-127614 |
| CSF1R | phosphorylation up-regulates → | CSF1R PTyr809 | phosphorylation up-regulates → | CSF1R | 15297464 | SIGNOR-127618 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CSF1R | phosphorylation → up-regulates quantity by stabilization | CTNND1 | SIGNOR-278928 |
| CSF1R | phosphorylation → up-regulates quantity by stabilization | CTNND1 | SIGNOR-278929 |
| CSF1R | phosphorylation down-regulates | CSF1R | SIGNOR-127622 |
| CSF1R | phosphorylation down-regulates | CSF1R | SIGNOR-127626 |
| CSF1R | phosphorylation → up-regulates | CSF1R | SIGNOR-127536 |
| CSF1R | phosphorylation → up-regulates | CSF1R | SIGNOR-127540 |
| CSF1R | phosphorylation → up-regulates | CSF1R | SIGNOR-127614 |
| CSF1R | phosphorylation → up-regulates | CSF1R | SIGNOR-127618 |