| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2A1 | HSP90AA1 | Ser263 | PEIEDVGsDEEEEKK | phosphorylation unknown | 2492519 | SIGNOR-250900 |
| CSNK2A1 | HSP90AA1 | Ser231 | KERDKEVsDDEAEEK | phosphorylation unknown | 2492519 | SIGNOR-250899 |
| PRKCG | HSP90AA1 | Thr603 | PCCIVTStYGWTANM | phosphorylation down-regulates | 24117238 | SIGNOR-202820 |
| PRKDC | HSP90AA1 | Thr5 | tQTQDQPM | phosphorylation unknown | 2507541 | SIGNOR-248887 |
| PRKCG | HSP90AA1 | Thr425 | KKCLELFtELAEDKE | phosphorylation down-regulates | 24117238 | SIGNOR-202816 |
| PRKDC | HSP90AA1 | Thr7 | tQDQPMEE | phosphorylation unknown | 2507541 | SIGNOR-248888 |
| PRKACA | HSP90AA1 | Thr90 | NKQDRTLtIVDTGIG | phosphorylation unknown | 21919888 | SIGNOR-176614 |
| PRKCG | HSP90AA1 | Thr115 | GTIAKSGtKAFMEAL | phosphorylation down-regulates | 24117238 | SIGNOR-202812 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2A1 | phosphorylation up-regulates → | HSP90AA1 PSer263 | phosphorylation down-regulates ⊣ | HSP90AA1 | 2492519 | SIGNOR-250900 |
| CSNK2A1 | phosphorylation up-regulates → | HSP90AA1 PSer231 | phosphorylation down-regulates ⊣ | HSP90AA1 | 2492519 | SIGNOR-250899 |
| PRKCG | phosphorylation up-regulates → | HSP90AA1 PThr603 | phosphorylation down-regulates ⊣ | HSP90AA1 | 24117238 | SIGNOR-202820 |
| PRKDC | phosphorylation up-regulates → | HSP90AA1 PThr5 | phosphorylation down-regulates ⊣ | HSP90AA1 | 2507541 | SIGNOR-248887 |
| PRKCG | phosphorylation up-regulates → | HSP90AA1 PThr425 | phosphorylation down-regulates ⊣ | HSP90AA1 | 24117238 | SIGNOR-202816 |
| PRKDC | phosphorylation up-regulates → | HSP90AA1 PThr7 | phosphorylation down-regulates ⊣ | HSP90AA1 | 2507541 | SIGNOR-248888 |
| PRKACA | phosphorylation up-regulates → | HSP90AA1 PThr90 | phosphorylation down-regulates ⊣ | HSP90AA1 | 21919888 | SIGNOR-176614 |
| PRKCG | phosphorylation up-regulates → | HSP90AA1 PThr115 | phosphorylation down-regulates ⊣ | HSP90AA1 | 24117238 | SIGNOR-202812 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CSNK2A1 | phosphorylation → unknown | HSP90AA1 | SIGNOR-250900 |
| CSNK2A1 | phosphorylation → unknown | HSP90AA1 | SIGNOR-250899 |
| PRKCG | phosphorylation down-regulates | HSP90AA1 | SIGNOR-202820 |
| PRKDC | phosphorylation → unknown | HSP90AA1 | SIGNOR-248887 |
| PRKCG | phosphorylation down-regulates | HSP90AA1 | SIGNOR-202816 |
| PRKDC | phosphorylation → unknown | HSP90AA1 | SIGNOR-248888 |
| PRKACA | phosphorylation → unknown | HSP90AA1 | SIGNOR-176614 |
| PRKCG | phosphorylation down-regulates | HSP90AA1 | SIGNOR-202812 |
