Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
YES1	SOCS1	Tyr80	LLDACGFyWGPLSVH	phosphorylation down-regulates activity	31101761	SIGNOR-276858
YES1	SOCS1	Tyr80	LLDACGFyWGPLSVH	phosphorylation up-regulates quantity by stabilization	31101761	SIGNOR-277453
YES1	ANXA2	Tyr24	HSTPPSAyGSVKAYT	phosphorylation up-regulates activity	33941853	SIGNOR-279435
YES1	YES1	Tyr426	RLIEDNEyTARQGAK	phosphorylation up-regulates activity	9794236	SIGNOR-247014
YES1	POU2F2	–		phosphorylation up-regulates activity	26979622	SIGNOR-279664
YES1	CDK4	Tyr17	AEIGVGAyGTVYKAR	phosphorylation down-regulates	18479465	SIGNOR-178624
YES1	YY1	–		phosphorylation down-regulates activity	26198631	SIGNOR-276941
YES1	YAP1	Tyr407	SGLSMSSySVPRTPD	phosphorylation up-regulates activity	23245941	SIGNOR-278248
YES1	YAP1	Tyr391	PFLNSGTyHSRDEST	phosphorylation up-regulates activity	35041461	SIGNOR-277652
YES1	YAP1	Tyr407	SGLSMSSySVPRTPD	phosphorylation up-regulates activity	35041461	SIGNOR-277653
YES1	GLO1	Tyr136	GIAVPDVySACKRFE	phosphorylation up-regulates activity	34838714	SIGNOR-276185
YES1	WBP2	Tyr192	MMDGAMGyVQPPPPP	phosphorylation up-regulates activity	21642474	SIGNOR-273581
YES1	WBP2	Tyr231	AEAAASAyYNPGNPH	phosphorylation up-regulates activity	21642474	SIGNOR-273582
YES1	WWTR1	Tyr305	PFLNGGPyHSREQST	phosphorylation up-regulates activity	35041461	SIGNOR-277654

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
YES1	phosphorylation up-regulates →	SOCS1 PTyr80	phosphorylation down-regulates ⊣	SOCS1	31101761	SIGNOR-276858
YES1	phosphorylation up-regulates →	SOCS1 PTyr80	phosphorylation up-regulates →	SOCS1	31101761	SIGNOR-277453
YES1	phosphorylation up-regulates →	ANXA2 PTyr24	phosphorylation up-regulates →	ANXA2	33941853	SIGNOR-279435
YES1	phosphorylation up-regulates →	YES1 PTyr426	phosphorylation up-regulates →	YES1	9794236	SIGNOR-247014
YES1	phosphorylation up-regulates →	CDK4 PTyr17	phosphorylation down-regulates ⊣	CDK4	18479465	SIGNOR-178624
YES1	phosphorylation up-regulates →	YAP1 PTyr407	phosphorylation up-regulates →	YAP1	23245941	SIGNOR-278248
YES1	phosphorylation up-regulates →	YAP1 PTyr391	phosphorylation up-regulates →	YAP1	35041461	SIGNOR-277652
YES1	phosphorylation up-regulates →	YAP1 PTyr407	phosphorylation up-regulates →	YAP1	35041461	SIGNOR-277653
YES1	phosphorylation up-regulates →	GLO1 PTyr136	phosphorylation up-regulates →	GLO1	34838714	SIGNOR-276185
YES1	phosphorylation up-regulates →	WBP2 PTyr192	phosphorylation up-regulates →	WBP2	21642474	SIGNOR-273581
YES1	phosphorylation up-regulates →	WBP2 PTyr231	phosphorylation up-regulates →	WBP2	21642474	SIGNOR-273582
YES1	phosphorylation up-regulates →	WWTR1 PTyr305	phosphorylation up-regulates →	WWTR1	35041461	SIGNOR-277654

Regulator	Mechanism/Effect	Target	SIGNOR-ID
YES1	phosphorylation → down-regulates activity	SOCS1	SIGNOR-276858
YES1	phosphorylation → up-regulates quantity by stabilization	SOCS1	SIGNOR-277453
YES1	phosphorylation → up-regulates activity	ANXA2	SIGNOR-279435
YES1	phosphorylation → up-regulates activity	YES1	SIGNOR-247014
YES1	phosphorylation → up-regulates activity	POU2F2	SIGNOR-279664
YES1	phosphorylation down-regulates	CDK4	SIGNOR-178624
YES1	phosphorylation → down-regulates activity	YY1	SIGNOR-276941
YES1	phosphorylation → up-regulates activity	YAP1	SIGNOR-278248
YES1	phosphorylation → up-regulates activity	YAP1	SIGNOR-277652
YES1	phosphorylation → up-regulates activity	YAP1	SIGNOR-277653
YES1	phosphorylation → up-regulates activity	GLO1	SIGNOR-276185
YES1	phosphorylation → up-regulates activity	WBP2	SIGNOR-273581
YES1	phosphorylation → up-regulates activity	WBP2	SIGNOR-273582
YES1	phosphorylation → up-regulates activity	WWTR1	SIGNOR-277654