Entity Details

Name YES1
ID P07947
Role substrate
Enzymatic Domains
SH3 91-152
PROSITE-ProRule
SH2 158-255
PROSITE-ProRule
Protein kinase 277-530
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AXLYES1Tyr426RLIEDNEyTARQGAKphosphorylation
up-regulates activity		33941853SIGNOR-277555
YES1YES1Tyr426RLIEDNEyTARQGAKphosphorylation
up-regulates activity		9794236SIGNOR-247014
IL6STYES1–phosphorylation
up-regulates activity		31296870SIGNOR-278033
EPHA2YES1Tyr426RLIEDNEyTARQGAKphosphorylation
up-regulates activity		33941853SIGNOR-277556
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AXLphosphorylation
up-regulates
→
YES1
PTyr426		phosphorylation
up-regulates
→		YES133941853SIGNOR-277555
YES1phosphorylation
up-regulates
→
YES1
PTyr426		phosphorylation
up-regulates
→		YES19794236SIGNOR-247014
EPHA2phosphorylation
up-regulates
→
YES1
PTyr426		phosphorylation
up-regulates
→		YES133941853SIGNOR-277556
Regulator Mechanism/Effect Target SIGNOR-ID
AXLphosphorylation
→
up-regulates activity 		YES1SIGNOR-277555
YES1phosphorylation
→
up-regulates activity 		YES1SIGNOR-247014
IL6STphosphorylation
→
up-regulates activity 		YES1SIGNOR-278033
EPHA2phosphorylation
→
up-regulates activity 		YES1SIGNOR-277556