Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
CSK	LYN	Tyr508 View in OncoXplorer	YTATEGQyQQQP	phosphorylation down-regulates	15626731	SIGNOR-132912
MATK	LYN	Tyr508 View in OncoXplorer	YTATEGQyQQQP	phosphorylation down-regulates activity	9171348	SIGNOR-250177
PTPRO	LYN	–		dephosphorylation down-regulates activity	20564182	SIGNOR-277144
EGFR	LYN	Tyr32	RNTERTIyVRDPTSN	phosphorylation up-regulates activity	23764002	SIGNOR-279369
PTPN6	LYN	Tyr397 View in OncoXplorer	RVIEDNEyTAREGAK	dephosphorylation down-regulates activity	15537644	SIGNOR-248471
CSNK1G1	LYN	Ser13 View in OncoXplorer	SKGKDSLsDDGVDLK	phosphorylation up-regulates quantity by stabilization	33004926	SIGNOR-275396
PTPRC	LYN	Tyr508 View in OncoXplorer	YTATEGQyQQQP	dephosphorylation down-regulates activity	10415030	SIGNOR-248354
CSNK1G3	LYN	Ser13 View in OncoXplorer	SKGKDSLsDDGVDLK	phosphorylation up-regulates quantity by stabilization	33004926	SIGNOR-275395
PTPRA	LYN	Tyr397 View in OncoXplorer	RVIEDNEyTAREGAK	dephosphorylation down-regulates activity	15537644	SIGNOR-248436
PTPRC	LYN	Tyr397 View in OncoXplorer	RVIEDNEyTAREGAK	dephosphorylation down-regulates activity	10415030	SIGNOR-248353
LYN	LYN	Tyr397 View in OncoXplorer	RVIEDNEyTAREGAK	phosphorylation up-regulates activity	8530369	SIGNOR-251402
CSNK1G2	LYN	Ser13 View in OncoXplorer	SKGKDSLsDDGVDLK	phosphorylation up-regulates quantity by stabilization	33004926	SIGNOR-275397

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
CSK	phosphorylation up-regulates →	LYN PTyr508	phosphorylation down-regulates ⊣	LYN	15626731	SIGNOR-132912
MATK	phosphorylation up-regulates →	LYN PTyr508	phosphorylation down-regulates ⊣	LYN	9171348	SIGNOR-250177
EGFR	phosphorylation up-regulates →	LYN PTyr32	phosphorylation up-regulates →	LYN	23764002	SIGNOR-279369
PTPN6	dephosphorylation down-regulates ⊣	LYN PTyr397	dephosphorylation up-regulates →	LYN	15537644	SIGNOR-248471
CSNK1G1	phosphorylation up-regulates →	LYN PSer13	phosphorylation up-regulates →	LYN	33004926	SIGNOR-275396
PTPRC	dephosphorylation down-regulates ⊣	LYN PTyr508	dephosphorylation up-regulates →	LYN	10415030	SIGNOR-248354
CSNK1G3	phosphorylation up-regulates →	LYN PSer13	phosphorylation up-regulates →	LYN	33004926	SIGNOR-275395
PTPRA	dephosphorylation down-regulates ⊣	LYN PTyr397	dephosphorylation up-regulates →	LYN	15537644	SIGNOR-248436
PTPRC	dephosphorylation down-regulates ⊣	LYN PTyr397	dephosphorylation up-regulates →	LYN	10415030	SIGNOR-248353
LYN	phosphorylation up-regulates →	LYN PTyr397	phosphorylation up-regulates →	LYN	8530369	SIGNOR-251402
CSNK1G2	phosphorylation up-regulates →	LYN PSer13	phosphorylation up-regulates →	LYN	33004926	SIGNOR-275397

Regulator	Mechanism/Effect	Target	SIGNOR-ID
CSK	phosphorylation down-regulates	LYN	SIGNOR-132912
MATK	phosphorylation → down-regulates activity	LYN	SIGNOR-250177
PTPRO	dephosphorylation → down-regulates activity	LYN	SIGNOR-277144
EGFR	phosphorylation → up-regulates activity	LYN	SIGNOR-279369
PTPN6	dephosphorylation → down-regulates activity	LYN	SIGNOR-248471
CSNK1G1	phosphorylation → up-regulates quantity by stabilization	LYN	SIGNOR-275396
PTPRC	dephosphorylation → down-regulates activity	LYN	SIGNOR-248354
CSNK1G3	phosphorylation → up-regulates quantity by stabilization	LYN	SIGNOR-275395
PTPRA	dephosphorylation → down-regulates activity	LYN	SIGNOR-248436
PTPRC	dephosphorylation → down-regulates activity	LYN	SIGNOR-248353
LYN	phosphorylation → up-regulates activity	LYN	SIGNOR-251402
CSNK1G2	phosphorylation → up-regulates quantity by stabilization	LYN	SIGNOR-275397