Entity Details

Name CSK_Tyr508
ID P07948
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MATKLYNTyr508YTATEGQyQQQPphosphorylation
down-regulates activity		9171348SIGNOR-250177
CSKLYNTyr508YTATEGQyQQQPphosphorylation
down-regulates		15626731SIGNOR-132912
PTPRCLYNTyr508YTATEGQyQQQPdephosphorylation
down-regulates activity		10415030SIGNOR-248354
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MATKphosphorylation
up-regulates
→
LYN
PTyr508		phosphorylation
down-regulates
⊣		LYN9171348SIGNOR-250177
CSKphosphorylation
up-regulates
→
LYN
PTyr508		phosphorylation
down-regulates
⊣		LYN15626731SIGNOR-132912
PTPRCdephosphorylation
down-regulates
⊣
LYN
PTyr508		dephosphorylation
up-regulates
→		LYN10415030SIGNOR-248354
Regulator Mechanism/Effect Target SIGNOR-ID
MATKphosphorylation
→
down-regulates activity 		LYNSIGNOR-250177
CSKphosphorylation
img/direct_inhibition.png
down-regulates 		LYNSIGNOR-132912
PTPRCdephosphorylation
→
down-regulates activity 		LYNSIGNOR-248354