Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
MATK	LYN	Tyr508 View in OncoXplorer	YTATEGQyQQQP	phosphorylation down-regulates activity	9171348	SIGNOR-250177
CSK	LYN	Tyr508 View in OncoXplorer	YTATEGQyQQQP	phosphorylation down-regulates	15626731	SIGNOR-132912
PTPRC	LYN	Tyr508 View in OncoXplorer	YTATEGQyQQQP	dephosphorylation down-regulates activity	10415030	SIGNOR-248354

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
MATK	phosphorylation up-regulates →	LYN PTyr508	phosphorylation down-regulates ⊣	LYN	9171348	SIGNOR-250177
CSK	phosphorylation up-regulates →	LYN PTyr508	phosphorylation down-regulates ⊣	LYN	15626731	SIGNOR-132912
PTPRC	dephosphorylation down-regulates ⊣	LYN PTyr508	dephosphorylation up-regulates →	LYN	10415030	SIGNOR-248354

Regulator	Mechanism/Effect	Target	SIGNOR-ID
MATK	phosphorylation → down-regulates activity	LYN	SIGNOR-250177
CSK	phosphorylation down-regulates	LYN	SIGNOR-132912
PTPRC	dephosphorylation → down-regulates activity	LYN	SIGNOR-248354