Entity Details

Name GJB1
ID P08034
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKCAGJB1Ser229QRRSNPPsRKGSGFGphosphorylation
up-regulates activity		8390988SIGNOR-248919
PRKCAGJB1Ser233
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NPPSRKGsGFGHRLSphosphorylation
up-regulates activity		8390988SIGNOR-248920
PRKACAGJB1Ser233
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NPPSRKGsGFGHRLSphosphorylation
unknown		8390988SIGNOR-249715
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PRKCAphosphorylation
up-regulates
→
GJB1
PSer229		phosphorylation
up-regulates
→		GJB18390988SIGNOR-248919
PRKCAphosphorylation
up-regulates
→
GJB1
PSer233		phosphorylation
up-regulates
→		GJB18390988SIGNOR-248920
PRKACAphosphorylation
up-regulates
→
GJB1
PSer233		phosphorylation
down-regulates
⊣		GJB18390988SIGNOR-249715
Regulator Mechanism/Effect Target SIGNOR-ID
PRKCAphosphorylation
→
up-regulates activity 		GJB1SIGNOR-248919
PRKCAphosphorylation
→
up-regulates activity 		GJB1SIGNOR-248920
PRKACAphosphorylation
→
unknown 		GJB1SIGNOR-249715