Entity Details

Name GRK2_Ser1278
ID P08069
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
GRK2IGF1RSer1278EPGFREVsFYYSEENphosphorylation
down-regulates quantity by destabilization		22509025SIGNOR-276413
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
GRK2phosphorylation
up-regulates
→
IGF1R
PSer1278		phosphorylation
down-regulates
⊣		IGF1R22509025SIGNOR-276413
Regulator Mechanism/Effect Target SIGNOR-ID
GRK2phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		IGF1RSIGNOR-276413