Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
SRC	IGF1R	Tyr1165 View in OncoXplorer	RDIYETDyYRKGGKG	phosphorylation up-regulates	7493944	SIGNOR-246264
SRC	IGF1R	Tyr1165 View in OncoXplorer	RDIYETDyYRKGGKG	phosphorylation up-regulates	8940173	SIGNOR-45126
IGF1R	IGF1R	Tyr1165 View in OncoXplorer	RDIYETDyYRKGGKG	phosphorylation up-regulates	7493944	SIGNOR-26586

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
SRC	phosphorylation up-regulates →	IGF1R PTyr1165	phosphorylation up-regulates →	IGF1R	7493944	SIGNOR-246264
SRC	phosphorylation up-regulates →	IGF1R PTyr1165	phosphorylation up-regulates →	IGF1R	8940173	SIGNOR-45126
IGF1R	phosphorylation up-regulates →	IGF1R PTyr1165	phosphorylation up-regulates →	IGF1R	7493944	SIGNOR-26586

Regulator	Mechanism/Effect	Target	SIGNOR-ID
SRC	phosphorylation → up-regulates	IGF1R	SIGNOR-246264
SRC	phosphorylation → up-regulates	IGF1R	SIGNOR-45126
IGF1R	phosphorylation → up-regulates	IGF1R	SIGNOR-26586